Article Per Year (5 Year)
p-Index From 2019 - 2024
1.745
P-Index
This Author published in this journals
All Journal Jurnal Kedokteran Syiah Kuala MNJ (Malang Neurology Journal) Jurnal Ilmiah Kedokteran Wijaya Kusuma Majalah Kesehatan FKUB Jurnal Berkala Kesehatan Qanun Medika - Medical Journal Faculty of Medicine Muhammadiyah Surabaya Journal of Global Pharma Technology Journal of Community Health and Preventive Medicine
Panji Sananta
Departemen Orthopaedi Dan Traumatologi, Fakultas Kedokteran Universitas Brawijaya
Biochemistry, Genetics & Molecular Biology Environmental Science Health Professions Medicine & Pharmacology Neuroscience Nursing Public Health

Published : 10 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 10 Documents
Search

 1 
KADAR INTERLEUKIN-1β PADA FASE INFLAMASI OSTEOMYELITIS FRAKTUR TULANG FEMUR TIKUS (Rattus norvegicus) DENGAN INTRAMEDULA PINNING DAN GIPS SIRKULAR Sananta, Panji; Sidabutar, Peterson; Inggra, Inggra; Risantoso, Tjuk
Majalah Kesehatan FKUB Vol 4, No 3 (2017): MAJALAH KESEHATAN FAKULTAS KEDOKTERAN
Publisher : Faculty of Medicine Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (356.738 KB) | DOI: 10.21776/ub.majalahkesehatan.2017.004.03.2

Abstract

Osteomyelitis sampai saat ini masih menjadi masalah baik pada usia anak maupun dewasa. Sulitnya deteksi dini menjadikan banyak kasus akut menjadi kronis sehingga semakin sulit penatalaksanaanya. IL-1 memiliki peranan sangat penting dalam proses penyembuhan fraktur. Pada penelitian ini ingin diketahui kadar IL-1b pada fase inflamasi osteomyelitis fraktur tulang femur dengan intramedula pinning dan gips sirkular. Desain penelitian ini adalah eksperimental laboratoris dengan post test only control group design menggunakan hewan coba tikus sebanyak 20 ekor yang terbagi menjadi kelompok infeksi dan non infeksi. Pengukuran kadar IL-1b serum dilakukan pada hari ke-1, ke-3, dan ke-7 dari daerah fraktur tulang femur. Kondisi osteomyelitis dibuat dengan menginjeksikan Staphylococcus aureus sebanyak 106  CFU dengan metode ELISA. Analisis statistik menggunakan uji ANOVA dilanjukan dengan uji Tukey  menunjukkan bahwa kadar IL-1b meningkat signifikan pada hari ke-3 pada kelompok infeksi dibanding kelompok non infeksi (p < 0,01). Dapat disimpulkan bahwa osteomyelitis pada fraktur tulang femur dengan intramedula pinning dan gips sirkular terbukti meningkatkan kadar IL-1b serum.Kata kunci: fraktur femur, IL-1b, osteomyelitis, gips sirkular, intramedula pinning
Osteogenesis imperfecta and bisphosphonate Panji Sananta; Alva Pribadi
Jurnal Kedokteran Syiah Kuala Vol 22, No 1 (2022): Volume 22 Nomor 1 Maret 2022
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/jks.v22i1.21261

Abstract

Osteogenesis Imperfecta (OI) is defined as genetic disorders presented by various clinical presentations, such as bone deformities, abnormalities in dental structure, deafness, blue sclera, growth retardation, and ligament laxity. Most OI patients have a mutation in collagen type I alpha chains genes, COL1A1 and COL1A2. All those genes are expressed in osteoblasts and mostly responsible for the direct metabolism of collagen type I. Bisphosphonates (BPs), as potent antiresorptive agents, inhibit bone resorption through direct actions in the osteoclasts. They cut the excessive turnover rate and prevent bone tissue loss. The selection of BP regimens for OI patients is still a significant obstacle due to the lack of standardization of therapy and the lack of published evidence to determine the most appropriate type for different OI patients. The current use of BP and its benefit in OI are discussed in this review.
Age and Knee Osteoarthritis Severity Relationship in Indonesian Secondary Referral Hospital Panji Sananta; Haidar Abror Firladi; Dhelya Widasmara; Eka Noviya Fuzianingsih
Jurnal Berkala Kesehatan Vol 8, No 2 (2022): JURNAL BERKALA KESEHATAN
Publisher : Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jbk.v8i2.14608

Abstract

Osteoarthritis is a chronic joint disease that causes pain, disability, and loss of function. More than 80% of cases of osteoarthritis affect the knee joint. The exact cause of knee osteoarthritis is still unknown, but it is generally associated with aging and obesity. This study aimed to determine the relationship between age and the severity of knee osteoarthritis. This research used a cross-sectional study involving patients who suffered from knee osteoarthritis. Data on gender and the severity of osteoarthritis was collected from medical records. The severity of knee osteoarthritis was assessed using the Kellgren-Lawrence system. The data was analyzed using the Spearman correlation. There were 3 patients (8.1%) in the category of late adulthood, 7 patients (18.9%) in the middle-aged category, 13 patients (35.1%) in the early-onset elderly category, and 14 patients (37.8%) in the elderly. Seven patients (23.7%) suffered from osteoarthritis grade 1, 13 patients (35.1%) had grade 2, 16 patients (43.2%) had grade 3, and one patient had grade 4. The Spearman test showed that there was no significant relationship (p>0.05) between age and the severity of knee osteoarthritis. According to the study's findings, there was no correlation between age and the severity of knee osteoarthritis in women and men patients at Baptis Hospital, Batu City.
Musculoskeletal Infections In Pediatric Patients at Saiful Anwar General Hospital: Observation for 5 Years Panji Sananta; Satria Prabawa Perkasa Suhaedy; Felix Cendikiawan; Muhammad Abduh; Alva Pribadi
Jurnal Berkala Kesehatan Vol 7, No 2 (2021): JURNAL BERKALA KESEHATAN
Publisher : Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jbk.v7i2.9525

Abstract

Musculoskeletal infection in pediatrics is a disorder that can cause significant disability. Follow-up evaluation is mandatory to ensure good long-term results. However, there is no data regarding this in Indonesia. The purpose of this study was to describe the epidemiology of musculoskeletal infections in pediatrics in Indonesia. This study is an observational epidemiological study of all pediatric musculoskeletal infection patients at Saiful Anwar Hospital Malang, Indonesia. All data were obtained from the database of the Department of Orthopedics and Traumatology of Saiful Anwar Hospital for the 2016-2020 period. A total of 71 patients were included in this study. The data collected were age, gender, diagnosis, anatomic location, treatment, and outcome. There were 48 (67.60%) male and 23 (32.39%) female patients in our study. The most frequent site of infection was the lower extremities (57.75%), followed by the spine (35.21%). In this study, the highest incidence occurred in children (6-12 years) followed by adolescents (12-18 years). This study also showed similar findings to other studies for the site of infection where the most common infection involved the lower extremities. Multidisciplinary treatment must be undertaken to reach an accurate diagnosis, determine the need for surgery, and monitor response to treatment.
Association between the degree of Osteoarthritis and pain level of patients at Baptist Hospital, Batu City Panji Sananta; Hansel Hansel; Dhelya Widasmara; Eka Noviya Fuzianingsih
Qanun Medika - Jurnal Kedokteran FK UMSurabaya Vol 7 No 1 (2023): Qanun Medika Vol 07 No 01 January 2023
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jqm.v7i1.13483

Abstract

Osteoarthritis is a chronic disease characterized by the destruction of cartilage in the joints, causing stiffness, pain, and impaired movement. The condition most commonly affects the joints of the knees, hands, feet, spine, and often the shoulders and hips. Knee osteoarthritis is a major public health problem that causes chronic pain and reduces physical function and quality of life. This study determined the relationship between the degree of Osteoarthritis and the pain level in patients at Baptist Hospital, Batu City. This research used a cross-sectional study with 31 respondents. Data collection was conducted directly using the WOMAC (Western Ontario and McMaster Universities Osteoarthritis Index) questionnaire, modified in Indonesian. To determine the grade of Osteoarthritis using the Kellgren-Lawrence system. The results showed that out of 31 respondents, there were nine patients (29%) who had grade 1 osteoarthritis, 12 patients (38.7%) had grade 2, and 10 patients (32.3%) had grade 3. There were 22 patients (71%) who had a mild pain level, four patients (13%) had a moderate level, and five patients (16%) had a severe pain level. The Spearman correlation test showed no significant relationship (p>0.05) between the degree of Osteoarthritis and the level of pain in patients. This study concludes that there was no relationship between the increasing degree of Osteoarthritis and the level of pain.
Insilico and Electron Microscope Study about Attachment of Mesenchymal Stem Cell Derived from Stromal Vascular Fraction to Scaffold (Bovine Bone Cancellous, Hydroxyapatite-Calcium Sulphate, Calcium Phosphate) Panji Sananta
Journal of Global Pharma Technology Volume 11 Issue 6.
Publisher : Journal of Global Pharma Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (533.679 KB)

Abstract

Objective: Insilico study using molecular docking with Hex had already surpassed all of the other previous approach in assessment of molecular binding to scaffold. The combination of insilico study to investigate the molecular binding to scaffold and electron microscope to assess the population density of adipocyte derivative stem cells by measuring the number of cluster cells could show the inter cell communication between adipocyte derived stem cell and scaffold. The aim of this study is to prove the attachment of mesenchymal stem cell (MSC) from stromal vascular fraction (SVF) to scaffold.Methods: The research is true experimental research using molecular docking with HEX version 8.0. Electron microscope used to measure the density and number of cluster cells of adipocyte derivative stem cells.Results: The strongest bound to scaffold is between MSC from SVF to hydroxyapatite in both receptor which was Integrin Alpha V to Hydroxyapatite which need a total energy of -89.24 (J/Mol) and Integrin Beta 2 to Hydroxyapatite which need a total energy of -177.8 (J/Mol). The highest impact obtained from hydroxyapatite-calcium phosphate with an average value of 12.66 cluster cells counting per 100 µm2 scaffold material observed by electron microscope.Conclusion: This study showed that MSC from SVF could attach to scaffold with stronger binding between Integrin Alpha V and Integrin Beta 2 to hydroxyapatite. From microscope electron study we can prove that MSC can make a cluster cell in those scaffolds with hydroxyapatite-calcium sulphate having the biggest cluster cell counting.Keywords: Hydroxyapatite; Integrin Alpha V; Integrin Beta 2; Mesenchymal stem cell; Scanning electron microscope; Stromal vascular fraction.
CORRELATION BETWEEN VITAMIN D DEFICIENCY AND LOW BODY HEIGHT Panji Sananta; Aristoteles Aristoteles; Fauzan Yusman; Satrio Bangun Negoro; Muhammad Hilman Bimadi; Felix Cendikiawan
Journal of Community Health and Preventive Medicine Vol. 1 No. 1 (2021): JOCHAPM Vol. 1 No. 1 2021
Publisher : Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1842.706 KB) | DOI: 10.21776/ub.jochapm.2021.001.01.3

Abstract

The average height of the Indonesians population has increased a few centimeters for the last 50 years, although Indonesians are short. However, a secular trend in height was still unclear. Currently, the Indonesians adult population is averagely shorter than the modern World Health Organization (WHO) reference males and females. Thus, when comparing the height of Indonesian children with several growth measurements, a significant portion of the children is below the critical limit. This review aimed to discuss the correlation between deficiency vitamin D and low body height
Body Mass Index and Knee Osteoarthritis: A Retrospective Cross-Sectional Study in Baptis Hospital, Batu City Panji - Sananta; Wildan Faza Pratama; Dhelya - Widasmara; Eka Noviya Fuzianingsih
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 12, No 1 (2023): March 2023
Publisher : Universitas Wijaya Kusuma Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30742/jikw.v12i1.2595

Abstract

Osteoarthritis is a chronic global and musculoskeletal disorder. This disease is associated with reduced articular cartilage integrity. The most commonly affected joint is the knee, followed by the hand and the hip. Knee osteoarthritis is associated with aging, obesity, articular cartilage, fatigue, trauma, and congenital joint deformities. Excess body weight is a factor that will exacerbate osteoarthritis. There are still meta-analysis studies involving cohort and case-control studies on osteoarthritis and body mass index (BMI) available, but the relationship between the two variables is still not assessed quantitatively. In addition, research on knee osteoarthritis and BMI is still limited, particularly at Baptis Hospital, where it has never been done. As a result, this study was carried out to determine the relationship between BMI and the degree of knee osteoarthritis. This retrospective cross-sectional study involved 33 patients who suffered from knee osteoarthritis. Data were collected from medical records, and the Kellgren-Lawrence system to assess the degree of knee osteoarthritis based on radiology findings. A total of 7 patients (21.2%) suffered from osteoarthritis grade 1, 10 patients (30.3%) had degree 2, 15 patients (45.5%) had degree 3, and one patient had degree 4. The Spearman correlation test showed that there was no significant relationship (p>0.05). So, it can be concluded from this study that there was no correlation between BMI and the degree of knee osteoarthritis patients at Baptis Hospital, Batu City.
THE ROLE OF INTRAOPERATIVE NEUROPHYSIOLOGIC MONITORING TO ENHANCE SUCCESSFUL ORTHOPEDIC SURGERY Panji Sananta; Anindita Eka Pramana Wijaya; Marvin Anthony Putera
MNJ (Malang Neurology Journal) Vol. 8 No. 1 (2022): January
Publisher : PERDOSSI (Perhimpunan Dokter Spesialis Saraf Indonesia Cabang Malang) - Indonesian Neurological Association Branch of Malang cooperated with Neurology Residency Program, Faculty of Medicine Brawijaya University, Malang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.mnj.2022.008.01.8

Abstract

One of the main advance in orthopaedic surgery domain has a goal to investigates the safest and harmless method in surgical procedures. Less complications means a better outcome of surgery. One of the commonest risks at orthopaedic surgery is central and peripheral nerve injury. The modality of Intraoperative Neurophysiologic Monitoring (IONM) which act to limit the risk of nerve injury during operative procedure through the evaluation of nerve integrity and function enable the surgeon to decrease injury to the nerve associated with orthopaedic surgical procedure in the operating room. This article aims to explain and describe the latest modality of IONM, its basic concept and its function at surgery. The last part of the article discussed about orthopaedic surgical techniques which use IONM. The authors hope that this article will enhance the knowledge of all the readers about IONM. This article was written based on literature study searched at Google Scholar, Medline and PubMed. The references were taken from a relatively up to date study ranging from 2013-2018. The article was selected according to the authors inclusion criteria and six articles was chosen as the references for this review. As a conclusion, IONM has an important role to increase successful rate of surgery through minimizing nerve injury risk during surgical procedure.
Treatment in transient synovitis cases: A review Panji - Sananta; Fernaldhi - Anggadha; Eka Noviya Fuzianingsih
Qanun Medika - Jurnal Kedokteran FK UMSurabaya Vol 8 No 01 (2024): Qanun Medika Vol 08 No 01 January 2024
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jqm.v8i01.17967

Abstract

Inflammation of the synovial membrane of a joint is a common symptom of transient synovitis (TS), which is the medical term for a condition that leads to hip discomfort in juvenile patients.  The estimated annual incidence of TS is 0.2%, and the risk of developing the disease over one's lifetime is 3%.  Unfortunately, the specific pathophysiology of TS is still unclear.  Therefore, the particular treatment is still debatable.  There are several methods of treating TS, starting with bed rest in the hospital and using analgesics, steroids, skin traction, and joint aspiration.  Most of the time, transient synovitis is a self-limiting condition that heals independently and is managed conservatively by monitoring and rest.  Several medical therapy options, including analgesics, NSAIDs, and corticosteroids, speed up healing.  On the other hand, skin traction is also reported to provide beneficial therapeutic effects for TS patients.  Thus, with many therapeutic options, TS's "golden" management still needs further study.
Co-Authors Alva Pribadi Alva Pribadi Anindita Eka Pramana Wijaya Aristoteles Aristoteles Dhelya Widasmara Eka Noviya Fuzianingsih Eka Noviya Fuzianingsih Fauzan Yusman Felix Cendikiawan Felix Cendikiawan Fernaldhi - Anggadha Haidar Abror Firladi Hansel Hansel Inggra Inggra, Inggra Marvin Anthony Putera Muhammad Abduh Muhammad Hilman Bimadi Peterson Sidabutar, Peterson Satria Prabawa Perkasa Suhaedy Satrio Bangun Negoro Tjuk Risantoso, Tjuk Wildan Faza Pratama