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All Journal Indonesian Journal of Cancer
Endang Yuli Purwani, Endang Yuli
Balai Besar Penelitian dan Pengembangan Pasca Panen Pertanian, Kementerian Pertanian, Jakarta
Health Professions

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Pati Resistan serta Perannya dalam Penghambatan Proliferasi dan Induksi Apoptosis Sel Kanker Kolon PURWANI, ENDANG YULI
Indonesian Journal of Cancer Vol 8, No 4 (2014): Oct - Dec 2014
Publisher : "Dharmais" Cancer Center Hospital

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Abstract

Resistant starch (RS) is starch fraction which is not digested by human starch degrading enzyme, and it will thus undergo bacterial fermentation in the colon. The main fermentation products are Short Chain Fatty Acid (SCFA): acetate, propionate and butyrate. The Fermentation products were able to inhibit the proliferation and to induce apoptosis of colon cancer cell. The apoptosis occured through mitochondrial pathway by changing the expression of pro-apoptosis related gene of Bax toward antiapoptosis related gene of Bcl-2.
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