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Masfiyah Masfiyah
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Biochemistry, Genetics & Molecular Biology Chemistry Immunology & microbiology Medicine & Pharmacology Other

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PROFIL MIKROORGANISME PENYEBAB DERMATOFITOSIS DI RUMAH SAKIT ISLAM SULTAN AGUNG SEMARANG Hesti Wahyuningsih Karyadini; Rahayu Rahayu; Masfiyah Masfiyah
Media Farmasi Indonesia Vol. 13 No. 2 (2018): Media Farmasi Indonesia
Publisher : SEKOLAH TINGGI ILMU FARMASI YAYASAN PHARMASI SEMARANG

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Abstract

Fungal infections due to dermatophytes are often referred to as "Tinea". There are 3 genus which causes of dermatophytosis, among others are Trichophyton sp, Epidermophyton sp and Microsporum sp. The purpose of this study was to find out the profile of dermatophytosis-causing microorganisms in all patients in Sultan Agung Islamic Hospital Semarang. Samples are all patients with diagnosis of suspected dermatophytosis in Sultan Agung Islamic Hospital Semarang period January 2016 - December 2016. This research was descriptive research with Cross Sectional design. The sample was all patients with diagnosis of suspected dermatophytosis at Sultan Agung Islamic Hospital Semarang period January 2016 - December 2016. Research phase starting from pre analytic, analytic and post analytic stage. The results showed that the percentage of patients with dermatophytosis was more prevalent in female patients (53%) than in men (47%). Most dermatophytosis patients with tinea corporis diagnosis were 35% and tinea capitis was 29%, while for tinea pedis was 21%, tinea cruris was 12% and tinea unguium was 3%. The most dermatophyte fungi isolated are Microsporum canis 32%, Trichophyton mentagrophytes 18%, Microsporum audiounii 6%, Trichophyton rubrum 3%, Trichophyton tonsurans 3%. Microsporum canis is the most cause of dermatophytosis in Sultan Agung Islamic Hospital, Semarang.
PERBEDAAN ZONA HAMBAT CIPROFLOKSASIN DENGAN EKSTRAK KURMA (Phoenix dactylifera) TERHADAP BAKTERI GRAM NEGATIF SECARA IN VITRO Masfiyah Masfiyah; Rahayu Rahayu
Media Farmasi Indonesia Vol. 14 No. 2 (2019): Media Farmasi Indonesia
Publisher : SEKOLAH TINGGI ILMU FARMASI YAYASAN PHARMASI SEMARANG

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Date palm fruit (Phoenix dactylifera) is a fruit that has many benefits such as antioxidant,anti-bacterial, and anti-cancer effects. Dates also contain phytochemicals such aspolyphenols (flavonoids, isoflavones, lignin and phenolic acids), tannins, carotenoids, andsterols. This study aims to determine the activity of ciprofloxacin and dates (Phoenixdactylifera) against gram negative bacteria.This is an experimental laboratory research with a post-test only control groupdesign. Bacterial activity was assessed based on the diameter of the inhibition zone in MullerHinton agar with Kirby Bauer method. The gram-negative bacteria tested were Escherichiacoli and Klebsiella pneumoniae from clinical isolates that had been identified using VITEK®2. The concentration of the test bacteria was 0.5 Mac Farlan. The dates extract used wasAjwa dates extract ripe at 100% concentration using the socletation method with methanolsolvent. The test group was divided into 3 groups, namely the ciprofloxacin group only, theciprofloxacin group and the date palm extract, the date palm extract group only.There is no significant difference (P > 0.05) in the activity of ciprofloxacin andciprofloxacin with date palm extract against E. coli and Klebsiella pneumonia bacteria.There was no difference in the activity of ciprofloxacin or ciprofloxacin with theaddition of Ajwa date extract.
Co-Authors Hesti Wahyuningsih Karyadini Rahayu Rahayu