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HUBUNGAN ANTARA KEPATUHAN PENGGUNAAN OBAT DAN KEBERHASILAN TERAPI PADA PASIEN HIPERTENSI DI RUMAH SAKIT DAERAH SURAKARTA TAHUN 2010 Mutmainah, Nurul
Pharmacon Vol 11, No 2 (2010)
Publisher : Pharmacon

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (152.434 KB)

Hipertensi merupakan penyakit kronis yang perlu diterapi dengan tepat dan terus menerus. Salah satu penentu keberhasilan terapi adalah adanya kepatuhan penggunaan obat oleh pasien. Adanya ketidakpatuhan berakibat tidak tercapainya tujuan terapi.Â Penelitian ini bertujuan mengetahui hubungan antara kepatuhan penggunaan obat dengan keberhasilan terapi pada pasien hipertensi di RS Daerah Kota Surakarta. Penelitian ini menggunakan jenis penelitian non eksperimental dengan rancangan analisis cross sectional dan pengambilan datanya menggunakan metode prospektif. Penelitian ini dilakukan pada 23 pasien hipertensi rawat jalan diÂ Â Rumah Sakit Daerah Surakarta, yang melakukan kontrol dan mendapat antihipertensi pada bulan September-Oktober tahun 2010 dimana sampel diambil dengan teknik purposiveÂ sampling. Hubungan skor kepatuhan dengan penurunan tekanan darah dianalisis menggunakan korelasi product moment. Ditemukan bahwa penyakit hipertensi lebih banyak diderita oleh perempuan dengan usia 47-60 tahun (52,2%). Penyakit lain yang juga diderita oleh pasien hipertensi terbanyak adalah diabetes mellitus (34,8%). Terapi antihipertensi yang banyak diberikan adalah dalam bentuk kombinasi 2 jenis obat yaitu Angiotensin Converting Enzym Inhibitor (ACEI) dan diuretik (34,8%).Â Sedangkan Â kepatuhan pasien ditemukan pada tingkat Â Â sedang (30,4%)Â Â dan tinggi ( 69,6%) dan dari analisis korelasi product moment ditemukan korelasi antara skor kepatuhan dengan penurunan tekanan darah sangat rendah, dimana Â Â tingkat kepatuhan mempengaruhi keberhasilan terapi sebesar 18,03%.Â Kata kunci: Hipertensi, Â kepatuhan, keberhasilan terapi

Evaluasi Penggunaan dan Efektivitas Antibiotik Profilaksis pada Pasien Bedah Sesar di Rumah Sakit Surakarta Tahun 2010 Mutmainah, Nurul; Setyati, Puri; Handasari, Niken
Indonesian Journal of Clinical Pharmacy Vol 3, No 2 (2014)
Publisher : Indonesian Journal of Clinical Pharmacy

Penggunaan antibiotik profilaksis pada operasi bedah sesar dapat mengurangi risiko infeksi yangberhubungan dengan komplikasi dan infeksi pascaoperasi. Penelitian ini bertujuan untuk mengetahuigambaran dan ketepatan penggunaan serta efektivitas antibiotik profilaksis pada pasien bedah sesar padadua rumah sakit di Surakarta tahun 2010. Penelitian ini termasuk penelitian deskriptif dengan pengambilandata rekam medis secara retrospektif. Analisis dilakukan terhadap penggunaan antibiotik yang meliputiketepatan antibiotik dibandingkan dengan ketepatan dosis danÂ waktu pemberian berdasarkan standar WHO. Sebanyak 200 pasien yang diteliti, ditemukan 76% berusia 20â35 tahun, usia kehamilan sudah cukup bulan (90,5%), lama perawatan di rumah sakit lebih dari 5 hari (46,5%), dan indikasi terbanyakbedah sesar adalah ketuban pecah dini (29%). Antibiotik profilaksis yang digunakan adalah ampisilin(24%), ampisilin-sulbaktam (23%), seftriakson (19,5%), sefotaksim (16%), amoksisilin-klavulanat(11%), danÂ sefazolin (6,5%). Ditemukan kesesuaian pemilihan obat dengan standar WHO (30,5%),yang meliputi tepat dosis (6,5%) dan tepat waktu pemberian (52%). Penggunaan antibiotik 100% efektifuntuk mencegah luka infeksi setelah operasi.Â Â Kata kunci: Antibiotik, bedah sesar, profilaksisEvaluation of the Use and Effectiveness of Antibiotics for Prophylactic inPatients with Cesarean SectionÂ at Hospitals in Surakarta in 2010AbstractThe use of antibiotics for prophylactic in sectio cesarean can reduce the risk of infection-relatedcomplications and postoperative infections. This study aims to describe and evaluate the usageÂ and theeffectiveness of prophylactic antibiotics in cesarean sectionÂ patients in two hospitals in Surakarta inyear 2010. The study used retrospective data from medical records. The analysis was then conducted onthe use of antibiotic including the appropriateness of antibiotic (compare to the standard of WHO), theappropriateness of dose and the time of administration. The data from two hundred of patientsÂ showedthat 76% of patients were between 20â35 years old and the patients with aterm pregnancy were 90.5%,46.5% of patients had the length of stay in hospital more than 5 days and 29% of cesarean deliveryindicated by amniotic premature rupture. Antibiotics that used for prophylactic were ampicillin (24%),ampicillin-sulbactam (23%), ceftriaxone (19.5%), cefotaxime (16%), amoxicillin-clavulanate (11%),and cefazolin (6.5%). It was found that 30,5% of drugs were selected based on standard,Â 6.5% of drugswere given in the appropriateÂ dose and 52% of drugs were administrated on-time. In conclusion, theantibiotics are 100% effective to prevent the incidence of surgical wound infection.Key words: Antibiotics, cesarean section, prophylactic

KAJIAN MEDICATION ERROR PADA KASUS STROKE DI RS X SURAKARTA TAHUN 2004 Mutmainah, Nurul
JFIOnline | Print ISSN 1412-1107 | e-ISSN 2355-696X Vol 4, No 1 (2008)
Publisher : Indonesian Research Gateway

Show Abstract | Download Original | Original Source | Check in Google Scholar

This work aimed to study the medication error occurred on stroke management at X Hospital in Surakarta during January-October 2004. Subject of the study were in-patient stayed at the hospital during January- July 2004 (retrospective study) and at September-October 2004 (prospective study). Result of the study showed that medication error had been occurred on 49 out 52 patient (94.23%) stayed at the hospital during January-July 2004 and on 16 out 18 (88.89%) patient stayed during September-October 2004. It was revealed that the types of medication error found in retrospective study were prescribing error (26.09%), wrong administration technique (68.12%) and monitoring error (5,9%). Non-rationale antibiotic use was 92.31% and unproper management of hyperglycemic in stroke patient was 45.45%. From prospective study it was revealed that the types of medication error found were prescribing error (25%) and wrong administration technique (75%). Non-rationale antibiotic use was 78.6%, unproper management of hyperglycemic in stroke patient was 12,5%, and medication side effect was 1,92%. ABSTRAK Penelitian ini bertujuan untuk mengkaji kejadian medication error pada terapi stroke di RS X Surakarta selama Januari-Oktober 2004. Subjek penelitian adalah pasien stroke yang menjalani rawat inap di RS X Surakarta periode Januari- Juli 2004 (studi retrospektif) dan periode September-Oktober 2004 (studi prospektif). Dari data yang diperoleh dilakukan kajian penggunaan obat dan outcome pasien yang memberi petunjuk telah terjadinya medication error. Pada studi retrospektif ditemukan adanya kejadian medication error dengan tipe prescribing error (26,09%), wrong administration technique (68,12%) dan monitoring error (5,9%). Penggunaan antibiotik yang kurang tepat ditemukan sebesar 92,31% dan penanganan hiperglikemi pada stroke yang kurang tepat sebesar 45,45%. Dari studi prospektif ditemukan kejadian medication error dengan tipe prescribing error (25%) dan wrong administration technique (75%). Penggunaan antibiotik yang kurang tepat sebesar 78,6%, penanganan hiperglikemi pada stroke yang kurang tepat sebesar 12,5%, dan kejadian efek samping obat sebesar 1,92%. Dari penelitian ini dapat disimpulkan bahwa dari 49 dari 52 (94,23%) pasien stroke pada bulan Januari-Juli 2004 dan 16 dari 18 (88,89%) pasien stroke pada bulan September-Oktober 2004 mengalami kejadian medication error.

The Evaluation of Antibiotics Using to Pediatric Acute Upper Respiratory Tract Infection Patients at Health Centers in Kunduran Blora 2013 Antoro, Tesar Zulmi; Mutmainah, Nurul
Pharmacon: Jurnal Farmasi Indonesia Vol 14, No 1 (2017)
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/pharmacon.v14i1.551

Acute respiratory tract infection is an acute infection which attacks one or more part of respiratory tractfrom nose to alveoli. This disease is an important society’s health problem especially in the developingcountries which attacks children easily especially who have low body’s immunity. This aim of the researchwas to know representation of the treatment and the accuracy of antibiotics distribution as the treatment ofpediatric patients of acute upper respiratory tract infection (AURTI) at Health Center in Kunduran, Blora2013 which is observed by appropriate parameter indication, appropriate drugs, appropriate dose andappropriate patients using the standard from WHO (2003). This research was categorized as qualitativeand non experimental research. In obtaining the data, the researcher trace the pediatric patient’s medicalrecord in the registration book in the health center Kunduran, Blora regency year 2013. The obtained datawas analyzed descriptively to evaluate the rationality of antibiotics distribution for AURTI. The researchresult showed that over 110 of the available samples in children aged up to 12 years old which werediagnosed as AURTI sufferer, 92 cases (83.63%) used amoxicillin antibiotics, 18 cases (16.37%) usedkotrimoksazol, 72 cases (65.50%) were proper indication, 59 case (53.63%) were proper drugs, 110 cases(100%) were proper patients, 87 case (79.09%) were proper dose, and 47 case (42.70) were rational in thetreatment

HUBUNGAN ANTARA KEPATUHAN PENGGUNAAN OBAT DAN KEBERHASILAN TERAPI PADA PASIEN HIPERTENSI DI RUMAH SAKIT DAERAH SURAKARTA TAHUN 2010 Mutmainah, Nurul
Pharmacon: Jurnal Farmasi Indonesia Vol 11, No 2 (2010)
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/pharmacon.v11i2.55

Hipertensi merupakan penyakit kronis yang perlu diterapi dengan tepat dan terus menerus. Salah satu penentu keberhasilan terapi adalah adanya kepatuhan penggunaan obat oleh pasien. Adanya ketidakpatuhan berakibat tidak tercapainya tujuan terapi. Penelitian ini bertujuan mengetahui hubungan antara kepatuhan penggunaan obat dengan keberhasilan terapi pada pasien hipertensi di RS Daerah Kota Surakarta. Penelitian ini menggunakan jenis penelitian non eksperimental dengan rancangan analisis cross sectional dan pengambilan datanya menggunakan metode prospektif. Penelitian ini dilakukan pada 23 pasien hipertensi rawat jalan di Rumah Sakit Daerah Surakarta, yang melakukan kontrol dan mendapat antihipertensi pada bulan September-Oktober tahun 2010 dimana sampel diambil dengan teknik purposive sampling. Hubungan skor kepatuhan dengan penurunan tekanan darah dianalisis menggunakan korelasi product moment. Ditemukan bahwa penyakit hipertensi lebih banyak diderita oleh perempuan dengan usia 47-60 tahun (52,2%). Penyakit lain yang juga diderita oleh pasien hipertensi terbanyak adalah diabetes mellitus (34,8%). Terapi antihipertensi yang banyak diberikan adalah dalam bentuk kombinasi 2 jenis obat yaitu Angiotensin Converting Enzym Inhibitor (ACEI) dan diuretik (34,8%). Sedangkan kepatuhan pasien ditemukan pada tingkat sedang (30,4%) dan tinggi ( 69,6%) dan dari analisis korelasi product moment ditemukan korelasi antara skor kepatuhan dengan penurunan tekanan darah sangat rendah, dimana tingkat kepatuhan mempengaruhi keberhasilan terapi sebesar 18,03%. Kata kunci: Hipertensi, kepatuhan, keberhasilan terapi

KAJIAN MEDICATION ERROR PADA KASUS STROKE DI RS X SURAKARTA TAHUN 2004 Mutmainah, Nurul
Jurnal Farmasi Indonesia Vol 4, No 1 (2008)
Publisher : Jurnal Farmasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35617/jfi.v4i1.8

This work aimed to study the medication error occurred on stroke management at X Hospital in Surakarta during January-October 2004. Subject of the study were in-patient stayed at the hospital during January- July 2004 (retrospective study) and at September-October 2004 (prospective study). Result of the study showed that medication error had been occurred on 49 out 52 patient (94.23%) stayed at the hospital during January-July 2004 and on 16 out 18 (88.89%) patient stayed during September-October 2004. It was revealed that the types of medication error found in retrospective study were prescribing error (26.09%), wrong administration technique (68.12%) and monitoring error (5,9%). Non-rationale antibiotic use was 92.31% and unproper management of hyperglycemic in stroke patient was 45.45%. From prospective study it was revealed that the types of medication error found were prescribing error (25%) and wrong administration technique (75%). Non-rationale antibiotic use was 78.6%, unproper management of hyperglycemic in stroke patient was 12,5%, and medication side effect was 1,92%. ABSTRAK Penelitian ini bertujuan untuk mengkaji kejadian medication error pada terapi stroke di RS X Surakarta selama Januari-Oktober 2004. Subjek penelitian adalah pasien stroke yang menjalani rawat inap di RS X Surakarta periode Januari- Juli 2004 (studi retrospektif) dan periode September-Oktober 2004 (studi prospektif). Dari data yang diperoleh dilakukan kajian penggunaan obat dan outcome pasien yang memberi petunjuk telah terjadinya medication error. Pada studi retrospektif ditemukan adanya kejadian medication error dengan tipe prescribing error (26,09%), wrong administration technique (68,12%) dan monitoring error (5,9%). Penggunaan antibiotik yang kurang tepat ditemukan sebesar 92,31% dan penanganan hiperglikemi pada stroke yang kurang tepat sebesar 45,45%. Dari studi prospektif ditemukan kejadian medication error dengan tipe prescribing error (25%) dan wrong administration technique (75%). Penggunaan antibiotik yang kurang tepat sebesar 78,6%, penanganan hiperglikemi pada stroke yang kurang tepat sebesar 12,5%, dan kejadian efek samping obat sebesar 1,92%. Dari penelitian ini dapat disimpulkan bahwa dari 49 dari 52 (94,23%) pasien stroke pada bulan Januari-Juli 2004 dan 16 dari 18Â (88,89%) pasien stroke pada bulan September-Oktober 2004 mengalami kejadian medication error.

Kepatuhan dan Kualitas Hidup Pasien Diabetes Melitus Tipe 2 di Rumah Sakit di Jawa Tengah Mutmainah, Nurul; Al Ayubi, Muhammad; Widagdo, Anggie
Pharmacon: Jurnal Farmasi Indonesia Vol 17, No 2 (2020)
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/pharmacon.v17i2.12281

Diabetes mellitus is a chronic disease that requires treatment for a long period of time. Adherence to consuming drugs is one of the most important things in achieving treatment goals. This study aims to determine the level of adherence and quality of life and determine the relationship to the quality of life of patients with type 2 DM in hospitals in Central Java. This study uses analytic design by asking cross-sectional. Samples were taken at two hospitals in Central Java. Sampling was purposive sampling with the criteria of type 2 diabetes mellitus patients who are undergoing outpatient care in the hospital, have undergone therapy for at least 3 months, and can communicate well. As a measurement used the Medication Adherence Rating Scale (MARS) questionnaire while the quality of life measure used the Short Form 36 (SF-36) questionnaire. Score data received and quality of life that has been obtained was processed with the SPSS (Product Statistics and Service Solutions) chi-square test. Research results in 200 respondents found 9 people (4.5%) had low adherence, 46 people (23%) were moderately related and 145 people (72.5%) have high adherence. While the quality of life found 41 people (20.5%) had a poor quality of life and 159 people (79.5%) had a good quality of life. The lowest aspect of quality of life is physical limitations and the highest aspect of quality of life is mental health. From the results of the analysis on the chi square test, the p value was obtained: 0.00. This shows that there is a significant relationship between adherence and quality of life in patients with Type 2 diabetes mellitus at the hospitals and a Prevalence Ratio value of 23.47.

Evaluasi Penggunaan dan Efektivitas Antibiotik Profilaksis pada Pasien Bedah Sesar di Rumah Sakit Surakarta Tahun 2010 Nurul Mutmainah; Puri Setyati; Niken Handasari
Indonesian Journal of Clinical Pharmacy Vol 3, No 2 (2014)
Publisher : Universitas Padjadjaran

Penggunaan antibiotik profilaksis pada operasi bedah sesar dapat mengurangi risiko infeksi yangberhubungan dengan komplikasi dan infeksi pascaoperasi. Penelitian ini bertujuan untuk mengetahuigambaran dan ketepatan penggunaan serta efektivitas antibiotik profilaksis pada pasien bedah sesar padadua rumah sakit di Surakarta tahun 2010. Penelitian ini termasuk penelitian deskriptif dengan pengambilandata rekam medis secara retrospektif. Analisis dilakukan terhadap penggunaan antibiotik yang meliputiketepatan antibiotik dibandingkan dengan ketepatan dosis dan waktu pemberian berdasarkan standar WHO. Sebanyak 200 pasien yang diteliti, ditemukan 76% berusia 20–35 tahun, usia kehamilan sudah cukup bulan (90,5%), lama perawatan di rumah sakit lebih dari 5 hari (46,5%), dan indikasi terbanyakbedah sesar adalah ketuban pecah dini (29%). Antibiotik profilaksis yang digunakan adalah ampisilin(24%), ampisilin-sulbaktam (23%), seftriakson (19,5%), sefotaksim (16%), amoksisilin-klavulanat(11%), dan sefazolin (6,5%). Ditemukan kesesuaian pemilihan obat dengan standar WHO (30,5%),yang meliputi tepat dosis (6,5%) dan tepat waktu pemberian (52%). Penggunaan antibiotik 100% efektifuntuk mencegah luka infeksi setelah operasi. Kata kunci: Antibiotik, bedah sesar, profilaksisEvaluation of the Use and Effectiveness of Antibiotics for Prophylactic inPatients with Cesarean Section at Hospitals in Surakarta in 2010AbstractThe use of antibiotics for prophylactic in sectio cesarean can reduce the risk of infection-relatedcomplications and postoperative infections. This study aims to describe and evaluate the usage and theeffectiveness of prophylactic antibiotics in cesarean section patients in two hospitals in Surakarta inyear 2010. The study used retrospective data from medical records. The analysis was then conducted onthe use of antibiotic including the appropriateness of antibiotic (compare to the standard of WHO), theappropriateness of dose and the time of administration. The data from two hundred of patients showedthat 76% of patients were between 20–35 years old and the patients with aterm pregnancy were 90.5%,46.5% of patients had the length of stay in hospital more than 5 days and 29% of cesarean deliveryindicated by amniotic premature rupture. Antibiotics that used for prophylactic were ampicillin (24%),ampicillin-sulbactam (23%), ceftriaxone (19.5%), cefotaxime (16%), amoxicillin-clavulanate (11%),and cefazolin (6.5%). It was found that 30,5% of drugs were selected based on standard, 6.5% of drugswere given in the appropriate dose and 52% of drugs were administrated on-time. In conclusion, theantibiotics are 100% effective to prevent the incidence of surgical wound infection.Key words: Antibiotics, cesarean section, prophylactic

Kepatuhan dan Kualitas Hidup Pasien Diabetes Melitus Tipe 2 di Rumah Sakit di Jawa Tengah Nurul Mutmainah; Muhammad Al Ayubi; Anggie Widagdo
Pharmacon: Jurnal Farmasi Indonesia Vol 17, No 2 (2020)
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/pharmacon.v17i2.12281

Diabetes mellitus is a chronic disease that requires treatment for a long period of time. Adherence to consuming drugs is one of the most important things in achieving treatment goals. This study aims to determine the level of adherence and quality of life and determine the relationship to the quality of life of patients with type 2 DM in hospitals in Central Java. This study uses analytic design by asking cross-sectional. Samples were taken at two hospitals in Central Java. Sampling was purposive sampling with the criteria of type 2 diabetes mellitus patients who are undergoing outpatient care in the hospital, have undergone therapy for at least 3 months, and can communicate well. As a measurement used the Medication Adherence Rating Scale (MARS) questionnaire while the quality of life measure used the Short Form 36 (SF-36) questionnaire. Score data received and quality of life that has been obtained was processed with the SPSS (Product Statistics and Service Solutions) chi-square test. Research results in 200 respondents found 9 people (4.5%) had low adherence, 46 people (23%) were moderately related and 145 people (72.5%) have high adherence. While the quality of life found 41 people (20.5%) had a poor quality of life and 159 people (79.5%) had a good quality of life. The lowest aspect of quality of life is physical limitations and the highest aspect of quality of life is mental health. From the results of the analysis on the chi square test, the p value was obtained: 0.00. This shows that there is a significant relationship between adherence and quality of life in patients with Type 2 diabetes mellitus at the hospitals and a Prevalence Ratio value of 23.47.

The Evaluation of Antibiotics Using to Pediatric Acute Upper Respiratory Tract Infection Patients at Health Centers in Kunduran Blora 2013 Tesar Zulmi Antoro; Nurul Mutmainah
Pharmacon: Jurnal Farmasi Indonesia Vol 14, No 1 (2017)
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/pharmacon.v14i1.551

Acute respiratory tract infection is an acute infection which attacks one or more part of respiratory tractfrom nose to alveoli. This disease is an important society’s health problem especially in the developingcountries which attacks children easily especially who have low body’s immunity. This aim of the researchwas to know representation of the treatment and the accuracy of antibiotics distribution as the treatment ofpediatric patients of acute upper respiratory tract infection (AURTI) at Health Center in Kunduran, Blora2013 which is observed by appropriate parameter indication, appropriate drugs, appropriate dose andappropriate patients using the standard from WHO (2003). This research was categorized as qualitativeand non experimental research. In obtaining the data, the researcher trace the pediatric patient’s medicalrecord in the registration book in the health center Kunduran, Blora regency year 2013. The obtained datawas analyzed descriptively to evaluate the rationality of antibiotics distribution for AURTI. The researchresult showed that over 110 of the available samples in children aged up to 12 years old which werediagnosed as AURTI sufferer, 92 cases (83.63%) used amoxicillin antibiotics, 18 cases (16.37%) usedkotrimoksazol, 72 cases (65.50%) were proper indication, 59 case (53.63%) were proper drugs, 110 cases(100%) were proper patients, 87 case (79.09%) were proper dose, and 47 case (42.70) were rational in thetreatment

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