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All Journal Chemica: Jurnal Ilmiah Kimia dan Pendidikan Kimia Chemedu: Jurnal Ilmiah Pendidikan Kimia
Netti Herawati
Jurusan Kimia FMIPA UNM
Chemical Engineering, Chemistry & Bioengineering Chemistry Education Other

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Pengaruh Penambahan Sorbitol Pada Kitosan Terikat Silang Sebagai Bahan Plester Luka Sindy Parubak; Hasri Hasri; Netti Herawati
Chemica: Jurnal Ilmiah Kimia dan Pendidikan Kimia Vol 23, No 2 (2022): Chemica
Publisher : Jurusan Kimia FMIPA UNM

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (273.8 KB) | DOI: 10.35580/chemica.v23i2.35499

Abstract

ABSTRAKKitosan merupakan salah satu polimer yang cukup banyak diteliti sebagai plester luka sekaligus media penghantaran obat. Penelitian ini bertujuan untuk mengetahui karakteristik dan fleksibilitas plester luka dengan penambahan sorbitol pada kitosan. Pembuatan plester luka dilakukan dengan cara menambahkan larutan glutaraldehid 1% perbandingan 50 : 3 (v/v) kemudian ditambahkan sorbitol 2% dengan variasi volume  1–5mL yang dipanaskan pada suhu 60oC. Karakteristik plester luka melalui uji ketebalan, uji tarik, uji kapasitas retensi air, uji pelipatan dan laju transmisi uap air. Hasil karakterisasi plester luka yang diperoleh memiliki nilai ketebalan kisaran 0,2 – 0,3 mm, nilai uji tarik kisaran 1,4363 –  4,2445 MPa, nilai kapasitas retensi air kisaran 68,33 - 115%, uji pelipatan kisaran 298 - >300 kali, dan laju transmisi uap air kisaran 785,750– 858,000 g/m2. Berdasarkan hasil karakteristik dapat disimpulkan bahwa plester luka yang ideal ditunjukan penambahan sorbitol 3mL, 4mL dan 5 mL.Kata Kunci: Plester luka, kitosan, glutaraldehid, sorbitol. ABSTRACTChitosan is one of the polymers that is quite widely studied as a wound plaster as well as a drug delivery medium. This study aimed to find out characteristic and flexibility wound plasters with the addition of sorbitol in chitosan. Making wound plaster is carried out by adding a 1% glutaraldehyde solution in a ratio of 50: 3 (v / v) then adding 2% sorbitol with a volume variation of 1–5mL heated at a temperature of 60oC. Wound plaster characteristics through thickness test, tensile test, water retention capacity test, folding test and water vapor transmission rate. The result of the characterization of the wound plaster study have a thickness value of 0.2 – 0.3 mm, tensile test value range 1.4363 – 4.2445 MPa, water retention capacity value range 68.33 - 115%, test folding range 298 - >300 times, and water vapor transmission rate range 785,750 – 858,000 g / m2. Based on the results of the characteristics it can be concluded that the ideal wound plaster is indicated by the addition of 3 mL, 4 mL and 5 mL sorbitol.Keywords: Wound plaster, chitosan, glutardede, sorbitol.
Pengaruh Model Pembelajaran Inkuiri Terbimbing Terhadap Kemampuan Pemecahan Masalah Peserta Didik Kelas XI MIA di SMAN 11 Makassar (Studi Materi Pokok Laju Reaksi) Yulianti Palajukan; Sugiarti Sugiarti; Netti Herawati
ChemEdu Vol 2, No 2 (2021)
Publisher : Jurusan Kimia FMIPA UNM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35580/chemedu.v2i2.22404

Abstract

This study is a quasi-experimental research (Quasi Experiment) that aims to determine the effect of guided inquiry learning model to the problem-solving ability of students Class XI SMAN 11 Makassar. The study design used was "posttest-Only Control Group Design ".The study population was the students of class XI MIA SMA Negeri 11 Makassar consisting of six classes, while the sample is a class XI MIA 4 as an experimental class and class XI MIA 6 as the control class with the number of students each 34 people. The experimental class was studied by guided inquiry model. While the control class was with conventional learning models.The independent variable in this study was guided inquirí learning model and conventional learning model. The dependent variable is the ability to solving problem.Data retrieval problem solving skills performed by administering the test problem solving abilities. Problem-solving abilities data were analyzed using descriptive statistics and inferential statistics. The results of inferential statistical analysis of the data prerequisite troubleshooting capabilities indicate that the data on the class experimental and control classes were not normally distributed, but had a homogeneous variance. Hypothesis testing was done by using a non-parametric test of Mann-Whitney test with α = 0.05 was obtained Zcalculated> Ztable (2:02> 1.64). The effect of guided inquiry learning model to the problem-solving ability of students in class XI MIA SMAN 11 Makassar studies on the subject matter of the reaction rate.
Co-Authors Hasri Hasri Sindy Parubak Sugiarti Sugiarti Yulianti Palajukan