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All Journal Jurnal Biosains Pascasarjana Jaringan Laboratorium Medis E-Amal: Jurnal Pengabdian Kepada Masyarakat
Rachmad Bayu Kuncara
Poltekkes Kemenkes Semarang
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Computer Science & IT Dentistry Economics, Econometrics & Finance Education Health Professions Immunology & microbiology Public Health

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The Effect Of Various Sun Time Under Exposure To Ultraviolet Light Of The Sun On Interleukin 10 Cytokine Rachmad Bayu Kuncara
Jurnal Biosains Pascasarjana Vol. 24 No. 1 (2022): VOL 24, NO 1 (2022): JURNAL BIOSAINS PASCASARJANA
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jbp.v24i1.2022.29-33

Abstract

Sunbathing activities are often found to occur during the severe acute respiratory syndrome coronavirus 2 (SARS CoV2) pandemic that causes Corona Virus Disease 2019 (COVID 19). IL-10 is an inhibitory cytokine for macrophages and dendritic cells that play a role in controlling non-specific and cellular immune reactions. The purpose of this study was to explain the immunosuppression by the cytokine interleukin 10 which is often found to occur due to sun exposure. This research method is an experimental study with a completely randomized design (CRD). The research design used was a randomized post test only control group design. Data were analyzed using the Kruskal Wallis test with statistical test results obtained p value 0.550 (> 0.05) meaning there was no difference in the levels of cytokine interleukin 10 in each treatment group.
Perbedaan Kadar Vitamin D3 pada Penderita Tuberkulosis Paru Sebelum dan Sesudah Satu Bulan Terapi Obat Anti Tuberkulosis Rachmad Bayu Kuncara; Dewina Zumrotin Najiah
Jaringan Laboratorium Medis Vol 6, No 1 (2024): May 2024
Publisher : Poltekkes Kemenkes Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31983/jlm.v6i1.11379

Abstract

Pulmonary tuberculosis is an infectious disease caused by infection with the bacteria Mycobacterium tuberculosis. Patients diagnosed with pulmonary tuberculosis will receive Anti-Tuberculosis Drug (OAT) therapy for six months. In the first two months or what is called the intensive phase, the patient will be given a combination of OAT in the form of rifampicin, isoniazid, ethambutol and pyrazinamide. Several types of anti-tuberculosis drugs have the potential to affect vitamin D3 metabolism, either by interfering with absorption, metabolism or changing the action of vitamin D3. The long-term treatment process for pulmonary tuberculosis also results in a decrease in vitamin D3 levels in the blood. This study aims to determine the difference in vitamin D3 levels in pulmonary tuberculosis sufferers before and after one month of anti-tuberculosis drug therapy. This type of research is descriptive observational with a prospective cohort design without comparison. The total sample was 16 newly diagnosed pulmonary tuberculosis sufferers at the Bangetayu, Kedungmundu and Tlogosari Wetan Health Centers, Semarang City. Vitamin D3 levels in serum samples were examined using the ELISA method. The mean vitamin D3 level before OAT therapy was 19.00 ± 10.45 ng/mL, the level decreased after OAT therapy, namely 18.51 ± 4.74 ng/mL. These results indicate that administration of anti-tuberculosis drugs may have an effect on vitamin levels.
PELATIHAN TEKNIK PENGAMBILAN, PENGEPAKAN DAN PENGIRIMAN SPESIMEN DAHAK (SPUTUM) UNTUK DIAGNOSIS TUBERKULOSIS BAGI KADER KESEHATAN DI KELURAHAN SENDANG MULYO Rachmad Bayu Kuncara; Ichsan Hadipranoto; Roni Afriansya; Wiwit Sulistyasmi
E-Amal: Jurnal Pengabdian Kepada Masyarakat Vol 4 No 2: Mei-Agustus
Publisher : LP2M STP Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47492/eamal.v4i2.3213

Abstract

Tuberkulosis merupakan penyakit menular yang disebabkan oleh bakteri Mycobacterium tuberculosis complex (MTBC). Strategi DOTS adalah pengawasan langsung pengobatan jangka pendek dengan keharusan setiap pengelola program tuberkulosis untuk memfokuskan perhatian (direct attention) dalam usaha menemukan penderita dengan pemeriksaan mikroskop. Tujuan dari kegiatan ini adalah peningkatan pengetahuan kader tentang teknik pengambilan, pengepakan dan pengiriman spesimen dahak (sputum) untuk diagnosis tuberkulosis bagi kader kesehatan di Kelurahan Sendang Mulyo. Metode: melakukan intervensi dengan meningkatkan pengetahuan kader kesehatan dengan memberikan penyuluhan teknik pengambilan, pengepakan dan pengiriman spesimen dahak. Hasil: terjadi peningkatan pengetahuan kader sebesar 70% dalam mengetahui tentang teknik pengambilan, pengepakan dan pengiriman spesimen dahak.
Co-Authors Dewina Zumrotin Najiah Ichsan Hadipranoto Roni Afriansya Wiwit Sulistyasmi