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All Journal Farmasains : Jurnal Farmasi dan Ilmu Kesehatan Medfarm: Jurnal Farmasi dan Kesehatan
Astridani Rizky Putranti
Universitas Surabaya
Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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The Formulation and Evaluation of Facial Wash containing Snow Mushroom (Tremella fuciformis) Extract Astridani Rizky Putranti; Krisyanti Budipramana; Mellynia Fortuna Salim
Farmasains : Jurnal Farmasi dan Ilmu Kesehatan Vol. 7 No. 1 (2022)
Publisher : Universitas Muhammadiyah Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22219/farmasains.v7i1.20063

Abstract

The aims of this study were to determine and evaluate the results of the physicochemical characteristic of snow mushroom (Tremella fuciformis) facial wash, and to determine the acceptability of the snow mushroom (Tremella fuciformis) extract facial wash which has the best physicochemical characteristics. In this study, the extraction of snow mushroom (Tremella fuciformis) used UAE (Ultrasound-Assisted Extraction) and ethanol as solvent with various concentrations, 96% (F1), 75% (F2), and 50% (F3). Furthermore, the extract will be formulated into facial wash and evaluated for physicochemical characteristics. The parameters of physicochemical characteristics include organoleptic, pH, density, viscosity, spreadability, and foamability. The difference in the concentration of ethanol as menstruum of snow fungus (Tremella fuciformis) extraction did not significantly affect the organoleptic composition of facial wash, but it did affect the physicochemical characteristics of facial wash, where higher ethanol concentrations resulted in lower pH, higher density and viscosity, smaller spreadability, and foamability that meets specifications. The results of the evaluation of physicochemical characteristics showed that F1 had the best specifications and continued hedonic testing to determine the acceptability of snow mushroom (Tremella fuciformis) extract facial wash. The results of the hedonic test on F1 showed good acceptance regarding the parameters of appearance, foam, and effects after using facial wash; as well as sufficient acceptability related to aroma and viscosity parameters.
KAJIAN PUSTAKA KRISTAL CAIR (CUBOSOME) SEBAGAI SISTEM PENGHANTARAN OBAT NANOPARTIKEL Astridani Rizky Putranti; Agnes Nuniek Winantari; Ni Made Krisnadewi
MEDFARM: Jurnal Farmasi dan Kesehatan Vol 11 No 1 (2022): MEDFARM: Jurnal Farmasi dan Kesehatan
Publisher : LPPM Akafarma Sunan Giri Ponorogo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.48191/medfarm.v11i1.71

Abstract

Cubosomes are cubic lipid-based delivery systems that can be an option for compounds that have low solubility in water belonging to BCS grades II and IV. The aim of this literature review is to get distinctive characteristics of cubosomes and the entrapment efficiency. Cubosomes was made by lipid (phytantriol, GMO) and added with stabilizer using top-down or bottom-up method. Characterization of cubosomes with instrument such as cryo-TEM (morphology), SAXS (crystalinity), and DLS (size distribution, zeta potential). The characteristic results obtained are cubic with size distribution of 100-500 nm and zeta potential values ±17 mV to 30 mV. As for entrapment efficiency generated ± 90% which indicates most drugs can enter the system.
Co-Authors Agnes Nuniek Winantari Krisyanti Budipramana Mellynia Fortuna Salim Ni Made Krisnadewi