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All Journal Berkala Ilmu Kesehatan Kulit dan Kelamin
Anggraeni Noviandini, Anggraeni
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Immunology & microbiology Public Health

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Profil Uji Tempel pada Pasien Dermatitis Kontak Noviandini, Anggraeni; Prakoeswa, Cita Rosita Sigit
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol 26, No 2 (2014): BIKKK AGUSTUS 2014
Publisher : Faculty Of Medicine Airlangga University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (114.788 KB) | DOI: 10.20473/bikkk.V26.2.2014.1-7

Abstract

Latar belakang: Prevalensi Dermatitis Kontak (DK) di Unit Rawat Jalan (URJ) Kesehatan Kulit dan Kelamin RSUD Dr. Soetomo Surabaya semakin meningkat dalam 10 tahun terakhir. Identifikasi penyebab dengan uji tempel penting untuk memberikan penatalaksanaan yang tepat pada pasien tersebut. Sampai saat ini penelitian mengenai prevalensi dan insidensi DK di Indonesia masih terbatas. Tujuan: Menentukan prevalensi dan interpretasi hasil uji tempel positif terhadap alergen yang dicurigai. Metode: Penelitian retrospektif tentang uji tempel menggunakan The European Baseline Series of Contact Allergens yang telah dilakukan terhadap 42 pasien. Interpretasinya dicatat dan dievaluasi berdasarkan pemeriksaan klinis pasien. Hasil: Dari 42 pasien yang dilakukan uji tempel, 27 pasien (64,3%) menunjukkan hasil positif dengan satu atau lebih alergen tes. Alergen terbanyak adalah p-phenylenediamine (40,5%), fragrance mix I (16,7%), formaldehyde (14,3%). Dermatitis wajah dilaporkan pada 81,5% pasien, 97,6% terdiagnosis Dermatitis Kontak Alergika (DKA). Prevalensi tertinggi pada wanita, usia muda, dan mayoritas pelajar. Simpulan: Profil DK di URJ Kesehatan Kulit dan Kelamin RSUD Dr. Soetomo Surabaya berbeda dengan daerah lain di Indonesia, karena perbedaan pola hidup menyebabkan paparan lingkungan terhadap alergen berbeda pada tiap area. Katakunci: uji tempel, dermatitis kontak, retrospektif.
Patch Test and Repeated Open Application Test (ROAT) in Allergic Contact Dermatitis Noviandini, Anggraeni; Prakoeswa, Cita Rosita Sigit
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol 26, No 3 (2014): BIKKK DESEMBER 2014
Publisher : Faculty Of Medicine Airlangga University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (819.13 KB) | DOI: 10.20473/bikkk.V26.3.2014.1-9

Abstract

Background: The clinical relevance of patch test reaction is often difficult to determine. Repeated Open Application Test (ROAT) have been developed to further evaluate the significance of patch test result. Purpose: Understanding methods, procedures, and reactivity of patch test and ROAT, so thatmay be used to help identify with a high risk of developing allergic contact dermatitis. Reviews: The validity of patch test is limited. Various attempts have been made at modifying the patch test, primarily in order to increase the sensitivity of the skin and thus enhance the reliability and validity of the results, such as ROAT. Several experimental studies have compare the result of patch testing with the outcome of ROATs and these have defined correlations between the threshold concentration at patch testing (MEC) and outcome of ROAT, and also shed light on some factors that may influence the outcome of ROATs. Results of patch testing with serial dilutions of colophony, cinnamic aldehyde, and isoeugenol have shown concordance with the outcome of ROATs. On the other hand, poor correlation between patch test reactivity and ROAT were demonstrated in another study on isoeugenol,hydoxycitronellal, formaldehyde dan chromium. Conclusion: Patch test and ROAT are two methods that may be used toidentify allergen exposure and MEC Allergic Contact Dermatitis reaction.Key words: patch test, repeated open application test (ROAT), allergic contact dermatitis (ACD).
Co-Authors Cita Rosita Sigit Prakoeswa