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Fransiska Rismauli Natallya
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Immunology & microbiology Public Health

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Retrospective Study of Skin Prick Test in Atopic Dermatitis Patients at DermatoVenereology Outpatient Clinic of Dr. Soetomo General Hospital Surabaya During 2007-2012 Natallya, Fransiska Rismauli; Barakbah, Jusuf
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol 27, No 1 (2015): BIKKK APRIL 2015
Publisher : Faculty Of Medicine Airlangga University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (124.433 KB) | DOI: 10.20473/bikkk.V27.1.2015.9-16

Abstract

Background: Atopic dermatitis (AD) gives impact on quality of life of patients because of  frequent exacerbation. Various factors play a role in pathogenesis of AD. Trigger factors of exacerbation especially due to enviroment including irritant and allergen agents. Identifying and avoiding trigger factors are important in management of AD. Skin prick test (SPT) is one method to detect the presence of Ig E spesific to certain allergens (food allergens, aeroallergens). Purpose: To describe the characteristic of AD patients, and evaluate the result of SPT and their clinical relevance. Methods: This research was a retrospective study of AD patients who underwent SPT  during 2007-2012. Results: Nineteen of 57 patients (33,3%) had positive SPT to one or more allergens, and 36 patients (63,1%) had negative result. One patient (1,8%) showed false positive result and 1 patient (1,8%) showed false negative result. The most common allergens were house dust in 8 patients (42%) and crab in 6 patients (31,6%). Clinical relevance was found in 11 patients (58%), and 8 patients (42%) had no clinical relevance. Compared with SPT–negative patients, SPT–positive patients showed more severe symptom and clinical manifestation. Conclusions: In this study, the allergens could be detected in 19 patients (33,3%) by SPT, mostly to house dust (42%) and crab (21,6%). Clinical relevance was found in 11 patients (58%). SPT is recomended to perform in management of AD in order to detect enviromental allergen because it has significant clinical relevance. Key words: atopic dermatitis, skin prick test, allergens.
Retrospective Study of Skin Prick Test in Atopic Dermatitis Patients at DermatoVenereology Outpatient Clinic of Dr. Soetomo General Hospital Surabaya During 2007-2012 Fransiska Rismauli Natallya; Jusuf Barakbah
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 27 No. 1 (2015): BIKKK APRIL 2015
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (124.433 KB) | DOI: 10.20473/bikk.V27.1.2015.9-16

Abstract

Background: Atopic dermatitis (AD) gives impact on quality of life of patients because of  frequent exacerbation. Various factors play a role in pathogenesis of AD. Trigger factors of exacerbation especially due to enviroment including irritant and allergen agents. Identifying and avoiding trigger factors are important in management of AD. Skin prick test (SPT) is one method to detect the presence of Ig E spesific to certain allergens (food allergens, aeroallergens). Purpose: To describe the characteristic of AD patients, and evaluate the result of SPT and their clinical relevance. Methods: This research was a retrospective study of AD patients who underwent SPT  during 2007-2012. Results: Nineteen of 57 patients (33,3%) had positive SPT to one or more allergens, and 36 patients (63,1%) had negative result. One patient (1,8%) showed false positive result and 1 patient (1,8%) showed false negative result. The most common allergens were house dust in 8 patients (42%) and crab in 6 patients (31,6%). Clinical relevance was found in 11 patients (58%), and 8 patients (42%) had no clinical relevance. Compared with SPT–negative patients, SPT–positive patients showed more severe symptom and clinical manifestation. Conclusions: In this study, the allergens could be detected in 19 patients (33,3%) by SPT, mostly to house dust (42%) and crab (21,6%). Clinical relevance was found in 11 patients (58%). SPT is recomended to perform in management of AD in order to detect enviromental allergen because it has significant clinical relevance. Key words: atopic dermatitis, skin prick test, allergens.
Allergic Contact Dermatitis due to Henna Tattoo with Secondary Infection Fransiska Rismauli Natallya; Marsudi Hutomo
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 28 No. 1 (2016): APRIL
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (170.608 KB) | DOI: 10.20473/bikk.V28.1.2016.65-70

Abstract

Background: Recently henna tattoo become popular. Incidence of allergic contact dermatitis due to henna tattoo is increasing. Para-phenylenediamine (PPD) is suspected as a contact sensitizer because it is often added to henna tattoo to make a darker color. Patch test is needed to determine the allergen. Case: A 18 year-old woman with chief complaint itchy redness patches, burning sensation, and blisters containing pus on her lower left arm after she applied henna tattoo on those site 3 days before. It was the second time applying henna and the reaction was appeared. The patient was treated with oral antibiotic for 5 days, oral antihistamine, and wet dressing with NaCL 0.9% for 3 days. Three days after wet dressing, topical corticosteroid was applied, and the lesion resolved. Patch test was performed 10 months later and showed positive reaction to PPD and toluenesulfonamide formaldehyde resin (TSFR). The previous history, patient had allergy to nail polish which TSFR was suspected as a contact sensitizer. Discussion: Allergic contact dermatitis is a hypersensitivity reaction caused by skin contact with an environmental allergen. Prior sensitization is required for allergy to develop. Patch test is the gold standard to determine the allergen. Based on history and physical examination, clinical relevance of patch test showed positive current relevance (possible) for PPD, and past relevance for TSFR. Conclusion: Avoiding the allergens are important in the management of contact dermatitis.Key words: Allergic contact dermatitis, henna tattoo, para-phenylenediamine (PPD), patch test.
Co-Authors Jusuf Barakbah, Jusuf Marsudi Hutomo