Novi Wijayanti Sukirto
Fakultas Kedokteran, Universitas Ahmad Dahlan, Yogyakarta

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Journal : Ahmad Dahlan Medical Journal

Risk Factors of Kidney Failure Patients in Sardjito Hospital Yogyakarta Dewi Yuniasih; Novi Wijayanti Sukirto; Barkah Djaka Purwanto
Ahmad Dahlan Medical Journal Vol. 1 No. 2 (2020): November 2020
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1118.708 KB) | DOI: 10.12928/admj.v1i2.3109

Abstract

The purpose of this study is to identify patients at high risk of kidney failure in order to plan treatment. Cross-sectional research method, carried out at the CAPD Outpatient Installation of Dr. Sardjito General Hospital, from October 2018 to November 2018. The results showed three major risk factors for kidney failure, namely hypertension (49.1%), diabetes (17.5%) %) and nephrotoxic (15.8%). The conclusion from the study is hypertension is the highest risk factor for kidney failure.
Risk Factor for Erythropoietin Resistance in Hemodialysis Patient : Literature Review Rachma Greta Perdana Putri; Amanatus Sholikhah; Novi Sukirto
Ahmad Dahlan Medical Journal Vol. 1 No. 2 (2020): November 2020
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1419.976 KB) | DOI: 10.12928/admj.v1i2.3131

Abstract

Anaemia become the complication of chronic kidney disease (CKD) which was caused by decreasing of erythropoietin. Erythropoietin stimulating agent (ESA) therapy is one of therapy to overcome the problem, but until 34% of patients have lack of response to ESA treatment. Anaemia in CKD related to the worsen of the diseases, quality of life, and mortality of patients. Decreasing of the response to erythropoietin need to be evaluated to correct anaemic condition. This review is aim to explain the risk factor for erythropoietin resistance. The literature for this review was collected through PUBMED and google scholar. Erythropoietin is glycoprotein secreted 90% by interstitial cells of kidney and 10% by liver cells. The functions of erythropoietin are stimulate the proliferation and cells differentiation in bone marrow, and enhance erythropoiesis. Renal damage can inhibit the secretion of erythropoietin. In patients with ESA treatment, risk factors for resistance are iron deficiency, inadequate haemodialysis, inflammation, hyperparathyroid, nutrition disturbance, antibody mediated Pure Red Cell Aplastic (PRCA). The risk factor can be influenced by genetic variation. Conclusion of this review, there are several factor that influence the response of erythropoietin in hemodialisa patients. Hence, study related anaemia in CKD need further study to optimalize the treatment.
Maternal characteristics and delivery method in patients with preeclampsia in PKU Muhammadiyah Bantul, Yogyakarta Irfan Rahmatullah; Rachma Greta Perdana Putri; Tiara Ismirahmadani; Novi Sukirto
Ahmad Dahlan Medical Journal Vol. 4 No. 1 (2023): May 2023
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Preeclampsia is the condition of pregnancy that has high mortality of mother and result some complication for the childbirth. The incidence of preeclampsia in the world reaches 10% whereas 3% -5% of them experience complications of eclamptic pregnancy. The objective of this study was to explore maternal characteristics and delivery methods of preeclampsia in order to predict the prognosis of the diseases and direct proper antenatal care. Methods: the study was Descriptive observational with a cross-sectional design at PKU Muhammadiyah Bantul during 2018-2020. Data were collected from medical records. The variables was compared using the Mann-whitney, kruskall wallis, and crosstabs as appropriate. Results: In this study, we found 77 women. Majority of patient’s age are less than 35 years old, 5 patients (6.50%) were mild preeclampsia and 52 patients (67.50%) were severe preeclampsia. Forty seven (61.04%) patients with preeclampsia were multigravida and 37 patients (48.05%) have normal BMI. Almost all patients without comorbid disease (96.10%) and history of preeclampsia (98.70%). Sixty eight patients (88.31%) have interpregnancy interval less than 5 years and without complication after delivery. Preeclampsia’s patients delivered at aterm gestational age (67.53%). Significantly, delivery method of the patients were cesarean section (74.03%; p = 0.01%).