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All Journal Jurnal Kedokteran Gigi Terpadu Jurnal Abdimas Kesehatan Terpadu
Moehamad Orliando Roeslan
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Biochemistry, Genetics & Molecular Biology Dentistry Education Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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Effect Of Ethanol, Hexane And Water Extracts Of Clinacanthus Nutans Leaves On Hone-1 Proliferation Moehamad Orliando Roeslan; Siti Ladia Fatima
Jurnal Kedokteran Gigi Terpadu Vol. 2 No. 1 (2020): Jurnal Kedokteran Gigi Terpadu
Publisher : Fakultas Kedokteran Gigi Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (555.141 KB) | DOI: 10.25105/jkgt.v2i1.7503

Abstract

Background: Mortality from cancer has increased especially in the developing country. Global pattern shows the half of mortality occurred in Asia. One type of cancer occurring in Indonesia is nasopharyngeal cancer. Clinacanthus nutans is a species of herbal plants in the Acanthaceae family that grows in tropical Asia, especially Indonesia. This plant is considered as one of traditional medicinal plants, which is effective in treating several diseases, including cancer. Different polarity of solvent that used to extract this plant will have different dissolved compounds. Objective: To determine the effect of ethanol, hexane, and water extract of C. nutans leaves on HONE-1 cell proliferation.Method: This study conducted using experimental research in vitro laboratory. Three different extract, ethanol, hexane, and water extract of C. nutans leaves treated to HONE-1 cell. Cell proliferation was measured using MTT assay.Result: The results showed significant differences (p <0.05) of treatments group compared to negative control. Ethanol extract showed the highest inhibition of HONE-1 cell proliferation.Conclusion: Ethanol, hexane, and water extract of C. nutans leaves could inhibit the HONE-1 cell proliferation
Pemberdayaan Ibu-Ibu Majlis Al Muttaqien dalam Budidaya Tanaman Dandang Gendis sebagai Larutan Kumur untuk Kesehatan Rongga Mulut Yenny Pragustine; Tri Erri Astoeti; Rahmi Amtha; Moehamad Orliando Roeslan
JURNAL ABDIMAS KESEHATAN TERPADU Vol. 1 No. 1 (2022): Jurnal Abdimas Kedokteran Terpadu
Publisher : Fakultas Kedokteran Gigi, Universitas Trisakti bekerjasama dengan Lembaga Penelitian dan Pengabdian kepada Masyarakat Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1174.373 KB) | DOI: 10.25105/jakt.v1i1.13921

Abstract

Dandang gendis is a herbal plant that is widely found in Asia. The plant has many benefits, in some South Asia country they used as antidote for snake venom or bug bites. In dentistry, the plant has been developed to help the healing process of the mucosa in the oral cavity. The background of this Community Service (PkM) activity is the lack of knowledge of housewives regarding the importance of maintaining their family’s oral health and herbal plants that can be used to maintain the health of the oral cavity. The purposes of this activity were to give information about oral health maintenance and introduce the utilization of dandang gendis leaves as a mouthwash solution for the family’s oral health, especially in the Ancol area. This PkM activity is expected to help housewives in maintaining the health of their family's oral cavity by using dandang gendis plants. The implementation was carried out offline on 26th March 2022 by giving lectures regarding the maintenance of oral health, introduction to dandang gendis and the use of dandang gendis leaves as a mouthwash solution, then the activity continued with discussion. The results showed that there is knowledge improvement based on the differences results of pre and post tests carried out.
Co-Authors Rahmi Amtha Siti Ladia Fatima Tri Erri Astoeti Yenny Pragustine