Elvioza Elvioza
Department of Ophthalmology, Faculty of Medicine, Indonesia University Cipto Mangunkusumo Hospital, Jakarta

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Various Tamponade in Surgery for Retinal Detachment Associated with Proliferative Vitreoretinopathy Faraby Martha; Andi A Victor; Elvioza Elvioza; Ari Djatikusumo; Gitalisa A Andayani; Anggun R Yudantha
Majalah Oftalmologi Indonesia Vol 41 No 2 (2015): Ophthalmologica Indonesiana
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (508.061 KB) | DOI: 10.35749/journal.v41i2.24

Abstract

Background: To review the literature and report relative efficacy and safety of various tamponade agents used with surgery for rhegmatogenous retinal detachment (RRD) complicated by proliferative vitreoretinopathy (PVR) regarding functional success rate, anatomical success rate, and adverse effects. Methods: We searched articles from PubMed and Clinical Key database starting from the year of 1990 to November 2014. Information needed from all articles were extracted into data extraction sheet. We reviewed the efficacy of both tamponade agents regarding the postoperative visual acuity, macular attachment, and adverse effect. Results: Eight articles were included after fulfilling inclusion and exclusion criteria. Our analysis showed all studies shows an increasing visual acuity and percentage of macular attachment postoperatively of all type tamponade agents. Functional and anatomical success rate of Sulfur hexafluoride gas (SF6) was high in study with PVR stage B or less (94-98%). In patient with complex or recurrent RD associated with PVR, silicone oil had a better functional success (51% vs 32.5%) and better anatomical success (80% vs 60%) than SF6 gas. The anatomical success rate also higher in C3F8 than in SF6 group (73.9% vs 57.5% respectively). Functional and anatomical success rate of HSO as tamponade was high in patients with a severe PVR located mainly in the inferior quadrants (92.3%).Conclusion: As tamponade agents, C3F8 and silicone oil appear to have more visual and anatomic advantages over SF6 in participants with complex or recurrent RD associated with PVR. Silicone oil was better than C3F8 gas to obtain final visual and anatomic successs in patient with recurrent RD associated with higher grade PVR. Heavy silicone oil would be useful in particular cases complicated by recurrent inferior RD with PVR. Retinal redetachment, glaucoma, cataract, hypotony and keratopathy were reported in both gases and silicone group. Keywords: Tamponade in retinal detachment surgery, SF6, C3F8, silicon oil, and heavy silicone oil
Comparison of Laser Photocoagulation Using 810 nm with 20 ms and 100 ms Duration on the Progression of Neovascularization in Proliferative Diabetic Retinopathy Muhammad Yusran; Elvioza Elvioza; Ari Djatikusumo; Rossalyn Sandra Andrisa
Majalah Oftalmologi Indonesia Vol 41 No 2 (2015): Ophthalmologica Indonesiana
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (278.704 KB) | DOI: 10.35749/journal.v41i2.29

Abstract

Background: The aim of this study was to compare the effectiveness of laser photocoagulation 810- nm with 20 ms and 100 ms duration to prevent the progression of proliferative diabetic retinopathy. Method: This study was prospective double blind randomized clinical trial. Twenty-eight participants who met the inclusion criteria divided into two groups to undergo laser photocoagulation by using 810 nm lasers. One group received 100 ms duration and the other received 20 ms duration. Grade 3 burns with a 200 μm spot sized were placed with both parameters. The progression of PDR was evaluated in two months follow up by using seven fields’ fundus photographs. Fluence, power and visual acuity were compared in this study. Result: Twenty five subjects completed the two months follow up. The proportion of non-progressive PDR in 100 ms group was 75.0% and in 20 ms was 76.9% (p=1.000). The power in 20 ms group increased twice than 100 ms group (1000 vs. 500 mW; p=0.000). The median fluence in 20 ms group was less than 100 ms group (6.36 vs. 15.91 J/cm2; p=0.000). Improvement of visual acuity in 20 ms and 100 ms was comparable (23.1% vs. 33,3%; p=1.000). Conclusion: The 20 ms duration showed similar result in preventing the progression of PDR compared to 100 ms duration. Keywords: Proliferative diabetic retinopathy, laser photocoagulation, diode 810 nm
Comparison of Peripapillary Retinal Nerve Fiber Layer (RNFL) Thickness between the Normal and Glaucoma Eyes with the Same Vertical Cup Disc Ratio (CDR) using Optical Coherence Tomography (OCT) Ni Gusti Ari Ayu Raiasih; Elvioza Elvioza; Virna Dwi Oktariana; Joedo Prihartono
Majalah Oftalmologi Indonesia Vol 41 No 3 (2015): Ophthalmologica Indonesiana
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (328.226 KB) | DOI: 10.35749/journal.v41i3.44

Abstract

Background: Glaucoma is a disease that belongs to a group of neurodegenerative diseases, such as impaired visual field and optic neuropathy with progressive damage to the optic nerve and retinal nerve fiber layer (RNFL) which is caused by the loss of ganglion cells and axon of the optic. Changes in the optic nerve and RNFL may occur prior to the abnormalities of the visual field nerves. Currently, the visual field examination should be performed to diagnose glaucoma but with patient-subjective result. Before it is detectable, visual field abnormalities are likely going to lose its ganglion cells by 40%. The purpose of this study was to assess and compare the peripapillary retinal nerve fiber layer (RNFL) between the normal and glaucoma eyes with vertical cup disc ratio (CDR) 0.4 to 0.7 in eye clinic Cipto Mangunkusumo Hospital (RSCM) Kirana. Methods: A total of 40 eyes of normal group and 34 eyes of glaucoma following Humphrey field analyzer examination and Optical Coherence Tomography (OCT) were evaluated. Peripapillary RNFL thickness between normal and glaucoma eyes were analyzed and compared each other. Eyes of glaucoma group then were grouped into early-stage glaucoma, according to the criteria in the initial stages of the examination results of Humphrey field analyzer. Result of peripapillary RNFL thickness was analyzed to get a cut off value. Results: Peripapillary RNFL thickness in the normal group with vertical CDR 0.4 to 0.7 was 111.3±9.8 μm to 118.0±3.0 μm, and glaucoma groups with vertical CDR 0.4 to 0.7 was 105.6±12.6 μm to 113.7±6.1 μm. Retinal nerve fiber layer thickness in normal group compared to glaucoma group in the superior quadrant, inferior, nasal, temporal and average on CDR 0.4 to 0.7 was not statistically significant (p>0.05), except on vertical CDR 0.6 average peripapillary RNFL (p<0.05). Cut off value of peripapillary RNFL in superior quadrant was 164 μm, inferior 169.5 μm, nasal 82.5 μm, temporal 73.5 μm and average 111.8 μm. Conclusion: There was no difference in changes of peripapillary RNFL along with the progression of vertical CDR but clinically, peripapillary RFNL thickness in glaucoma group is thinner than that of normal group with the same vertical CDR except in temporal quadrant. Keywords: Retinal nerve fiber layer (RNFL), cup disc ratio (CDR), optical coherence tomography (OCT)
Various Tamponade in Surgery for Retinal Detachment Associated with Proliferative Vitreoretinopathy Faraby Martha; Andi A Victor; Elvioza Elvioza; Ari Djatikusumo; Gitalisa A Andayani; Anggun R Yudantha
Majalah Oftalmologi Indonesia Vol 41 No 2 (2015): Ophthalmologica Indonesiana
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/journal.v41i2.24

Abstract

Background: To review the literature and report relative efficacy and safety of various tamponade agents used with surgery for rhegmatogenous retinal detachment (RRD) complicated by proliferative vitreoretinopathy (PVR) regarding functional success rate, anatomical success rate, and adverse effects. Methods: We searched articles from PubMed and Clinical Key database starting from the year of 1990 to November 2014. Information needed from all articles were extracted into data extraction sheet. We reviewed the efficacy of both tamponade agents regarding the postoperative visual acuity, macular attachment, and adverse effect. Results: Eight articles were included after fulfilling inclusion and exclusion criteria. Our analysis showed all studies shows an increasing visual acuity and percentage of macular attachment postoperatively of all type tamponade agents. Functional and anatomical success rate of Sulfur hexafluoride gas (SF6) was high in study with PVR stage B or less (94-98%). In patient with complex or recurrent RD associated with PVR, silicone oil had a better functional success (51% vs 32.5%) and better anatomical success (80% vs 60%) than SF6 gas. The anatomical success rate also higher in C3F8 than in SF6 group (73.9% vs 57.5% respectively). Functional and anatomical success rate of HSO as tamponade was high in patients with a severe PVR located mainly in the inferior quadrants (92.3%).Conclusion: As tamponade agents, C3F8 and silicone oil appear to have more visual and anatomic advantages over SF6 in participants with complex or recurrent RD associated with PVR. Silicone oil was better than C3F8 gas to obtain final visual and anatomic successs in patient with recurrent RD associated with higher grade PVR. Heavy silicone oil would be useful in particular cases complicated by recurrent inferior RD with PVR. Retinal redetachment, glaucoma, cataract, hypotony and keratopathy were reported in both gases and silicone group. Keywords: Tamponade in retinal detachment surgery, SF6, C3F8, silicon oil, and heavy silicone oil
Comparison of Laser Photocoagulation Using 810 nm with 20 ms and 100 ms Duration on the Progression of Neovascularization in Proliferative Diabetic Retinopathy Muhammad Yusran; Elvioza Elvioza; Ari Djatikusumo; Rossalyn Sandra Andrisa
Majalah Oftalmologi Indonesia Vol 41 No 2 (2015): Ophthalmologica Indonesiana
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/journal.v41i2.29

Abstract

Background: The aim of this study was to compare the effectiveness of laser photocoagulation 810- nm with 20 ms and 100 ms duration to prevent the progression of proliferative diabetic retinopathy. Method: This study was prospective double blind randomized clinical trial. Twenty-eight participants who met the inclusion criteria divided into two groups to undergo laser photocoagulation by using 810 nm lasers. One group received 100 ms duration and the other received 20 ms duration. Grade 3 burns with a 200 μm spot sized were placed with both parameters. The progression of PDR was evaluated in two months follow up by using seven fields’ fundus photographs. Fluence, power and visual acuity were compared in this study. Result: Twenty five subjects completed the two months follow up. The proportion of non-progressive PDR in 100 ms group was 75.0% and in 20 ms was 76.9% (p=1.000). The power in 20 ms group increased twice than 100 ms group (1000 vs. 500 mW; p=0.000). The median fluence in 20 ms group was less than 100 ms group (6.36 vs. 15.91 J/cm2; p=0.000). Improvement of visual acuity in 20 ms and 100 ms was comparable (23.1% vs. 33,3%; p=1.000). Conclusion: The 20 ms duration showed similar result in preventing the progression of PDR compared to 100 ms duration. Keywords: Proliferative diabetic retinopathy, laser photocoagulation, diode 810 nm
Comparison of Peripapillary Retinal Nerve Fiber Layer (RNFL) Thickness between the Normal and Glaucoma Eyes with the Same Vertical Cup Disc Ratio (CDR) using Optical Coherence Tomography (OCT) Ni Gusti Ari Ayu Raiasih; Elvioza Elvioza; Virna Dwi Oktariana; Joedo Prihartono
Majalah Oftalmologi Indonesia Vol 41 No 3 (2015): Ophthalmologica Indonesiana
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/journal.v41i3.44

Abstract

Background: Glaucoma is a disease that belongs to a group of neurodegenerative diseases, such as impaired visual field and optic neuropathy with progressive damage to the optic nerve and retinal nerve fiber layer (RNFL) which is caused by the loss of ganglion cells and axon of the optic. Changes in the optic nerve and RNFL may occur prior to the abnormalities of the visual field nerves. Currently, the visual field examination should be performed to diagnose glaucoma but with patient-subjective result. Before it is detectable, visual field abnormalities are likely going to lose its ganglion cells by 40%. The purpose of this study was to assess and compare the peripapillary retinal nerve fiber layer (RNFL) between the normal and glaucoma eyes with vertical cup disc ratio (CDR) 0.4 to 0.7 in eye clinic Cipto Mangunkusumo Hospital (RSCM) Kirana. Methods: A total of 40 eyes of normal group and 34 eyes of glaucoma following Humphrey field analyzer examination and Optical Coherence Tomography (OCT) were evaluated. Peripapillary RNFL thickness between normal and glaucoma eyes were analyzed and compared each other. Eyes of glaucoma group then were grouped into early-stage glaucoma, according to the criteria in the initial stages of the examination results of Humphrey field analyzer. Result of peripapillary RNFL thickness was analyzed to get a cut off value. Results: Peripapillary RNFL thickness in the normal group with vertical CDR 0.4 to 0.7 was 111.3±9.8 μm to 118.0±3.0 μm, and glaucoma groups with vertical CDR 0.4 to 0.7 was 105.6±12.6 μm to 113.7±6.1 μm. Retinal nerve fiber layer thickness in normal group compared to glaucoma group in the superior quadrant, inferior, nasal, temporal and average on CDR 0.4 to 0.7 was not statistically significant (p>0.05), except on vertical CDR 0.6 average peripapillary RNFL (p<0.05). Cut off value of peripapillary RNFL in superior quadrant was 164 μm, inferior 169.5 μm, nasal 82.5 μm, temporal 73.5 μm and average 111.8 μm. Conclusion: There was no difference in changes of peripapillary RNFL along with the progression of vertical CDR but clinically, peripapillary RFNL thickness in glaucoma group is thinner than that of normal group with the same vertical CDR except in temporal quadrant. Keywords: Retinal nerve fiber layer (RNFL), cup disc ratio (CDR), optical coherence tomography (OCT)