Article Per Year (5 Year)
p-Index From 2019 - 2024
0.983
P-Index
This Author published in this journals
All Journal Qanun Medika - Medical Journal Faculty of Medicine Muhammadiyah Surabaya Medical and Health Science Journal Oceana Biomedicina Journal Hang Tuah Medical Journal
RISMA
Fakultas Kedokteran Universitas Hang Tuah
Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Medicine & Pharmacology Nursing Public Health Social Sciences

Published : 5 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 5 Documents
Search

 1 
PENGARUH EKSTRAK DAUN PEPAYA (Carica papaya) TERHADAP KEMATIAN LARVA NYAMUK Aedes agypti INSTAR III Jonathan Payangka; Risma Risma; Prajogo Wibowo
Jurnal Ilmu Kesehatan dan Kesehatan Vol 3 No 1 (2019): FEBRUARY
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/mhsj.v3i1.921

Abstract

Background: Papaya leaves (Carica papaya) extract is a natural larvacide that contains papain and alkaloid karpain so its usage is safe for the environment. The larvacide properties can also be used to reduce the amount of Aedes aegypti mosquito larvae. This mosquito species is the main vector for the virus that causes dengue fever which incident number increases over the years. There have been a few methods used to control the mosquito’s amount, one of which is by decreasing the number of Aedes aegypti’s larvae using the organophosphate insecticide chemical known as temefos. Temefos is really effective in killing the Aedes aegypti larvae but it has a lot of side effects especially towards the environment. By controlling the number of the Aedes aegypti’s larvae, hopefully the number of the dengue fever case can also be reduced. Objective: To prove that the papaya leaves (Carica papaya) extract have effects on the death of Aedes aegypti’s instar III larvae. Method: This is an experimental research what uses a post test only control group design. The study consists of seven groups, which are positive control that is given abate powder, negative control that is given only aquadest, and five groups treated with concentrations of 0.5%, 1%, 1.5%, 2%, and 2.5%; repeated for four times. The calculation of the amount of dead larvae is done within the first 24 hours. Result: Based on the Kruskal-Wallis test, p’s value is <α with p value being 0.000 and α being 0.05. It proves the significance of the experiment. Conclusion: The papaya leaves (Carica papaya) extract have effects on the death of Aedes aegypti’s instar III larvae
The Effect of Thespesia populnea Against Plasmodium falciparum Enoyl Acyl Carrier Protein Reductase Receptor by Study In Silico I Made Prasetya Kurniawan; Prawesty Diah Utami; Risma Risma
Qanun Medika - Jurnal Kedokteran FK UMSurabaya Vol 5, No 2 (2021)
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jqm.v5i2.5368

Abstract

Indonesia is a country that has abundant natural resources; one of them is the Baru laut plant which is the latest breakthrough because it has an active substance that can be used as an anti-malaria medicine. It is very beneficial because there has been a case of resistance of artemisinin derivatives in Indonesia. The purpose of this study was to determine the potential of active compounds in Baru laut plants (Thespesia populnea (L.) Soland ex. Correa) against the Plasmodium falciparum enoyl acyl carrier protein reductase receptor in P. falciparum through in silico studies. This research is purely experimental using the One-Shot Experimental Study research design method. Observations were only made once between the variables studied through three analyzes, namely prediction analysis of active compound content, prediction analysis of the mechanism of action of active compound content, and prediction analysis of ADME active compound. The study results show that there are three active compounds in Baru laut plants that have antimalarial potential. The three compounds include gossypol, linoleic acid, and beta-sitosterol, have their respective potential in becoming a malaria drug. This study concludes that Baru laut plants have potential as anti-malaria drugs.
Prevalence of Trichomoniasis in Cervical Cancer Patients Luh Putu Diah Ayuning; Risma Risma; Prawesty Diah Utami
Jurnal Ilmu Kesehatan dan Kesehatan Vol 6 No 1 (2022): FEBRUARY
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/mhsj.v6i1.2543

Abstract

Backgroud: Trichomoniasis is the most frequent non-viral sexually transmitted disease in the world, and it can lead to persistent HPV infection. Trichomonas vaginalis infection causes damage to the vaginal mucosa, activation of oncogenes and inactivation of tumor suppressor proteins, and production of non-specific oxidants that lead to cervical cancer. This study aims to determine the prevalence of trichomoniasis in cervical cancer patients. Methods: This study uses systematic literature review method and uses 10 international journals obtained through machine learning and indexed in Scimago.  Journals are screened through PRISMA and have gone through a critical appraisal process.This study took place from April to September 2021.  Results: The prevalence of trichomoniasis in cervical cancer patients ranged from 0.022% to 87.7%, according to the findings of this study. The prevalence results vary due to differences in demographics and diagnostic methods used. Statistical analysis of the association between trichomoniasis and cervical cancer varied between significant and insignificant. Differences in the association are influenced by the research design used, diagnostic methods, and sample of the research. Conclusions: The conclusion of this study is that the prevalence of trichomoniasis in cervical cancer patients was discovered to be the highest in the study by Ghosh et al. in Kolkata, India (72.6% women with CIN 1, 71.0% women with CIN 2 or CIN 3, and 87.7% women with invasive cancer) and the lowest in the study by Su et al.  in Taiwan (0.022%). The association between trichomoniasis and cervical cancer was found to be varied.
Manalagi Apple Vinegar (Malus sylvestris Mill) as Anti Diabetic to Alloxan Induced Wistar White Male Rat Valentina Verrel Purnomo; A. Sareh Arjono Tjandra; Risma Risma
Denta Journal Kedokteran Gigi Vol 2 No 1 (2019): Oceana Biomedicina Journal Volume 2 Issue (No) 1 January - June 2019
Publisher : Universitas Hang Tuah

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Apple vinegar is estimated to be able to cure diabetes. Vinegar is able to control the increase of glicemic index. Apple has antioxidant substance such as quercetin and chlorogenic acid. Manalagi apple could be found easily in Indonesia.This research aims to reveal the effect of Manalagi apple vinegar (Malus sylvestris Mill) towards blood glucose level of alloxan induced Wistar white male rats (Rattus norvegicus).This research is experimental laboratory using Experimental methods. The samples are 30 white rats divided into three groups for 31 days, 1) group which only given standard diet; 2) group that induced by 120mg/dL alloxan; 3) group that induced by 120mg/dL alloxan and Manalagi apple vinegar 0.27ml/100gram weight for 14 days. The measurement of blood serum glucose level is done on day twenty four using homogenous colorimetric enzymatic test method for all groups.Blood glucose average in group with only given standard diet as negative control group (182.33 mg/dL), group which induced by 120mg/dL alloxan as positive control group (205.2 mg/dL), group which induced by 120mg/dL alloxan and Manalagi apple vinegar as treatment group (212.25 mg/dL). The result of One-Way Anova significance is 0.229.The conclusion of this research is that Manalagi apple vinegar treatment doesn’t able to decrease the blood glucose level of white Wistar male rats significantly.
Efek Pemberian Infusa Daun Carica papaya Terhadap Perkembangan Vektor Larva Nyamuk Aedes aegypti VINA LIDYA SETJAPUTRA; STEVEN CHRISTIAN SUSIANTO; RISMA
HANG TUAH MEDICAL JOURNAL Vol 20 No 1 (2022): Hang Tuah Medical Journal
Publisher : Universitas Hang Tuah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30649/htmj.v20i1.183

Abstract

Background: Vector eradication is the most effective strategy to prevent Dengue Hemorrhagic Fever, particularly larvae elimination by larvicide. The papaya leaf (Carica papaya) contains several chemicals used as a larvicidal agent. This study aimed to determine the larvicidal activity of papaya leaf (Carica papaya) infusion against third instar Aedes aegypti larvae as dengue hemorrhagic fever prevention. Method: This was an experimental laboratory study with a post-test-only control group design. We used the third instar of Aedes aegypti mosquito larvae, divided into seven treatment groups, one positive control group, and one negative control group, containing 25 larvae each. The treatment groups were given papaya leaf infusion with concentration of 4%, 4,5%, 5%, 5,5%, 6%, 6,5%, 7%, respectively. The negative control group did not receive any treatment, and the positive control group received Temephos with 1 ppm dose. Larvae mortality was recorded after 24 hours, and we replicated the experiment 3 times. The mortality data were analyzed using a one-way ANOVA test for normally distributed and Kruskal Wallis for not normally distributed. Results: There were no significant differences between treatment groups and negative control group, except in concentration of 6,5% (p=0,034) and 7% (p=0,037) group, and significant differences between all treatment groups compared to the positive control group (p<0,05). Conclusion: Papaya leaf infusion as Aedes aegypti larvicide in concentrations of 6,5% and 7% showed a significant effect on larvae mortality after 24-hour. However, compared to Temephos, it was a less larvicidal effect.
Co-Authors A. Sareh Arjono Tjandra I Made Prasetya Kurniawan Jonathan Payangka Luh Putu Diah Ayuning Prawesty Diah Utami Prawesty Diah Utami STEVEN CHRISTIAN SUSIANTO Valentina Verrel Purnomo VINA LIDYA SETJAPUTRA Wibowo, Prajogo