NICHOLAS TAMBUNAN, NICHOLAS
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Peran Faktor Nutrisi pada Pencegahan Kanker Prostat TAMBUNAN, NICHOLAS
Indonesian Journal of Cancer Vol 8, No 3 (2014): Jul - Sep 2014
Publisher : "Dharmais" Cancer Center Hospital

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (854.476 KB)

Abstract

Prostate cancer is a malignancy disease which originates in prostate organ that only can be found in men. This cancer is the second most common in men after lung cancer and the fifth in the entire world. The incidence will be increasing in the fifth decade of life with the peak in the eight decade. Several factors which are thought to be the etiology are: genetic, hormonal, diet, environment, and infection. Diet factor has great influence for both, the development and the prevention of this disease. Man who consumes high fat diet will have not only the risk to get that disease but also will increase the progresiveness of the disease. Several nutrients that are thought for decreasing the incidence of the prostate cancer are cruciferous vegetables and fruits which contain carotenoid. Furthermore, soya which contains much of isoflavon or phytoestrogen can also acts as the prevention of development of cancer cell. Green tea, lycopene ( carotenoid group that can be found in tomato products) can also act as the source of the antioxidant. This paper will discuss the role of nutrition factors of lycopene and soya in prostate cancer.
SUBURETERAL MUCOSA INJECTION WITH DETRANOMER/HYALURONIC ACID FOR VESICOURETERAL REFLUX TREATMENT: SYSTEMATIC REVIEW Tambunan, Nicholas; Rodjani, Arry; Wahyudi, Irfan
Indonesian Journal of Urology Vol 24 No 1 (2017)
Publisher : Indonesian Urological Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32421/juri.v24i1.271

Abstract

Objective: The aim of this study is to search the success rate of detranomer-hyaluronic acid (Dx/HA) used as injection through endoscopy approach and grades of vesicoureteral reflux (VUR) that could affect it success rate. Material & methods: We searched the literatures from MEDLINE database and PubMed from year 2001 until 2013. The data was analyzed using Random Effects Model with the method of Mantzel-Haenzel to analyze the success rates of dextranomer/hyaluronic acid and was determined by 95% Confidence of Interval (CI) disclosure. Meta-regression was performed to adjust the success rate compared with the grade of VUR as covariate. We assessed the heterogeneity by calculating the I2 statistic. All analyses were performed with Stata Statistical Software Version 12.0 (StataCorp). Results: We identified 9 literatures in full review. Of 1105 ureters that were injected with dextranomer/hyaluronic acid, 817 (72%; CI: 67-76%) were successfully treated according to author’s definition. The success rates of Dx/HA for pediatric with grade 1 VUR reached 80% (95% CI: 66-89%), whereas in grade 5 VUR only 50% (95% CI: 34-66%; p<0.05). Conclusion: The overall success rate of dextranomer/hyaluronic acid injection treatment was 72% after 3 months, although success rates varied widely among studies. Preoperative grade of VUR was significantly associated with treatment outcome. Increased VUR grade negatively affected success rates.