Nelvianti Nelvianti
Sekolah Tinggi Farmasi Indonesia Yayasan Perintis, Padang, Indonesia

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Pengaruh Ukuran Partikel Terhadap Solubilisasi Metronidazol dengan Menggunakan Brij 35 Febriyenti, Febriyenti; Halim, Auzal; Nelvianti, Nelvianti
Jurnal Farmasi Andalas Vol 1, No 1 (2013)
Publisher : Jurnal Farmasi Andalas

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Abstract

A Study has been done on the effect correlation effect of particle size on solubilization of metronidazol using brij 35 in water solvent. Surface tension method using Torsion Balance Type OS White. Inst. Co. Ltd and refraction method using Refractometer ABBE were done for determination of CMC (Critical Micelle Concentration) values of surfactans with Brij 35. Size of metronidazol particle was reduced by milling process with various duration 0 hour, 1 hour, 6 hours and 12 hours using Ball Mills “The Pascall Engineering”. Result showed that concentration of metronidazol in solubilization was 11,0888 mg/ml, 10,6470 mg/ml, 10,4431 mg/ml and 10,0890 mg/ml respectively at various milling period of 1 hour, 6 hour, 12 hour and without milling. Metronidazol after milling for 1 hour showed better solubilization than without milling with further. The Solubilization of metronidazol decreased with an increase in milling time. The Results at various time of milling process of 1 hour, 6 hours, 12 hours and without miliing. Process found the solubilization of metronidazol concentration were 11,0888 mg/ml, 10,6470 mg/ml, 10,4431 mg/ml and 10,0890 mg/ml. Keywords : Solubilization, Metronidazol, Brij 35, milling
KUALITAS PELAYANAN PENERBITAN AKTA KELAHIRAN PADA DINAS KEPENDUDUKAN DAN PENCATATAN SIPIL KOTA PALU Nelvianti, Nelvianti
Katalogis Vol 3, No 9 (2015)
Publisher : Katalogis

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Abstract

The purpose of this study was to find out how the quality of birth certificates issuance service at Palu City Population and Civil Registry. Types of data used were primary and secondary data. Data collection was done by means of observations, interviews, documentations. Informant determination technique was purposive sampling for the employees and accidental sampling for the community. Informants in this study were amounting to five (5) people. Analysis of data used was Miles and Huberman model, namely data reduction, data presentation, and conclusion. The theory used was the theory of Parasuraman in Tangkilisan. Birth certificate issuance service quality at the Office of Palu City Population and Civil Registry was still not good. It was known from the five aspects which were used as parameters in this study, namely direct evidence (tangibles): facility and infrastructure was inadequate and the employees appearance was not fully neat; reliability: the service provided was less precise and fast; responsiveness: the employees response was less fast enough to serve the needs or concerns of the community, assurance: there were still lacks of politeness and friendliness from the employees in serving the community; and empaty: there was a less fair service in serving the community.