Dadang Rukanta
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Hubungan Usia dan Lingkungan Pasien Tuberkulosis Paru Berdasarkan Hasil Positif dan Negatif Tes Cepat Molekular di RS Al-Islam Bandung Tahun 2018-2019 Nadya Safira; Yani Triyani; Dadang Rukanta
Bandung Conference Series: Medical Science Vol. 2 No. 1 (2022): Bandung Conference Series: Medical Science
Publisher : UNISBA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/bcsms.v2i1.167

Abstract

Abstract. The infectious disease with the highest mortality caused by the bacterium Mycobacterium tuberculosis is Tuberculosis (TB). There are several risk factors that can cause a person to get TB including the environment in which they live, age, and gender. The purpose of this study was to corelation the age and address of TB patients with positive and negative results of the rapid molecular diagnostics (RMD) at AL-Islam Hospital, Bandung. This research was conducted by analytical observation with a cross-sectional approach. The sampling technique used was purposive sampling from medical record data for 2018-2019 with the number of samples that entered the inclusion criteria as many as 253 people. Data analysis using Chi-square test. The results showed that there were 122 positive pulmonary TB patients (48.2%) and 131 negative patients (51.8%). Based on the positive age, the productive age was 99 people (39.1%) and based on the positive environment was the dense environment as many as 117 people (46.2%). The results of the bivariate statistical test showed that there was a relationship between productive age and the incidence of TB because many of these ages did things outside, but with the environment there was no relationship because apart from density there was another risk factor, namely humidity. Abstrak. Penyakit infeksi yang menular dengan kematian paling tinggi yang disebabkan bakteri Mycobacterium tuberculosis adalah penyakit Tuberkulosis (TB). Terdapat beberapa faktor risiko yang bisa menyebabkan seseorang terkena TB diantaranya adalah lingkungan tempat tinggal, usia, dan jenis kelamin. Tujuan penelitian ini adalah menghubungkan bagaimana usia, dan alamat pasien TB dengan hasil positif dan negatif Tes Cepat Molekular (TCM) di RS AL-Islam Bandung. Penelitian ini dilakukan secara observasional analitik dengan pendekatan cross-sectional. Teknik pengambilan sampel menggunakan Purposive Sampling dari data rekam medis tahun 2018-2019 dengan jumlah sampel yang masuk dalam kriteria inklusi sebanyak 253 orang. Analisis data menggunakan uji Chi-square. Hasil penelitian didapatkan bahwa pasien TB Paru yang positif 122 orang (48,2%) dan negatif 131 orang (51,8%). Berdasarkan usia yang lebih banyak yang positif adalah usia produktif sebanyak 99 orang (39,1%) dan berdasarkan lingkungan yang positif adalah lingkungan padat sebanyak 117 orang (46,2%). Hasil uji statistic bivariat menunjukkan terdapat hubungan antara usia produktif dengan kejadian TB dikarenakan banyak usia tersebut melakukan hal diluar, namun dengan lingkungan tidak terdapat hubungan dikarenakan selain kepadatan terdapat faktor risiko lain yaitu kelembapan.
Karakteristik Klinis dan Derajat Keparahan Pasien COVID-19 yang Menerima Azitromisin di RSUD Al-Ihsan Zacky Muttaqien; Heni Muflihah; Dadang Rukanta
Bandung Conference Series: Medical Science Vol. 2 No. 1 (2022): Bandung Conference Series: Medical Science
Publisher : UNISBA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/bcsms.v2i1.941

Abstract

Abstract. COVID-19 infect the respiratory tract, can be a predisposing factor for bacterial co-infection, which is can affect the severity to death. The antibiotics are given empirically, which is Azithromycin is often used for pneumonia indications. Azithromycin is macrolide antibiotic, effective against bacteria by inhibiting bacterial protein synthesis. Clinical characteristics and severity of COVID-19 can be an indication of taking Azithromycin. This research is aimed to describe the clinical characteristic and severity in the patients of COVID-19 taking Azithromycin. The research uses descriptive method with cross sectional approach. It uses the medical record of patients with confirmed COVID-19 hospitalized at the Al-Ihsan Hospital for the period August 2020 - March 2021. The sampling technique used was purposive sampling from medical record data with a total sample of 88 people who entered the inclusive criteria. The results of this research found that from the total of 88 subjects. Patients aged 18-60 years dominate 67 people (>75%) in Azithromycin groups. 46 people (52.27%) are severe COVID-19 (SpO2 ≤ 90%). Conclusion: The use of Azithromycin dominated age 18-60 years, had a comorbid condition and were used in patients with severe COVID-19 and non-severe COVID-19. Abstrak. Infeksi COVID-19 di saluran pernapasan dikatakan dapat menjadi faktor predisposisi dari ko-infeksi bakteri yang dapat berakibat buruk terhadap derajat keparahan hingga kematian. Pemberian antibiotik pada pasien COVID-19 secara empirik sering menggunakan obat dengan indikasi pneumonia seperti Azitromisin. Azitromisin adalah antibiotik golongan makrolida yang menghambat sintesis protein bakteri. Karakteristik klinis dan derajat penyakit dapat menjadi indikasi pemberian azitromisin. Tujuan penelitian ini adalah untuk mengetahui gambaran karakteristik klinis dan derajat keparahan pasien COVID-19 yang diberikan Azitromisin di RSUD Al-Ihsan, Bandung. Penelitian deskriptif ini menggunakan pendekatan cross sectional dan menggunakan data rekam medis pasien terkonfirmasi COVID-19 rawat inap di RSUD Al-Ihsan periode Agustus 2020 – Maret 2021. Sampel dilakukan dengan teknik purposive sampling. Total subjek penelitian 88 orang yang termasuk kriteria inklusi. Hasil penelitian menggambarkan pasien yang mendapatkan Azitromisin ini sebanyak 67 orang (76.13%) berusia 18-60 tahun dan 53 orang (48.76%) memiliki komorbid. Sebanyak 46 orang (52.27%) penerima Azitromisin memiliki COVID-19 derajat berat (SpO2 ≤ 90%). Kesimpulan: Pemberian Azitromisin didominasi karakteristik usia 18-60 tahun, dan memiliki komorbid. Terapi Azitromisin diberikan pada pasien dengan derajat COVID-19 tidak berat dan berat.