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All Journal Jurnal Kesehatan JURNAL PENELITIAN PERAWAT PROFESIONAL
Clara Yulianti Tarigan
Universitas Lampung
Health Professions Medicine & Pharmacology Nursing Public Health Veterinary

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The Benefit of An Antioxidant on Atherosclerosis Clara Yulianti Tarigan
Jurnal Penelitian Perawat Profesional Vol 2 No 4 (2020): November 2020, Jurnal Penelitian Perawat Profesional
Publisher : Global Health Science Group

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/jppp.v2i4.209

Abstract

Atherosclerosis is a progresif change of artery walls which is marked by fat deposit, leukosit recrutiment and accumulation, foam cells formation, miosit migration and proliferation as well as extracellular matrix deposits which leads to thickening and hardening of artery.The aim of this literature review is to explain about. References which are used in this writing are 17 articles which are collected from PubMed NCBI and google scholar are all published in range of year 2005-2020. The keywords which are used for this literature searching area atherosclerosis, ROS, physical activities, stress oxidative, and antioxidant. The references which have been collected were analyzed by systematic literature review method which include collecting, evaluation, and development of research which certain focii. Atherosclerosis can occur due to excessive physical activities hence may cause the increase of ROS as a result of muscle cells aerobic metabolism process during physical activity. The rise in ROS may cause the inbalance between oxygen and antioxidant leading to stress oxidative. Antioxidant can be used to prevent the occurrence of stress oxidative. Antioxidant is a substance needed for the body to prevent free radicals and prevent the damage caused by it. Some of them are vitamin C and vitamin E as well as other herbal plants such as green tea and noni fruit.
The Benefit of An Antioxidant on Atherosclerosis Clara Yulianti Tarigan
Jurnal Penelitian Perawat Profesional Vol 2 No 4 (2020): November 2020, Jurnal Penelitian Perawat Profesional
Publisher : Global Health Science Group

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/jppp.v2i4.209

Abstract

Atherosclerosis is a progresif change of artery walls which is marked by fat deposit, leukosit recrutiment and accumulation, foam cells formation, miosit migration and proliferation as well as extracellular matrix deposits which leads to thickening and hardening of artery.The aim of this literature review is to explain about. References which are used in this writing are 17 articles which are collected from PubMed NCBI and google scholar are all published in range of year 2005-2020. The keywords which are used for this literature searching area atherosclerosis, ROS, physical activities, stress oxidative, and antioxidant. The references which have been collected were analyzed by systematic literature review method which include collecting, evaluation, and development of research which certain focii. Atherosclerosis can occur due to excessive physical activities hence may cause the increase of ROS as a result of muscle cells aerobic metabolism process during physical activity. The rise in ROS may cause the inbalance between oxygen and antioxidant leading to stress oxidative. Antioxidant can be used to prevent the occurrence of stress oxidative. Antioxidant is a substance needed for the body to prevent free radicals and prevent the damage caused by it. Some of them are vitamin C and vitamin E as well as other herbal plants such as green tea and noni fruit.
Efek Protektif Ekstrak Kulit Batang Bakau Rhizophora apiculata terhadap Kerusakan Histologi Paru Rattus norvegicus yang Diinduksi Asap Rokok Syazili Mustofa; Clara Yulianti Tarigan
Jurnal Kesehatan Vol 14, No 2 (2023): Jurnal Kesehatan
Publisher : Politeknik Kesehatan Tanjung Karang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26630/jk.v14i2.3752

Abstract

Rhizophora apiculata berpotensi dikembangkan sebagai antioksidan. Penelitian ini membandingkan efek protektif beberapa ekstrak kulit batang Rhizophora apiculata pada paru tikus yang terpapar asap rokok. Penelitian ini menggunakan 30 tikus yang dibagi menjadi 6 kelompok. Kelompok KN adalah kontrol normal yang tidak dipaparkan asap rokok. 5 kelompok lainnya mendapat paparan asap rokok 24 batang/hari selama 30 hari. K1 hanya dipaparkan asap rokok, kelompok K2 dipaparkan asap rokok dan diberikan vitamin C dengan dosis 9 mg/kgBB perhari. Kelompok lainnya dipaparkan asap rokok dan diberikan ekstrak etanol (P1) ekstrak methanol (P2) ekstrak n-heksana (P3) kulit batang Rhizophora apiculata. dengan dosis 56,55 mg/kgBB per hari selama 30 hari. Pada hari ke-31, tikus diterminasi dan dilakukan pemeriksaan mikroskopis paru untuk melihat kerusakan jaringan paru pada perbesaran perbesaran mikroskop 400x. Hasil rerata persentase kerusakan paru pada KN, K1, K2, P1, P2, dan P3 secara berurutan adalah 2; 40,667; 23,333; 20; 25,333; 24. Hasil skoring kerusakan paru pada KN, K1, K2, P1, P2, dan P3 secara berurutan adalah 0,06; 1,22; 0,70; 0,60; dan 0,76. Terdapat perbedaan bermakna (p-value
Co-Authors Syazili Mustofa