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All Journal Nutriology: Jurnal Pangan, Gizi, Kesehatan Indonesian Archives of Biomedical Research (InABR)
Ni Made Wiasty Sukanty
Unknown Affiliation
Biochemistry, Genetics & Molecular Biology Medicine & Pharmacology Public Health

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The role and regulation of FOXO1 in carbohydrate metabolism and its targeting in metabolic diseases Ani Retno Prijanti; Ni Made Wiasty Sukanty
Indonesian Archives and Biomedical Sciences Vol 1 No 2 (2021): Indonesian Archives of Biomedical Research (InABR). 1(2): 2021
Publisher : Konsorsium Ilmu Biomedik Indonesia (KIBI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (145.708 KB) | DOI: 10.55392/indarcbiores.v1i2.8

Abstract

Carbohydrate is the first energy source used in metabolic processes. Failure in carbohydrate metabolism can cause metabolic diseases, and many studies are focused on its therapy. Until now, there is no specific therapy approved. Despite that, one of the main alternatives is regarding the involvement of FOXO1 protein in metabolic disease progress. As a transcription factor for gluconeogenesis genes, FOXO1 can increase blood glucose levels. It also involves various signaling pathways in carbohydrate metabolisms such as PI3K/Akt and PKA in which many proteins act as FOXO1 regulators through posttranslational modification. The vital role of FOXO1 in carbohydrate metabolism provides an opportunity to make FOXO1 the main target of metabolic disease therapy. Various proteins and natural compounds can either directly or indirectly regulate FOXO1 activity. It can be an option to be used to control blood glucose levels by targeting FOXO1
Hubungan Tingkat Pengetahuan Ibu Tentang Asupan Protein dengan Kejadian Stunting pada Balita Anggun Sukma Azani; Wayan Canny Naktiany; Ni Made Wiasty Sukanty
Nutriology : Jurnal Pangan,Gizi,Kesehatan Vol 4 No 2 (2023): Oktober 2023
Publisher : Program Studi Gizi, Universitas Bumigora

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30812/nutriology.v4i2.3253

Abstract

ABSTRACT HUBUNGAN TINGKAT PENGETAHUAN IBU TENTANG ASUPAN PROTEIN DENGAN KEJADIAN STUNTING PADA BALITA DI WILAYAH KERJA PUSKESMAS LINGSAR Anggun Sukma Azani Background: Toddlers are one of the age groups that are prone to nutritional problems. One of the nutritional problems that often occurs in toddlers is stunting. Stunting is a chronic malnutriyion in toddlers that causes children to be too short of children of the same age. Objective: The purpose of this study was to determine the relationship between the level of maternal knowledge about protein intake with the incidence of stunting in toddlers in the Lingsar Health Center work area. Method: The method used in this study is a type descriptive analytic observational research with a cross sectional approach. The population in this study was all stunted toddlers aged 24-59 months in Batu Mekar village, totaling 153 children. The sampling technique in this study was simple random sampling technique with a sample of 65 respondents based on the calculation results using the Lemeshow formula. Data analysis using spearman correlation test. Research Results: The results showed that there was a relationship between the mother’s level of knowledge about protein intake (p = 0.001), there was no relationship between maternal education (p = 0.671), there was no relationship between maternal work (p = 0.060), there was no relationship between maternal age (p = 0.509) and the incidence of stunting in the Lingsar Health Center work area. Conclusion: The conclusion in this study is that there is a significant relationship between the level of mother’s knowledge about protein intake and the incidence of stunting in toddlers in the Lingsar Health Center work area. Keywords: Protein Intake, Toddlers, Mother Knowledge, Stunting
Co-Authors Anggun Sukma Azani Ani Retno Prijanti Wayan Canny Naktiany