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All Journal Jurnal Kedokteran Diponegoro
Muflihatul Muniroh
Department of Physiology, Faculty of Medicine, Diponegoro University, Semarang
Medicine & Pharmacology

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Relationship of Sleep Quality with Short-Term Memory and Reaction Time in First Year Medical Students of Diponegoro University Rizki Gatot Febrian; Santoso Jaeri; Muflihatul Muniroh; Darmawati Ayu Indraswari
JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL) Vol 10, No 5 (2021): JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL)
Publisher : Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/dmj.v10i5.31391

Abstract

Abstract Background: Sleep disturbance is a disorder that includes a lack of quantity and quality of sleep. Students, especially medical students, have a high risk of getting sleep disorders of poor sleep quality and quantity. Poor sleep quality can interfere with memory. Besides, poor sleep quality also results in fatigue, which can lead to increased reaction time.Aim: To determine the relationship between sleep quality and short-term memory and reaction time in first-year medical students of Diponegoro University.Methods: This Observational study used a cross-sectional design with first-year medical students of Diponegoro University as the subjects. Kolmogorov-Smirnov was applied as the normality test, then the hypothesis test between sleep quality and short-term memory used the Pearson Chi-Square test, while sleep quality and reaction time used the Mann-Whitney U test. Results: Two hundred students participated in the study. Eighty two people (41%) had good sleep quality, 118 people (59%) had poor sleep quality. The p value of the relationship between sleep quality and short-term memory showed insignificant result (p=0.791). Meanwhile, the Mann-Whitney test to measure the relationship between sleep quality and reaction time was also insignificant (p=0.270).Conclusion: There is no significant relationship between sleep quality with reaction time and short-term memory in first-year medical students of Diponegoro University.
ANTIHYPERURICEMIC EFFECT OF RED GINGER POWDER AND LIME JUICE COMBINATION IN WISTAR RATS INDUCED HYPERURICEMIA Eva Susanty Purba; Chikita Dian Rahma Saphira; Salma Yasmine Azzahara; Edwin Basyar; Muflihatul Muniroh; Ainun Rahmasari Gumay
JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL) Vol 10, No 1 (2021): JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL)
Publisher : Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/dmj.v10i1.29374

Abstract

Background: Hyperuricemia is an abnormally high level of uric acid in the blood. Ginger and lime are natural ingredients that contain antioxidants and anti-inflammatory which could reduce blood uric acid levels. This study aims to prove the effect of red ginger powder and lime juice combination on uric acid levels of Wistar rats induced hyperuricemia.Methods: Experimental research with pre and post-test only control group design. Thirty Wistar male rats, aged 2-3 months, weighed 150-350 grams randomly divided into 5 groups. Group C1 was normal control group. Group C2 was induced by single intraperitoneal injection of potassium oxonate (300mg/kgBW). Group T1, T2, T3 were induced by potassium oxonate and orally administered by combination of red ginger powder (300, 600, 1200 mg/200gBW) and lime juice (2ml/150gBW). Blood samples in each group will be collected in 1 hour after treatment. Uric acid levels were measured using the TBHBA uric acid method.Results: Uric acid level in T1, T2, and T3 group was significantly lower than C2 group (p<0,05). The most effective dose to reduce uric acid levels was 1200mg/200gBW red ginger in combination with 2ml/150gBW lime juice (T3 group).Conclusion: Red ginger powder and lime juice may reduce the blood uric acid levels in Wistar rats induced hyperuricemia.
Co-Authors Ainun Rahmasari Gumay, Ainun Rahmasari Chikita Dian Rahma Saphira Darmawati Ayu Indraswari Edwin Basyar Eva Susanty Purba Rizki Gatot Febrian Salma Yasmine Azzahara Santoso Jaeri