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IDENTIFIKASI KADAR GLUKOSA DAN SUKROSA PADA MADU HUTAN ZUHAIRIAH NST; ERNALA BR GINTING; DYNA GRACE ROMATUA; FIRDAUS FAHDI
Jurnal Penelitian Farmasi & Herbal Vol 1 No 2 (2019): Jurnal Penelitian Farmasi & Herbal
Publisher : Fakultas Farmasi Institut Kesehatan DELI HUSADA Deli Tua

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jpfh.v1i2.62

Abstract

Abstract Glucose and sucrose tests are performed as one of honey’s standard quality. Meanwhile the process of honey production by bees itself is a complex process, so there is a high probability of differences in the levels and composition of glucose and sucrose among the types of honey circulating in the community. The composition of glucose and sucrose of each honey can affect its efficacy mainly when it is used for treatment process. The aim of this research is to know glucose and sucrose level in forest honey and compare it with honey’s standard quality according to Indonesian national standard (SNI 01-3545-2013). The samples were 3 forest honey from different village. Sample A is forest honey from Kubu Simbelang Village, Sample B from Bunuraya Village, and Sample C from Suka Village, Tigapanah District. The determination of glucose and sucrose levels was performed by Luff Schoorl method. The result of this study was glucose average level of each sample A, B and C is 71,42%, 66,24%, and 71,21%. The sucrose average levels of sample A, B, and C is 3,09%, 4,51, and 3,04%.It can be stated thatall forest honey used in this study has fulfilled the requirements according to SNI 01-3545-2013 which set that glucose level of honey must be at least 65%while the sucrose level is maximum 5%.
GAMBARAN KEJADIAN EKSTRAPIRAMIDAL SINDROM PADA PASIEN TERAPI ANTIPSIKOTIK TIPIKAL DI RUMAH SAKIT JIWA ACEH Vivi Asfianti; Alfi Syahfitri; Zuhairiah NST
FORTE JOURNAL Vol 2 No 2 (2022): Edisi Juli 2022
Publisher : Universitas Haji Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51771/fj.v2i2.367

Abstract

The use of antipsychotics in schizophrenic patients often causes side effects in the form of Extra Pyramidal Syndrome (EPS), namely the presence of uncontrolled muscle movement disorders such as seizures, shaking and so on. The incidence of EPS is more common with the use of typical antipsychotics than atypicals. This study aims to see the incidence of EPS in inpatients with schizophrenia at the Aceh Mental Hospital located in Banda Aceh in 2020. The population in this study were all inpatients who were given typical antipsychotics. While the research sample was 399 samples collected from medical record data of inpatients in 2020, so the study was retrospective with a cross sectional approach. Data collected in the form of patient identity (gender, age), drug therapy (typical antipsychotics) and the incidence of EPS. The results showed that schizophrenic patients who received typical antipsychotic therapy who were hospitalized at the Aceh mental hospital in 2020, were 324 men (81.2%) and 75 women (18.8%), with the highest age range being at 36-45 years amounting to 202 people (50.6%). Typical antipsychotic therapy used in the form of combination of typical-typical and typical-atypical drugs, namely clozapine-trifluperazine (40.6%), chlorpromazine-risperidone (20.3%), haloperidol-chlorpromazine-trifluperazine (16%), haloperidolchlorpromazine (7%), and haloperidol-trifluperazine (5%). The incidence of EPS that occurred was 113 people (28.3%), with the highest number of EPS occurring from the administration of haloperidol-chlorpromazine-trifluperazine combination antipsychotic therapy, which was 61 people (15.3%).
Penerapan Serta Validasi Metode Spektrofotometri Inframerah Pada Penetapan Kadar Ibuprofen Dalam Sediaan Tablet Zuhairiah Nst; Nerdy Nerdy; Rifoni Simbolon
Herbal Medicine Journal Vol 3 No 2 (2020): Herbal Medicine Journal
Publisher : Program Studi S1 Farmasi, STIKES Senior, Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (670.007 KB)

Abstract

Ibuprofen is one of drugs, which was used in medication rematic and arthritis, The purpose of this research was used to determination ibuprofen in the tablet, which circulates in the general whether it fulfilled requirement of drug quality, or not so that it will give the therapeutic effect. The determining of ibuprofen in tablet was done by Infrared Spectrophotometry using Methanol as a solvent at wavenumber 1709,0 cm-1 and tested it validity based on parameter accuracy using standard addition method, precision, limit of detection and limit of quantitation. Based on quantitative determination of ibuprofen in generic tablet ; Ibuprofen Sampel A was 98,36% ± 0,15%. Ibuprofen Sampel B was 102,38%± 0,21% and branded name, Sampel C, D, E in succession was 97,10% ± 0,18%; 99,34% ± 0,24%; was 103,33% ± 0,19%. The result of research indicate that determining ibuprofen in the generic tablet and branded name was fullfilled requirement of the Farmakope Indonesia Edisi IV (1995), not less than 90,0% and not more than 110,0% of the labelled amount.