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All Journal Jurnal Teknik Industri Jurnal Energi Dan Manufaktur Medical Journal of Indonesia Metalurgi Makara Journal of Technology Metalurgi
Bambang Suharno
Departemen Metalurgi Dan Material, Fakultas Teknik, Universitas Indonesia, Depok 16424, Indonesia
Chemical Engineering, Chemistry & Bioengineering Civil Engineering, Building, Construction & Architecture Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Electrical & Electronics Engineering Energy Engineering Industrial & Manufacturing Engineering Materials Science & Nanotechnology Mechanical Engineering Medicine & Pharmacology

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Journal : Medical Journal of Indonesia

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The potential of carbonate apatite as an alternative bone substitute material Rahyussalim, Ahmad Jabir; Supriadi, Sugeng; Marsetio, Aldo Fransiskus; Pribadi, Pancar Muhammad; Suharno, Bambang
Medical Journal of Indonesia Vol 28, No 1 (2019): March
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (339.221 KB) | DOI: 10.13181/mji.v28i1.2681

Abstract

Bone reconstructive surgery has become a common procedure, and bone transplantation has become the second most frequently performed tissue transplantation procedure worldwide. Therefore, the need for bone substitute materials has increased. Artificial bone substitutes exhibit osteoconductive properties and feature several advantages, including abundant resources, low cost, and low donor site morbidity. Carbonate apatite (CO3Ap) is a calcium phosphate ceramic that can be used as a synthetic bone graft. The carbonate content of this ceramic is similar to that of bone apatite. In this review, we show that carbonate apatite can be degraded given its chemical reactivity in a weakly acidic environment and through osteoclast resorption. Moreover, it is osteoconductive and promotes bone tissue formation without fibrotic tissue formation. Additionally, microstructural analysis revealed that new bone tissue is formed within the bone graft itself.
Co-Authors Akhmad Herman Yuwono Akhmad Herman Yuwono Andriyah, Lia Anne Zulfia Arbi Dimyati Badrul Munir, Badrul Bambang Irawan Bustanul Arifin Demas Seto Elfi N Firdiyono Firdiyono Firdiyono, Firdiyono Hanny Hafiar Is Prima Nanda Johny Wahyuadi Soedarsono, Johny Kirman Kirman, Kirman Lalasari, Latifa Hanum Latifa Hanum Lalasari Lia Andriyah Luh Putu Ratna Sundari Marsetio, Aldo Fransiskus Marzuki Silalahi N, Elfi Nurhayati, Neni Octapiani Pribadi, Pancar Muhammad Pudji Untoro Pudji Untoro Rahyussalim Rahyussalim, Rahyussalim Sri Harjanto Sri Harjanto Sugeng Supriadi, Sugeng Tito Winnerson Sitanggang, Tito Winnerson Tjokro Prasetyadi, Tjokro Vika Rizkia