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All Journal The Indonesian Biomedical Journal Jurnal Pendidikan Kedokteran Indonesia: The Indonesian Journal of Medical Education
Dyah Samti Mayasari
Department Of Cardiology And Vascular Medicine, Faculty Of Medicine Public Health And Nursing, Universitas Gadjah Mada
Biochemistry, Genetics & Molecular Biology Health Professions Medicine & Pharmacology Public Health

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Increased Platelet-derived Microparticles Counts is Correlated with Elevated Blood LDL Cholesterol in Acute Myocardial Infarction Kelvin Supriami; Ira Puspitawati; Dyah Samti Mayasari; Anggoro Budi Hartopo
The Indonesian Biomedical Journal Vol 14, No 3 (2022)
Publisher : The Prodia Education and Research Institute (PERI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18585/inabj.v14i3.1892

Abstract

BACKGROUND: Platelet-derived microparticles (PDMPs) and low-density lipoprotein (LDL) cholesterol are contributing factors to acute myocardial infarction (AMI). However, the association between LDL cholesterol and PDMPs in AMI has not fully discovered. This study assessed the correlation between these two parameters in patients diagnosed with AMI.METHODS: This was an observational cross-sectional study involving 95 subjects with AMI. The blood measurement of PDMPs counts and LDL cholesterol levels were conducted concomitantly within 24 hours of admission. PDMPs count was analyzed by flow-cytometry method, meanwhile the LDL cholesterol was measured with enzymatic and colorimetric methods. For further analysis, subjects were further divided into LDL cholesterol level ≥130 mg/dL and <130 mg/dL. A statistical test was conducted for a correlative and comparative analyses.RESULTS: A correlative analysis to assess the association between PDMPs counts and LDL cholesterol level depicted a low but significant positive correlation (r=0.231, p=0.024). Furthermore, mean PDMPs counts was significantly higher in subjects with LDL cholesterol level ≥130 mg/dL compared to LDL cholesterol level <130 mg/dL (12,499.59 (95% CI: 8,507.44-16,491.74) counts/μL vs. 9,267.23 (95% CI: 4,445.45-14,089.01) counts/μL; p=0.039).CONCLUSION: There was a significant correlation between PDMPs counts and LDL cholesterol levels in AMI. A significantly increased PDMPs counts were found in subjects with LDL cholesterol level ≥130 mg/dL. Therefore, it is recommended to measure PDMPs in patients with high LDL cholesterol levels as both might be significant AMI biomarkers.KEYWORDS: acute myocardial infarction, LDL-cholesterol, platelet microparticles, platelet activation
AUGMENTED REALITY OF HEART IN TEACHING GROSS ANATOMY OF THE HEART: A LESSON LEARNED Hikmawati Nurrokhmanti,; Dyah Samti Mayasari; Nisrina Nabila; Annisa Maulidina; Putrika Gharini
Jurnal Pendidikan Kedokteran Indonesia: The Indonesian Journal of Medical Education Vol 11, No 4 (2022): Desember
Publisher : Asosiasi Institusi Pendidikan Kedokteran Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jpki.69741

Abstract

Background: Anatomy is a crucial science for medical students, the deep understanding on material would help students dealing with clinical context such give a better explanation to patients until having better performance in doing clinical procedure and dissecting ability as a surgeon. Nevertheless, having a deep understanding and memorizing anatomy would need abundant effort. Several strategies combined with fit learning media will give great advantages for the students. This study is aimed to explore innovation in teaching anatomy by using augmented reality (AR) within a case-based discussion.Methods:  A qualitative approach was used, in depth interview with teachers who facilitate the discussion and focus group discussion with the students. A thematic analysis was done in analyzing the data.Results: Overall, the teachers and student were satisfied with the innovation. Several themes were identified from students’ point of view such visualization, content, technical problem, and the need of teachers. The most important success factor of AR usage was its visualization i.e., orientation, and visual spatial ability.Conclusion: Combination case-based discussion with AR give promising strategies in understanding anatomy of heart. Using AR should consider several limitations of AR regarding to its visualization. Also considering the perceived advantages from the students, the usage of AR will be limited as supplement, a supporting media for having deep understanding on anatomy.
Co-Authors Anggoro Budi Hartopo Annisa Maulidina Hikmawati Nurrokhmanti, Ira Puspitawati Kelvin Supriami Nisrina Nabila Putrika Gharini