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All Journal Indonesian Journal of Cancer
Ario Djatmiko
Department of Surgery, Onkologi Surabaya Hospital, Surabaya
Biochemistry, Genetics & Molecular Biology Immunology & microbiology Medicine & Pharmacology Public Health

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Quality of Life among Post-Mastectomy with and without Reconstruction Breast Cancer Patients in Onkologi Surabaya Hospital Cindy Angelina Limantara; Ario Djatmiko
Indonesian Journal of Cancer Vol 15, No 2 (2021): June
Publisher : National Cancer Center - Dharmais Cancer Hospital

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (245.295 KB) | DOI: 10.33371/ijoc.v15i2.766

Abstract

Background: The quality of life (QoL) of breast cancer (BCa) patients is an outcome of therapy that is often overlooked. In real life, postoperative breast cancer patients experience deep trauma in view that breasts are a symbol of femininity, which are very valuable for any female. This study aims to compare the QoL in patients who received mastectomy only and mastectomy with reconstruction.Methods: A retrospective comparative study of 25 post-mastectomy to 25 post-mastectomy with reconstruction BCa patients in Onkologi Surabaya Hospital. The subjects are patients who visited between July 2019 until March 2020, as many as 50 samples in accord with the inclusion and exclusion criteria. The assessment was performed using 3 instruments, including the hospital anxiety and depression scale (HADS), body image scale (BIS), and female sexual function index (FSFI). The collected data were analyzed using SPSS 15.0 for Windows.Results: A significant difference in mean values was seen in body image and sexual function. Post-mastectomy BCa patients presented more body image disturbance (p < 0.05). Better sexual function is claimed by post-mastectomy with reconstruction BCa patients in Onkologi Surabaya Hospital (p < 0.05). Meanwhile, the depression and anxiety values did not differ significantly in both groups (p > 0.05).Conclusions: Patients who underwent mastectomy and breast reconstruction have a better QoL in comparison with patients who received mastectomy only, in the domains of body image and sexuality function.
Embryo Cryopreservation as an Alternative to Treat Infertility in Breast Cancer Survivors in Reproductive Age: Case Reports Dwirani Rosmala Pratiwi; Noer Halimatus Syakdiyah; Ario Djatmiko; Lia Natalia Hinting
Indonesian Journal of Cancer Vol 16, No 4 (2022): December
Publisher : National Cancer Center - Dharmais Cancer Hospital

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33371/ijoc.v16i4.935

Abstract

Introduction: Chemotherapy has been shown to reduce breast cancer (BC) mortality significantly. However, several types of chemotherapy drugs affect the reproductive system. As BC has become increasingly prevalent, many young women are diagnosed during their reproductive years. As a result, overcoming chemotherapy-related infertility is becoming increasingly important. Hence, in-vitro fertilization (IVF) with embryo cryopreservation before chemotherapy is considered a way to preserve future reproductive potential. For this reason, this paper aims to report the cases of safe pregnancy in BC survivors through pre-chemotherapy IVF followed by embryo cryopreservation.Case Presentation: Two women, aged 35 and 29, respectively, were treated for BC by surgery, chemotherapy, and tamoxifen. They performed in-vitro fertilization (IVF) with embryo cryopreservation before chemotherapy. Their pregnancy was completed without complications, and they gave birth to healthy babies. Their last oncological visit also showed no signs of cancer recurrence, showing disease-free intervals of seven and eight years, respectively.Conclusions: Pre-chemotherapy IVF followed by embryo cryopreservation can be an alternative to treat infertility in BC survivors of reproductive age who are receiving chemotherapy.
Co-Authors Cindy Angelina Limantara Dwirani Rosmala Pratiwi Lia Natalia Hinting Noer Halimatus Syakdiyah