Article Per Year (5 Year)
p-Index From 2019 - 2024
0.817
P-Index
This Author published in this journals
All Journal JURNAL FARMASIMED (JFM) Jurnal Pengmas Kestra (JPK)
Novidawati Boru Situmorang
staff
Health Professions Medicine & Pharmacology Nursing Public Health

Published : 4 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 4 Documents
Search

 1 
ANALGESIC ACTIVITY TEST OF WARU (Hibiscus tiliaceus L.) LEAVES ETHANOL EXTRACT IN MALE WHITE MISCULES (Mus musculus) Novidawati Boru Situmorang; Silvia Widya Ningsih
Jurnal FARMASIMED (JFM) Vol 5 No 1 (2022): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jfm.v5i1.1238

Abstract

Herbal remedies in therapy have been used in the treatment of pain since time immemorial. Pain is a sensory and emotional event that causes discomfort due to tissue damage. Most of the analgesics used in modern medicine have side effects on either the gastro-intestinal tract or the nervous system. Empirically waru leaves have been used as traditional medicine. The purpose of this study was to evaluate the analgesic effect of the ethanol extract of waru leaf and compare it with mefenamic acid tablets and then measured by the plantar test infra red (IR) 96 nm. Twenty five mice were divided into five groups. Three of them were treated with ethanol extract of waru leaves with doses of 100, 200, 300 mg/kgbw, 0.5% Na-CMC (negative control), and 500 mg Mefenamic Acid tablets (positive control). Infrared pain induction was performed every 10 minutes for 60 minutes. The maximum analgesic activity was indicated by a dose of 300 mg/kg body weight extract at 60 minutes which was 23.8 where the effectiveness was almost the same as the standard drug Mefenamic Acid, which was 24.3 while the dose of 200 mg/kgBB was 20.9 and 100 mg/kgBW was 19.9. The data obtained were then processed using one way ANOVA. The conclusion of the study revealed that hibiscus leaf (Hibiscus tiliaceus L.) has significant analgesic properties, especially in higher doses
UJI AKTIVITAS EKTRAK ETANOL DAUN SINTRONG (Crassocephalum crepidioides) TERHADAP BAKTERI Propionibacterium acnes Novidawati Boru Situmorang; Linia .
JURNAL PENGMAS KESTRA (JPK) Vol 1 No 2 (2021): Jurnal Pengmas Kestra (JPK)
Publisher : Lembaga Penelitian dan Pengabdian Kepada Masyarakat (LP2M) Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (404.467 KB) | DOI: 10.35451/jpk.v1i2.902

Abstract

Sintrong (Crassocephalum crepidioides) merupakan Salah satu tumbuhan yang berpotensi sebagai obat,Kandungan senyawa Flavonoid dalam daun Sintrong diyakini memiliki manfaat dan berpotensi sebagai antibakteriterhadap Propionibacterium acne. Selain itu adanya resistensi akan obat kimiawi mendorong peneliti untuk mencari alternatif pengobatan yang bersumber dari alam. Tujuan dari penelitian ini yaitu untuk mengetahui aktivitas antibakteri ekstrak etanol daun Sintrong (Crassocephalum crepidioides) terhadap bakteri propionibacterium acnes. Penelitian diawali dengan skrining fitokimia yaitu pemeriksaan senyawa golongan alkaloid, flavanoid, saponin, tanin dan selanjutnya dilakukan pengujian aktivitas antibakteri terhadap Propionibacterium acnes dengan metode difusi cakram. Larutan uji dibuat dengan konsentrasi yang berbeda yaitu ekstrak etanol daun sintrong 20%, 40%, 60% dan 80%, kontrol positif clindamycin 0,1%, kontrol negatif DMSO 0,1%. Hasil skrining fitokimia menunjukkan positif mengandung golongan alkoloid, flavonoid, tanin, saponin. Hasil pengujian aktivitas antibakteri menunjukkan bahwa ekstrak etanol daun sintrong memiliki aktvitas antibakteri terhadap Propionibacterium acne dengan diameter zona hambat sebesar 6,83 ± 0,27 (20%); 8,33 mm ± 0,36 (40%) dan 8,25 mm ± 0,31 (80%) yaitu zona hambat kategori sedang. Ekstrak etanol 60% menunjukkan zona hambat bakteri 10,05 mm ± 0,81 yaitu zona hambat kategori kuat. Clindamycin 0,1 % memiliki zona hambat bakteri 24,10 mm ± 0.61 yaitu zona hambat kategori sangat kuat. Dimetil sulfoksida 0,1% tidak memiliki daya hambat bakteri
EVALUATION OF THE USE OF AMLODIPIN IN HYPERTENSION PATIENTS IN THE HOSPITAL OF RSUD Drs. H. AMRI TAMBUNAN Novidawati Boru Situmorang; Yayuk Anjani
JURNAL PENGMAS KESTRA (JPK) Vol. 2 No. 1 (2022): Jurnal Pengmas Kestra (JPK)
Publisher : Lembaga Penelitian dan Pengabdian Kepada Masyarakat (LP2M) Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (609.443 KB) | DOI: 10.35451/jpk.v2i1.1125

Abstract

Hypertension is a chronic disease that often becomes a problem in health. One of the treatment patterns for hypertension patients that is often received by patients at the RSUD Drs. H. Amri Tambunan is Amlodipine from the CCB (Calcium Channel Blocker) group. The goal of hypertension treatment is to prevent morbidity and mortality due to high blood pressure by reducing pressure to as low as possible so as not to interfere with kidney function, brain function and quality of life. Hypertension is a disease that occurs due to an increase in systolic and diastolic blood pressure values ??of more than 130/80 mmHg on two measurements with an interval of five minutes in a calm state. Hypertension is a condition in which a person experiences an increase in blood pressure above normal, namely systolic blood pressure 140 mmHg or diastolic blood pressure 90 mmHg. Every 10 kg weight loss of obese patients can reduce 5-20 mmHg Systolic Blood Pressure (TDS). The purpose of this community service activity is so that people who seek treatment at Drs. H. Amri Tambunan can monitor his health condition. With the evaluation of the drug amlodipine, participants become more aware of matters related to hypertension and can take advantage of herbal plants that grow around their homes to prevent or treat hypertension.
TEST OF EFFECT KEDONDONG LEAF ETHANOL EXTRACT (SPONDIAS DULCIS) ON STAPHYLOCOCCUS AUREUS BACTERIA Novidawati Boru Situmorang; Nurdilla Fatima; Romauli Anna Teresia Marbun; Yanna Rotua Sihombing
Jurnal FARMASIMED (JFM) Vol 5 No 2 (2023): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jfm.v5i2.1541

Abstract

Bacteria that cause infection and disease are commonly found in our environment, one of which is Staphylococcus aureus bacteria. Several infectious diseases are also caused by Staphylococcus aureus, including cellulitis, acne (acne), and infection with Staphylococcal Scalded Skin Syndrome (SSSS). To determine whether the ethanol extract of kedondong leaves (EEDK) has antibacterial activity against Staphylococcus aureus bacteria. This study used a laboratory experimental method with several stages such as sample collection, identification of plants for making simplicia, phytochemical screening, extract preparation and preparation of kedondong leaf extract test solutions with various concentrations of 15%, 25%, 35% and positive control (Chloramphenicol), negative control (DMSO), and antibacterial activity testing using the paper disc method. The results of phytochemical screening of kedondong leaf simplicia (Spondias dulcis) found that kedondong leaves contain secondary metabolites such as alkaloids, flavonoids, tannins and saponins that have the potential to inhibit bacterial growth. % of 9.4 mm, 25% concentration of 13.5 mm and the greatest inhibition was at a concentration of 35% of 19.5 mm. Kedondong leaf extract has antibacterial activity against the growth of Staphylococcus aureus bacteria, with moderate to strong categories. inhibit the activity of Staphylococcus aureus bacteria is a concentration of 35%. Based on the description above, it was found that the EED with a concentration of 35% had the greatest antibacterial effect compared to the concentration of 15% and 25%. and it can be concluded that the higher the concentration of the extract used, the higher the antibacterial effect.
Co-Authors Linia . Nurdilla Fatima Romaulianna Theresia Marbun Silvia Widya Ningsih Yanna Rotua Sihombing Yayuk Anjani