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All Journal Prosiding Semnastek Indonesian Journal of Chemical Science Praeparandi : Jurnal Farmasi dan Sains Jurnal Kesehatan Mahardika
Rizkita, Aden Dhana
STIKes Bogor Husada
Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Physics Public Health

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Journal : Indonesian Journal of Chemical Science

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Isolasi dan Uji Antibakteri Minyak Daun Sirih Hijau dan Merah Terhadap Streptococcus mutans. Rizkita, Aden Dhana; Cahyono, Edy; Mursiti, Sri
Indonesian Journal of Chemical Science Vol 6 No 3 (2017)
Publisher : Indonesian Journal of Chemical Science

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Abstract

The purpose of this research is to identify the chemical content and compare the antibacterial effect of Piper betle L and Piper crocatum R oil against Streptococcus mutan. Betel oil is made at 100%, 75%, 50%, 25% concentration and amoxicillin 0.2% as positive control and propylene glycol as negative control. The research method started with oil isolation using distillation of steam and water then identified the content using GC-MS. Antibacterial activity was tested against Streptococcus mutans by disc diffusion method. The results of this research indicate that Piper betle L and Piper crocatum R oil contains terpenoid group compounds. After being characterized using GC-MS, betel oil contains 5 major active compounds that have antibacterial activity that is Sabinene, Myrsene, Camphene, Germacrene and β - Chariophillene. Piper betle oil has better antibacterial properties than Piper crocatum oil with clear zone reaches 10.5 mm while Piper crocatum oil is 7.1 mm.
Effect Of The Extraction Methods On The Identification Of Caffeine In The Extract Of Dragon Fruit Peel Reza pratama saputra; Nurlita Julianti; Azhari Firmansyah; Rhamal Amir; Aden Dhana Rizkita; Sintia Ayu Dewi
Indonesian Journal of Chemical Science Vol 12 No 3 (2023)
Publisher : Universitas Negeri Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15294/ijcs.v12i3.75304

Abstract

Dragon fruit is a fruit that is abundantly available in Indonesia. Dragon fruit peel of Hylocereus sp. has become an increasingly popular natural ingredient in the food and beverage industry as it contains rich nutrients that can improve heart health, maintain healthy skin, support weight loss, boost our immune system, and make the body refreshed, including bioactive compounds such as alkaloids. The aim of this study was to identify the most effective extraction method in isolating caffeine compounds from dragon fruit peels. The methods used were maceration, percolation, reflux and fractionation extraction methods. Then for analysis using chromatography method KLT plate Silica Gel GF 254 and compound analysis using HPLC with flow rate of 2 ml/min, pump pressure 75 kgf/cm2, oven temperature 45o C, maximum temperature 85o C, wavelength 275 nm and isocratic eluent flow mode. Based on the research that has been done, it can be concluded that to determine the content of compounds in dragon fruit peel can be done by maceration, percolation and reflux methods. There is caffein at a retention time of 0.7 minutes
Co-Authors Anis Herliyanti Antan Saldaw Arzanto, Adi Wahyu Ayu Andini Rizki Lestari Rohman Azhari Firmansyah Chaidir Chaidir Dewi, Sintia Ayu Dyan Septyaningsih Hardjono HP, Dyan Septyaningsih Edy Cahyono Emas Agus Prastyo Wibowo, Emas Agus Prastyo Ika Sri Hardyanti, Ika Sri Ilham Maulana Isni Nurani, Isni Kon Yohanes Lintang Tri Ananda Maulana, Iham Maulana, Khoironni Devi Muhammad Rafi Hafidz Nisa Alwia Nisa Sri Wahyuni Nurlita Julianti Rahmadhani Tyas Reza Pratama Saputra Rhamal Amir Risma Eka Putri Selay Rochjana, Anna Uswatun Hasanah S Mursiti Shelly Siti Nour Baety Silfia ismiati Sintia Ayu Dewi Syahrul Syah Gibran Yuda Maulidian