Setiagung Ambari Bowo
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Bacterial Pathogens And Antibiotic Sensitivity Pattern In Burn Unit Of Hasan Sadikin Hospital (RSHS) From January 2012 - December 2015 Setiagung Ambari Bowo; Almahita Cintami Putri
Jurnal Plastik Rekonstruksi Vol. 3 No. 2 (2016): July Issue
Publisher : Lingkar Studi Bedah Plastik Foundation

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (617.264 KB) | DOI: 10.14228/jpr.v3i2.199

Abstract

Background : Infection is the common cause of death following burn injury. Antibiotic resistance is a major wide problem in burn unit. We evaluated the pattern of bacterial pathogens isolated from burn wound and sensitivity of antibiotics in burn unit of RSHS. Method : A retrospective descriptive study has been done in Burn Unit RSHS by collecting data from burn unit patient’s medical records over 4 years (2012-2015). Data of demography, characteristic of patients, wound isolates bacteria and sensitivity was collected. Result : A total of 205 patients were admitted to burn unit of RSHS and 164 patients fulfilled the requirements to be analyzed. 114 (69.5%) patients were male and the most commonly affected age groups were young adults 15-40 years old. The mortality rate in burn unit was 71 patients (43.3%) and Acute Respiratory Distress Syndrome (ARDS) was commonly the primary cause of death (53.5%) and followed by sepsis (42.3%). Microorganism from burn wound isolates were P. aeruginosa (30.1%), A. baumanii (19.9%), K. pneumonia (19.3%), E. cloacae (9.1%), E. coli (4%), P. stuartii (2.8%). Meropenem was the most sensitive antibiotic against to P. aeruginosa and K. pneumonia. Amikasin was shown to be sensitive to A. baumanii, E. cloacae and E. coli. P. stuartii was 100% sensitive to meropenem, amikasin, piperacillin-tazobactam and cotrimoxazole. Cefoperazon, ceftriaxone and ceftazidime showed very low sensitivity (0-14.3%). Conclusion : Dominant bacteria isolated was P. aeruginosa which was sensitive to meropenem and commonly resistant to the third generation of cephalosporin antibiotics, which becomes multi drug resistant bacteria.
Effectiveness Of Early Excisional Debridement In Burn Injuries To Sepsis Incidence And Mortality Rate At Burn Unit Of Hasan Sadikin Hospital Setiagung Ambari Bowo; Hardisiswo Soedjana
Jurnal Plastik Rekonstruksi Vol. 3 No. 2 (2016): July Issue
Publisher : Lingkar Studi Bedah Plastik Foundation

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (536.271 KB) | DOI: 10.14228/jpr.v3i2.200

Abstract

Background: Sepsis is an important cause of mortality in patients with burn, although many factors influence it. Early excision debridement as source control treatment has been done routinely in our center. It was intended to prevent sepsis and decrease mortality rate. Methods: We performed a retrospective, cross sectional study over 4 years (2012-2014) among patients with flame burns in Burn Unit Dr. Hasan Sadikin Hospital who underwent early excisional debridement. The criteria of patients were adult, with full thickness burn, without inhalation injury and co morbid disease. The mortality, length of stay, and incidence of sepsis were analyzed by simple regression linier statistics using SPSS 16.0 for Windows. Results: Mortality rate of all patients was 43.3%, and 42.3% was directly caused by sepsis. Thirty-nine patients matched the criteria, 20 patients had early excision (< 3 days) and 19 patients had late excision (> 3 days). In early excision group, 75% got sepsis and 55% died. Mortality and incidence of sepsis wasn’t significantly different in both groups (p=0.252 and p=0.855). Both groups have same length of stay (mean : 13.1 and p=0.236). Sex as confounding factor wasn’t significantly different (p=0.774). The extent of TBSA and age were significant factors causing mortality rate (p < 0.05). Conclusion: There are many factors that contribute to the success of treating burn patient. Excision debridement was proven by this study not a major factor and ineffective to decrease sepsis and mortality in burned patients.