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Pemberian Ekstrak Etanol Biji Klabet (Trigonella foenum-graecum L.) Menurunkan Kualitas Spermatozoa Mencit (Mus musculus) Dewasa Muda Putu Susilawati; Bagus Komang Satriyasa; I Gusti Ayu Widianti
Metamorfosa: Journal of Biological Sciences Vol 9 No 2 (2022)
Publisher : Prodi Magister Ilmu Biologi, Fakultas MIPA, Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/metamorfosa.2022.v09.i02.p11

Abstract

This study aimed to determine the activity of the ethanol extract of Fenugreek Seed (Trigonella foenum-graecum Linn.) to reduce the sperm quality of young adult mice (Mus musculus) as a natural male contraceptive. This research is an experimental study using a post-test only control group design. The sample of this study consisted of 36 male Swiss Webster (Mus musculus) mice aged 2-3 months with a body weight of 20-30 grams which were divided into two groups randomly. The control group (P0) was given 0.5 ml of CMC Na 0.3% and the treatment group (P1) was given the ethanol extract of Fenugreek Seed (Trigonella foenum-graecum Linn.) 0.4 mg/gram BW as much as 0.5 ml for 36 day orally. The results showed that the administration of ethanol extract of Fenugreek Seed (Trigonella foenum-graecum Linn.) could reduce the quality (concentration, motility, viability, and morphology) of spermatozoa (P?0.05), so that Fenugreek Seed (Trigonella foenum-graecum Linn.) has potential as a natural male contraceptive.