Article Per Year (5 Year)
p-Index From 2019 - 2024
0.659
P-Index
This Author published in this journals
All Journal JCPS (Journal of Current Pharmaceutical Sciences) Journal of Innovation Research and Knowledge
Rizka Mulya Miranti
Universitas Muhammadiyah Banjarmasin
Humanities Economics, Econometrics & Finance Education Health Professions Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Social Sciences

Published : 3 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 3 Documents
Search

 1 
PENGARUH PEMBERIAN DAGING SIPUT SAWAH (Filopaludina javanica v.d Busch 1844)TERHADAP PENYEMBUHAN TUKAK LAMBUNG PADA TIKUS WISTAR BETINA YANG DIINDUKSI ASETOSAL Rizka Mulya Miranti; Andreanus A. Soemardji; Siti Kusmardiyani
JCPS (Journal of Current Pharmaceutical Sciences) Vol 4 No 1 (2020): September 2020
Publisher : LPPM - Universitas Muhammadiyah Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

ABSTRAK Siput sawah (Filopaludina javanica v.d Busch 1844) telah digunakan oleh masyarakat Jawa Barat untuk mengobati tukak lambung secara empiris, namun belum ada penelitian yang membuktikan efek tersebut. Pengujian ini merupakan pengujian farmakologi yang bertujuan mengetahui penurunan indeks tukak lambung pada tikus yang diinduksi asetosal. Induksi asetosal dosis 405 mg/kg diberikan selama 10 hari. Daging siput sawah yang telah direbus diberikan selama tiga hari dengan dosis 3,310 g/kg dan dosis 6,620 g/kg. Obat pembanding yang digunakan adalah Lansoprazol dosis 5 mg/kg. Hasil pengujian menunjukan bahwa persentasi penyembuhan dosis 3,310 g/kg adalah sebesar 4,92 % dan dosis 6,620 g/kg sebesar 8,20 %. Indeks tukak lambung pada tikus kelompok uji lebih rendah dari kelompok kontrol positif dengan signifikasi P>0,05. Kata kunci : Siput sawah, Filopaludina javanica v.d Busch 1844, antitukak lambung, asetosal ABSTRACT People in West Java consume rice field snail (Filopaludina javanica v.d Busch 1844) to treat peptic ulcers but no scientific studies have proven that effect. This research is a pharmacological test that aims to determine the reduction in the index of peptic ulcers in mice indusced by acetosal. Rat-peptic ulcer model was induced with acetosal 405 mg/kg body weight for 10 days. Boiled rice snail meat is given for three days at a dose of 3,310 g / kg and a dose of 6,620 g / kg. The comparison drug used is Lansoprazol dose of 5 mg / kg. The results showed that the gastric ulcer healing dose 3,310 g/kg and 6,620 g/kg were 4,92% and 8,20%. Peptic ulcer index in the test group mice was lower than the positive control group even though there was no significant difference (P> 0.05). Keyword: Rice field snail, Filopaludina javanica v.d. Busch 1844, Peptic ulcer activity, Acetosal
FORMULASI DAN UJI SIFAT FISIK ESSENCE DARI EKSTRAK KULIT BUAH BALANGKASUA (Lepisanthes alata (Blume) Leenh) Eliza Ardika; Aris Purwanto; Rizka Mulya Miranti
JCPS (Journal of Current Pharmaceutical Sciences) Vol 5 No 2 (2022): March 2022
Publisher : LPPM - Universitas Muhammadiyah Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Buah balangkasua ini memiliki kandungan antioksidan yang cukup tinggi. Penelitian ini bertujuan untuk memformulasikan sediaan essence yang mengandung ekstrak kulit buah balangkasua serta melakukan uji sifat fisik sedian. Metode penelitian yang digunakan adalah metode eksperimental yaitu ekstrak diperoleh dengan menggunakan metode maserasi, kemudian diformulasi menjadi sediaan essence dengan variasi penambahan ekstrak kulit buah balangkasua masing-masing (FI) kontrol, FII (1%), FIII (3%), FIV (5%). Dilakukan uji sifat fisik sediaan yaitu uji organoleptis, uji pH, uji Homogenitas, uji viskositas dan uji hedonik. Data yang diperoleh dianalisis secara statistik ANOVA (Analysis of Variance) dengan nilai signifikansi 0,05. Hasil penelitian menunjukkan bahwa sediaan essence memiliki warna merah-coklat muda hingga merah- coklat tua dengan pH 4,5-7, sediaan homogen, viskositas 8,434-13,040 Poise dan uji hedonik warna 70%- 83%, aroma 70%-77%, bentuk 82%-87% dan kesan lembab 78-88%. Variasi konsentrasi ekstrak berpengaruh signifikan terhadap pH dan viskositas essence dari ekstrak kulit buah balangkasua dengan nilai signifikasi <0,05.
EFEKTIVITAS INFUSA JAHE MERAH (ZINGIBER OFFICINALE VAR. RUBRUM) SEBAGAI ANTIDIARE PADA MENCIT PUTIH JANTAN YANG DI INDUKSI OLEUM RICINI DENGAN METODE TRANSIT INTESTINAL Yulis Azizah; Rizka Mulya Miranti; Dedi Hartanto; Retna Eka Dewi
Journal of Innovation Research and Knowledge Vol. 3 No. 3: Agustus 2023
Publisher : Bajang Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53625/jirk.v3i3.6348

Abstract

Red ginger is a plant of the Zingiberaceae family which contains active compounds which are consider to have a major contribution to the anti-diarrheal effect are steroids, tannins, flavonoids, and saponins. The purpose of this study was to determine if red ginger infusion has an antidiarrheal effect and what is the effective dose if it has an anti- diarrheal effect. This research is an experimental with a Completely Randomised plan (CRP) with a one way model. Twenty-four mice were randomly assigned to 6 groups of 4 mice within each group. The Red ginger infusion was tested with 3 different dosage variations; 1.047 g/kgBW, 2.095 g/kgBW, and 4.19 g/kgBW. The Antidiarrheal activity in this study was determined by computing the ratio of the bowel length passed through the marker to total length of the intestine. The results showed that red ginger infusion has an anti-diarrheal effect. Infusion of red ginger at doses of 1.047 g/kg BB, 2.095 g/kg BB and 4.19 g/kgBW, resulting in average ratios of 0.596, 0.37975 and 0.164125, consecutively. Based on a statiscal data analysis with the Mann Whitney Test, it was obtained that the ratio between a dose of 4.19 g / kgBW and the Loperamide comparison group of 4 mg / kgBW dose did not have a meaningful difference. So the most effective dose of red ginger infusion as an anti-diarrhea is 4.19 g/kgBW.
Co-Authors Andreanus A. Soemardji Aris Purwanto Dedi Hartanto Eliza Ardika Retna Eka Dewi Siti Kusmardiyani Yulis Azizah