Aji Winanta
Program Studi Farmasi, Fakultas Kedokteran dan Ilmu Kesehatan, Universitas Muhammadiyah Yogyakarta

Published : 2 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 2 Documents
Search

Peningkatan Pengetahuan Penggunaan Obat untuk Siswa Sekolah Dasar Aji Winanta; Mega Octavia; M. Fariez Kurniawan
Berdikari: Jurnal Inovasi dan Penerapan Ipteks Vol 8, No 2 (2020): August
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/bdr.8280

Abstract

Public understanding of the use of drugs that are not true can cause new health problems. This empowerment activity aims to increase people’s understanding on medicine. This activity was conducted at SD Muhammadiyah Demangan Yogyakarta. The activities were conducted in stages, including joint program planning, tutorials (lectures), practice of recognizing and understanding medicine, mentoring, and recitation on understanding medicine. The main topic of discussion is knowledge about medicine, then added knowledge about healthy snacks, vitamins and their benefits for the body, as well as the role of the pharmacist profession in pharmaceutical services. The results of this service show an increase in the understanding of elementary school students about the use of drugs, healthy snacks, vitamins and their functions for the body as well as knowledge related to the pharmacist profession. There were 26 students of the 30 students who participated in the drug use assistance whose posttest scores improved compared to the pretest scores.
Aktivitas antikanker ekstrak etanol, fraksi n-heksan, dan etil asetat daun tin (Ficus carica l.) pada sel kanker payudara MCF-7 Aji Winanta; Widhi Yana Sari
Jurnal Ilmiah Farmasi Vol. 19 No. 1 (2023): Jurnal Ilmiah Farmasi
Publisher : Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/jif.vol19.iss1.art4

Abstract

Abstract Background: Breast cancer is ranked as the second-highest cause of death in Indonesia. Many of the available cancer treatments result in severe adverse effects for patients. Tin (Ficus carica L.) leaves contain ingredients that can function as anticancer agents. Objective: The study aims to identify phytochemical secondary metabolites in tin leaves and the cytotoxic activity of the extract and tin leaf fraction on MCF-7 cells.Method: Tin leaf powder was macerated with 70% ethanol for 7 days. The extracts were fractionated using n-hexane and ethyl acetate. An identification test with ethanol extract was then carried out using spray reagents. The cytotoxic activity of ethanolic extract, n-hexane and ethyl acetate fraction of tin leaf was determined using the MTT method.Result: The results of the identification with TLC found that the ethanol extract of tin leaves contains flavonoids and steroids. The ethyl acetate fraction of tin leaf was thought to have weak cytotoxic properties with an IC50 value of 274.5877 ug/mL while the ethanol extract and n-heksan fraction of tin leaf do not have cytotoxic properties because they have an IC50 value of 562.827 and 576.3552 ug/mL. Conclusion: Based on the results, tin leaves have the potency to be developed as a chemopreventive agent for MCF-7 breast cancer cells.Keywords: Breast Cancer, MCF-7 cells, tin leaf (Ficus carica), cytotoxic activity