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All Journal Jurnal Kedokteran Brawijaya Majalah Obat Tradisional Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Jurnal Ilmiah Manuntung Jurnal Riset Kefarmasian Indonesia Electrices : Jurnal Otomasi Kelistrikan dan Energi Terbarukan
Supomo Supomo
Akademi Farmasi Samarinda, Samarinda, Kalimantan Timur
Agriculture, Biological Sciences & Forestry Control & Systems Engineering Electrical & Electronics Engineering Energy Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health

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Journal : Jurnal Kedokteran Brawijaya

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Effects of Pulmonary Vascular Resistance Index on Oxygen Saturation in Patients with Atrial Septal Defect Supomo, Supomo
Jurnal Kedokteran Brawijaya Vol 31, No 1 (2020)
Publisher : Fakultas Kedokteran Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (252.058 KB) | DOI: 10.21776/ub.jkb.2020.031.01.13

Abstract

Atrial septal defect (ASD) is a congenital lesion in atrium septum. The lesion may cause pulmonary hypertension due to the high pressure in the right ventricle. This condition leads to cyanosis in ASD patient, but the pathophysiology of cyanosis in ASD patient is still unknown. This study aimed to identify the pathophysiology of cyanosis in ASD patients using the Pulmonary Vascular Resistance index (PVRi). The design of this study was retrospective cohort study. The data used in this study were the results of right heart catheterization procedure taken from forty ASD patient medical records at Dr. Sardjito general hospital. The exclusions criteria were the history of previous vasodilator administration and incomplete medical records. The median age of the patients was 30 (18-55) years old. The mean of the Qp/Qs ratio was 1.210 (0.57-6.33). Optimum oxygen saturation was found in vessel leaving the heart. The PVRi median is 61.98 (-15.58-676.64). The PVRi has a significant correlation with oxygen saturation, except in the right atrium. There is a significant correlation between PVRi and oxygen saturation in various heart chambers. Pathophysiology of cyanosis in ASD patients is central cyanosis.
Co-Authors Basyar, Fredi Eka Siswanto Syamsul Hayatus Sa`adah, Hayatus Musaenah, Musaenah NUR KOMALASARI Said, Bagus Moch sapri sapri Sari, Desy Nur Indah Siswanto, Eka Utami, Hajar Dian Ventyrina, Ine Warnida, Husnul Yullia Sukawati, Yullia