Indrastuti Normahayu, Indrastuti
Department Of Radiology, Medical Faculty, University Of Brawijaya, RSUD Dr. Saiful Anwar

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Successful Therapy on Patients with Yolksac and Embrional Carcinoma by Surgery and Chemotherapy Prasetya, Fahmi Adhi; Djajalaksana, Susanthy; Retnani, Diah Prabawati; Isharanto, Artono; Normahayu, Indrastuti; Okta, Shinta
Malang Respiratory Journal Vol 2, No 01 (2020): Shape the Curves
Publisher : Universitaas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.mrj.2020.002.01.5

Abstract

Background: Malignant mixed germ cell tumors account for 13-25% of all non seminoma germ cell tumors, almost all cases were found in males (85%), increased in the third decade, and had an average survival rate of 40-45%. With modern management the average 5-year survival rate can be over 80%.Case Report: We reported a case report in Saiful Anwar Malang Hospital, Indonesia, a young man, 26 years old with an malignant epithelial tumor derived from mediastinal or lung. The CT scan of the chest showed an lobulated solid mass of iso-hipodens on the anterior superior mediastinum, mass encompassing the aortic arch, left pulmonalis artery, subclavian artery. The result from transthoracic FNAB with USG guidance showed an malignant epithelial tumor derived from mediastinal or lung, impression of an adeno squamous carcinoma. The AFP, LDH, and NSE serum level was elevated. Patient underwent a surgical sternotomy and tumor debulking. The biopsy showed an malignant mixed germ cell tumor (yolksac and embrional carcinoma). These were confirming the diagnosis of malignant mixed germ cell mediastinal tumor (yolksac and embrinonal carcinoma). Patient received a combination bleomycin, etoposid, cisplatin 3 series chemoteraphy  and evaluated.Conclusion: Some procedures like biopsy, tumor marker, could differentiate the subtype of mediastinal germ cell tumor. The multimodality treatment by combining surgical therapy (surgical sternotomy and tumor debulking) with chemotherapy could increase the survival rate of patients.
HIGH ALTITUDE PULMONARY EDEMA (HAPE) khiptiyah, mariyatul; Sartono, Teguh Rahayu; Normahayu, Indrastuti; Jaya, Wiwi
Malang Respiratory Journal Vol 3, No 1 (2021): Vol. 3 No. 1
Publisher : Universitaas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (343.796 KB) | DOI: 10.21776/ub.mrj.2021.003.01.3

Abstract

 Introduction: High altitude pulmonary edema (HAPE) is one of the acute, severe, non-cardiogenic disease that could be life threatening, occurs upon either the first or subsequent exposure to high altitude. It is triggered by a shortage of oxygen after ascending high altitude. The most effective therapeutic approach for HAPE is to immediately descend from high altitude and to give oxygenation, maintaining arterial saturation over 90%, as well as letting the patient rest from strenuous physical activity. The use of portable hyperbaric chamber is also deemed effective in certain circumstance, and nifedipine can also be used to treat HAPE, even as additional treatment in condition that the patients had yet to descend and oxygenation is still not administrable. Case Report: We reported a case at Rs. Dr. Saiful Anwar, a 23-year old male with High Altitude Pulmonary Edema (HAPE). Diagnosis established from anamnesis, physical examination, and laboratory tests. Patient complained shortness of breath when climbing Mt. Semeru, in which the patient reached an altitude of 2700 mdpl in 2 days. Physical examination showed oxygen saturation 46-49% with NRBM 10 lpm, and rhonchi breath sound in all lung areas. Laboratory examination showed leukocytosis, blood gas analysis showed hypocarbia, severe hipoxemia, metabolic acidosis, and type I respiratory failure. Ches XRay showed wide, irregular infiltrate in both lungs. Based on those, the patient was diagnosed with HAPE. In this case, the patient was given oxygenation.Conclussion: In this case, the patient was diagnosed with HAPE based on anamnesis, physical examination, and laboratory tests. Oxygenation given to the patient improved his condition.Key words: High altitude disease, Acclimatization, Pathophysiology, Management and treatment
DOSIS RADIASI DARI TINDAKAN CT-SCAN KEPALA Johan A. E Noor; Indrastuti Normahayu
Journal of Environmental Engineering and Sustainable Technology Vol 1, No 2 (2014)
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (272.334 KB) | DOI: 10.21776/ub.jeest.2014.001.02.3

Abstract

The research on mapping of mangrove distribution and spatial analysis of land suitability for pond aquaculture in coastal area of Gending sub District, Probolinggo are to map the distribution of existing mangrove forests along the coastal area of Gending and to determine the land suitability for aquaculture activities. This research used Landsat satellite imagery as an initial imaging data of the study area. Band manypulation using visual band 3-2-1, 4-3-2 and infrared bands 4-5-3. The use of this band based on their sensitivity in capturing the value of a high reflectance of vegetation. Rupa Bumi Indonesia Map scale 1: 25,000 from Bakorsurtanal used as a correction of satellite imagery. Furthermore, the survey field mapping with a model of participatory mapping done to calibrate the field data and sampling of water quality in the study area.Based on the analysis of satellite image and survey found that mangroves are spread almost evenly along the coastal area of Gending with a high density (visually) and identified along the coordinates of 762720 mT, 9144134 mU and 795851 mT, 9144081 mU. While the aquaculture area identified spread along the coastal with the coordinates 751394 mT, 9138874 mU to 776632 mT, 9147895 mU. Through the spatial analysis of land suitability described that most of the pond in the western part of coastal area is very suitable for aquaculture activities. Keywords: Mapping, mangroves, land suitability
ANORECTAL MALFORMATION WITH VAGINAL AGENESIS: A CASE REPORT Ginanda Nabilla Hardiyanti; Indrastuti Normahayu; Eggy Jita Pradana; Widanto
International Journal of Radiology and Imaging Vol. 2 No. 01 (2023): International Journal of Radiology and Imaging
Publisher : Department of Radiology, Medical Faculty, University of Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776//ub.ijri.2023.002.01.1

Abstract

Vaginal agenesis is characterised by primary amenorrhea in adolescent women and other abnormalities, such as the absence of the uterus. The incidence of vaginal agenesis or distal vaginal atresia associated with anorectal malformations is difficult to estimate. A 5-year-old patient, at birth, immediately cried, and faeces came out through an orifice in the skin under the vagina. Previously, the patient had planned for a posterior sagittal anorectoplasty (PSARP), but it was known that the patient did not have a vaginal opening at the time of surgery. The patient was diagnosed with a low-type anorectal malformation, vaginal agenesis, and a sigmoidostomy status. PSARP and vaginoplasty were performed while the patient was 7 years old. Clinical and radiographic examination in the first 3 days of age plays a role in determining the type of anorectal malformation and whether or not a colostomy is necessary. In children, MRI radiology plays a role in the preoperative examination to evaluate the size, morphology, and stage of development of the muscular sphincter. Keywords: anorectal malformations, vaginal agenesis.