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All Journal ISM (Intisari Sains Medis) : Jurnal Kedokteran
Yesicha Kurniawati
Intern of Pulmonology and Respiratory Medicine Department, Wangaya Regional General Hospital, Denpasar, Bali, Indonesia
Biochemistry, Genetics & Molecular Biology Medicine & Pharmacology

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Dramatic improvement in severe-critical COVID-19 patient after tocilizumab administration: a clinical experience Yesicha Kurniawati; Kadek Surya Atmaja; Ketut Suryana; Wayan Wahyu Semara Putra
Intisari Sains Medis Vol. 12 No. 1 (2021): (Available online : 1 April 2021)
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (321.573 KB) | DOI: 10.15562/ism.v12i1.951

Abstract

Background: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections in coronavirus disease 2019 (COVID-19) involve so many inflammatory cytokines, especially Interleukin-6 (IL-6). The usage of tocilizumab as an anti-IL-6 receptor antibody had been approved as COVID-19 medication.Case Presentation: This article reports a 51-year-old woman diagnosed with severe-critical COVID-19. The patient made significant progress after tocilizumab administration. The patient was hospitalized for 14 days before being discharged.Conclusion: Tocilizumab administration showed a significant improvement in COVID-19 patients.  However, further investigations are needed to explain this further.
Co-Authors Kadek Surya Atmaja Ketut Suryana Wayan Wahyu Semara Putra