Yukhi Kurniawan
Department of Andrology and Sexology, Faculty of Medicine, Universitas Udayana, Denpasar, Indonesia

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Relationship Between Smoker Male Partner and Intrauterine Insemination Success in Kasih Ibu General Hospital Denpasar Albert Salim; Yukhi Kurniawan; I Gusti Ngurah Pramesemara
Indonesian Andrology and Biomedical Journal Vol. 2 No. 2 (2021): December
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (713.607 KB) | DOI: 10.20473/iabj.v2i2.163

Abstract

Background: Assisted reproductive technology, one of which is intrauterine insemination (IUI) allows infertile couples to get pregnant. The pregnancy success of IUI procedure varies among individuals. Objective: The study aim is to determine whether there is a relationship between smoker male partners and IUI success. Methods: This research is an analytic study with cross-sectional approach conducted at Kasih Ibu General Hospital Denpasar with purposive sampling technique. There are 35 male couples aged 25-50 years who underwent the IUI procedure selected as samples. The research data was gathered from patient's medical records and statistically analyzed using the Chi-Square test. Results: The study found that of the 35 samples, 13 (37.1%) were smokers, whereas 22 (62.9%) male partners were non-smokers. There were 6 (17.1%) samples’ partners who were pregnant after undergoing the IUI procedure, and 29 (82.9%) samples’ partners were not pregnant. It was found that there was no significant relationship between male partner smokers and the success of IUI at Kasih Ibu General Hospital Denpasar (p=0.832). However, in descriptive analysis and relative risk calculation, smoker male partner is less likely to achieve pregnancy than non-smoker’s male partner (RR=0.85). Conclusion: Smoker male partners may not contribute to IUI success. Further studies should be done with a higher number of samples, multicenter, and more controlled risk factors to make it more accurate in determining the relationship.
Relationship Between Waist Circumference and The Event of Andropause in Male Employees in Government Institutions of Badung Regency Anak Agung Ayu Dian Indah Lestari; I Gusti Ngurah Pramesemara; Yukhi Kurniawan
Indonesian Andrology and Biomedical Journal Vol. 2 No. 1 (2021): June
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (542.215 KB) | DOI: 10.20473/iabj.v2i1.37

Abstract

Background: Andropause occurs with slow development and is a physiological process in males. Andropause symptoms arise vary in individuals. One of the factors that influence these symptoms is obesity, especially central obesity with a waist circumference of >90 cm. Objective: The purpose of this study is to show the relationship between waist circumference and the event of andropause. Methods: This research is an analytical study with a cross-sectional study approach conducted in one of the government institutions of Badung Regency, Bali Province. The sampling technique used was purposive sampling. The subjects consisted of 40 male employees at aged around 35-60 years. The research data were obtained from filling out the Androgen Deficiency in Aging Male (ADAM) score questionnaire and direct measurement of waist circumference. The statistical analysis used was the Chi-Square test. Results: The results showed that from 40 subjects, 23 (57.5%) subjects had a waist circumference of >90 cm, and a normal waist circumference of <90 cm in 17 (42.5%) subjects. There were 22 subjects (55.0%) who experienced andropause and 18 (45.0%) subjects who did not experience andropause. It was found that there was a significant relationship between waist circumference and the event of andropause among male employees in government institutions of Badung Regency (p = 0.001, OR = 11.7). Conclusion: The study has found that higher in waist circumference may contribute in the event of andropause. For further studies should takes a higher number of subjects to make it more accurate in wider population.
Relationship Between the Age of Female Partner and the Intrauterine Insemination Success in Rumah Sakit Ibu dan Anak Puri Bunda Denpasar Alycia Madeleine; Yukhi Kurniawan; I Gusti Ngurah Pramesemara
Indonesian Andrology and Biomedical Journal Vol. 3 No. 1 (2022): June
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (414.964 KB) | DOI: 10.20473/iabj.v3i1.35875

Abstract

Infertility is the inability of couples who have regular sexual intercourse without using protection to achieve pregnancy within one year. The prevalence of infertility was 21.3% in Indonesia. Intrauterine Insemination (IUI) is an assisted reproductive technology chosen by infertile couples to have children. Various factors influence the success of IUI. One factor that influences the success of IUI is the female partner’s age. To determine the relationship between the age of female partners and the success of IUI. This study is descriptive-analytical research with the Cross-Sectional method using secondary data obtained from medical records of patients who underwent IUI procedures from January to March 2020 at Rumah Sakit Ibu dan Anak Puri Bunda Denpasar. Total research subjects are 31 patients with an average age of 32 years. Positive pregnancies in female partners aged 25-35 years are 8 patients (33,3%) and female partners aged 35-40 are 1 patient (14.3%). Most patients had secondary infertility with a duration of 1-3 years. There is no relation between the increasing age of female partners and the decreasing success of IUI at Rumah Sakit Ibu dan Anak Puri Bunda Denpasar (p=0,329). But female partners aged 25-35 years tended to have a positive pregnancy 2,333 times higher than female partners aged 35-40 years (RR=2,333; CI 95%: 0,349-15,612).
Relationship Between Body Mass Index and Male Infertility at Kasih Ibu General Hospital Denpasar Amelia Heryanto; I Gusti Ngurah Pramesemara; Yukhi Kurniawan; I Gusti Ayu Widianti
Indonesian Andrology and Biomedical Journal Vol. 3 No. 1 (2022): June
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (395.907 KB) | DOI: 10.20473/iabj.v3i1.35876

Abstract

Infertility can occur in men, characterized by the inability to make pregnancy in the partner. The causes of male infertility are multifactorial, one of which is obesity. Obesity parameter by body mass index >25 kg/m2. This study purposes of determining the relationship between obesity with body mass index measurement and male infertility. This type of research is an analytical cross-sectional study. This research was located at the Kasih Ibu General Hospital Denpasar. Purposive sampling was chosen as the sampling technique. The samples were 50 male patients aged 25-45 years who checked themselves at the Kasih Ibu General Hospital Denpasar between January and December 2020. All research data could be seen from the patient's medical records. The Pearson Chi-Square test was used to analyze the data. The results were 26 subjects (52%) with BMI >25 kg/m2 (obese) and 24 subjects (48%) with BMI <25 kg/m2 (non-obese). About 28 subjects (56%) were infertile, and 22 subjects (44%) were fertile. This study found that body mass index was significantly associated with infertility in male patients at Kasih Ibu General Hospital Denpasar. Obese men had a 2,308 higher risk of infertility than men were not obese (p = 0.002, RR = 2.308 (CI95% 1.262-4.220). The study has found that obesity may contribute to the event of male infertility. For further research should use a larger sample size to make it more accurate in population.  
The Relationship Between Varicocele in Infertile Male and Intrauterine Insemination Success at Rumah Sakit Ibu dan Anak Puri Bunda Denpasar Andhika Bhayangkara Putra Anak Agung Gde; I Gusti Ngurah Pramesemara; Yukhi Kurniawan; I Gusti Ayu Widianti
Indonesian Andrology and Biomedical Journal Vol. 3 No. 2 (2022): December
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/iabj.v3i2.35877

Abstract

Background: Assisted Reproductive Technology (ART), such as intrauterine insemination (IUI), can be an option for infertile couples who are expecting a pregnancy. However, the success of IUI can be influenced by various factors, one of which is varicocele.   Objective: This study aims to determine the association between varicocele and IUI success. Methods: This study is an analytical cross-sectional study using patient medical records. The sample of this study was male patients aged 25-45 years with infertility and undergoing IUI in the period April to June 2021 at Rumah Sakit Ibu dan Anak Puri Bunda Denpasar. The sampling technique used, purposive sampling, was selected based on inclusion and exclusion criteria. Based on the criteria, this study selected 32 samples. Result: From 32 participants, 5 had varicocele (15.6%), and 27  were without varicocele (84.4%). In this study, we found 12 success pregnancy after IUI (37.5%), with 3 participants having varicocele (9.4%) and 9 participants without varicocele (28.1%). The chi-square analysis carried out obtained the results (p>0.05), and the calculation of the relative risk got the result (RR=0.600). Conclusion: This study showed no significant association between varicocele in infertile men and the success of IUI. The RR calculation showed that varicocele was not a risk factor for IUI failure.
Leukospermia in Infertile Men and Successful Intrauterine Insemination at Rumah Sakit Ibu dan Anak Puri Bunda Denpasar Anak Agung Ngurah Perdana Anantadiva; I Gusti Ngurah Pramesemara; Yukhi Kurniawan; I Gusti Ayu Widianti
Indonesian Andrology and Biomedical Journal Vol. 4 No. 1 (2023): June
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/iabj.v4i1.41761

Abstract

Infertility is a condition after a year of regular sexual intercourse, without the use of contraceptives, and ends with the absence of pregnancy. Intrauterine Insemination (IUI) is a procedure that is widely used in fertility clinics and is usually the first treatment option in patients who are experiencing infertility disorders, diagnosis of infertility due to cervical factors, diagnosis of factor infertility in men, and diagnosis of unexplained infertility. the cause. IUI is also a simple, inexpensive, and quite effective infertility treatment. One of the factors that can influence the success of IUI is leukospermia. This study is an analytical study using a cross-sectional design and using medical records of patients diagnosed with infertility, aged from 25 to 45 years, and undergoing IUI procedures from January to June 2022 at the RSIA Puri Bunda Denpasar. The sampling method in this study used a purposive sampling method which was selected based on inclusion and exclusion criteria. In this study, 53 samples were obtained. Of the 53 samples that have been collected, 13 people experienced leukospermia (24.5%), 40 people were non-leukospermic (75.5%). The success of IUI in this study was 17 people (32.1%) consisting of 3 leukospermic (23.1%) and 14 non-leukospermic (35.0%). The results of the Fisher's Exact test obtained, namely the p value = 0.511, it can be concluded that leukospermia with the success of IUI does not have a significant relationship. Calculation of odds ratio (OR) obtained a figure of 1.759 (CI95% 0,423-7,610).
Sperm Agglutination in Infertile Men and The Success Rate of Intrauterine Insemination in Rumah Sakit Ibu dan Anak Puri Bunda Denpasar Anak Agung Sintya Padma Dewi; I Gusti Ngurah Pramesemara; Yukhi Kurniawan; I Gusti Ayu Widianti
Indonesian Andrology and Biomedical Journal Vol. 4 No. 1 (2023): June
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/iabj.v4i1.42110

Abstract

Background: Every human being, especially a married couple, wants children. Obstacles to obtaining children are called infertility. One of the Assisted Reproductive Technology (ART) procedures used for treating infertility is intrauterine insemination (IUI), a non-invasive procedure with affordable costs. The success of IUI is influenced by many factors, one of which is sperm agglutination. Objective: This study determined the relationship between sperm agglutination and the success rate of the IUI procedure. Methods: The study is a descriptive-analytic study with a cross-sectional approach. The sample collection technique uses non-probability. The data used were medical records of male patients diagnosed with infertility, aged 25-45 years, and undergoing IUI procedures at the Rumah Sakit Ibu dan Anak Puri Bunda Denpasar from January to July 2022. Results: Of the 91 samples obtained, 9 people experienced sperm agglutination (9,9%), and 82 people did not experience sperm agglutination (90,1%). The success rate of the IUI procedure was 29 people (31,9%), 1 person (11.1%) experiencing sperm agglutination, and 28 people (34,1%) not experiencing sperm agglutination. Fisher's Exact test carried out has obtained a result (p=0.263). And the value of the odds ratio (OR) obtained=0.241) Conclusion: This study concluded that there is no significant relationship between sperm agglutination in infertile men and the success rate of the IUI procedure. The value of OR showed sperm agglutination is not included in the factors that affect the success rate of IUI. Keywords: Sperm Agglutination, Intrauterine Insemination, Male Infertility