M. Syamsuddin Wisnubroto
Institut Teknologi Sumatera

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The Implementation of Regularized Markov Clustering with Pigeon Inspired Optimization Algorithm in Analyzing the SARS-CoV-2 (COVID-19) Protein Interaction Network M. Syamsuddin Wisnubroto; Marsudi Siburian; Febri Dwi Irawati
Desimal: Jurnal Matematika Vol 3, No 3 (2020): Desimal: Jurnal Matematika
Publisher : Universitas Islam Negeri Raden Intan Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (964.397 KB) | DOI: 10.24042/djm.v3i3.6822

Abstract

Proteins interact with other proteins, DNA, and other molecules, forming large-scale protein interaction networks and for easy analysis, clustering methods are needed. Regularized Markov clustering algorithm is an improvement of MCL where operations on expansion are replaced by new operations that update the flow distributions of each node. But to reduce the weaknesses of the RMCL optimization, Pigeon Inspired Optimization Algorithm (PIO) is used to replace the inflation parameters. The simulation results of IPC SARS-Cov-2 (COVID-19) inflation parameters  get the result of 42 proteins as the center of the cluster and 8 protein pairs interacting with each other. Proteins of COVID-19 that interact with 20 or more proteins are ORF8, NSP13, NSP7, M, N, ORF9C, NSP8, and NSP1. Their interactions might be used as a target for drug research.
Redesigning UI/UX of A Mobile Application Using Task Centered System Design Approach Mugi Praseptiawan; Meida Cahyo Untoro; Feri Fahrianto; Pungki Resti Prabandari; M. Syamsuddin Wisnubroto
Applied Information System and Management (AISM) Vol 6, No 1 (2023): Applied Information System and Management (AISM)
Publisher : Depart. of Information Systems, FST, UIN Syarif Hidayatullah Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15408/aism.v6i1.24665

Abstract

Digital transformation requires a software system development method to identify and analyze user needs. In this research, software system development uses the Task Centered System Design framework with several stages, including identification, needs analysis, design, and evaluation. The identification stage is carried out by conducting interviews with stakeholders, and then the results of the interviews are analyzed and approved by stakeholders. This study aims to obtain user needs to build an application interface by applying the steps of the Task Centered System Design method and usability evaluation and calculating the weight of the feasibility value by testing the Heuristics method and System Usability Scale on the solution application design. The evaluation phase aims to determine the value of the usability problem in the design that has been designed. The evaluation phase uses the Usability Heuristic method by involving experts in the field of software development and the System Usability Scale method involving end users. After conducting research from the identification to the evaluation stage, the average severity rating of the Heuristic Usability test component scored less than 1 (one) in the second iteration, and the System Usability Scale results scored 70.3 for admin and 73.75 for the customer application. This result is in grade C with an adjective rating of Good.