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Analisis Kadar Kalsium Saliva dan Hubungannya dengan Pembentukan Karang Gigi Kuswandani, Faisal
Indonesian Journal of Pharmaceutical Science and Technology Vol 3, No 1 (2016)
Publisher : Indonesian Journal of Pharmaceutical Science and Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (236.597 KB) | DOI: 10.15416/ijpst.v3i1.7914

Abstract

Kalsium dan fosfat di dalam saliva penting dalam proses remineralisasi email dan berperan juga dalam pembentukan karang gigi. Penelitian ini bertujuan untuk mengetahui hubungan antara kadar kalsium saliva dengan pembentukan karang gigi. Sampel dilarutkan dalam larutan lanthanum (III) klorida konsentrasi tinggi yang berfungsi untuk  mengikat ion-ion pengganggu. Kadar kalsium di dalam saliva dianalisis dengan Spektroskopi Serapan Atom Nyala. Hasil penelitian menunjukkan bahwa kadar kalsium saliva adalah 56,84 ppm sampai 121,91 ppm. Sampel dari kelompok studi memiliki kadar kalsium rata-rata 95,34 dan sampel dari kelompok pembanding memiliki kadar kalsium rata-rata 78,13 ppm. Dari hasil penelitian dapat disimpulkan bahwa sampel dari kelompok studi memiliki kadar kalsium lebih besar dari pada sampel dari kelompok pembanding, yang berarti bahwa semakin besar kadar kalsium dalam saliva akan semakin mudah seseorang terkena karang gigi. Kata kunci: Kalsium, karang gigi, saliva, spektroskopi serapan atom nyala
Antimicrobial Efficacy of Myrmecodia pendens Extract and Fraction Combination against Enterococcus faecalis ATCC 29212 Kuswandani, Faisal; Satari, Mieke H; Maskoen, Ani M
Journal of Dentistry Indonesia
Publisher : UI Scholars Hub

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Enterococcus faecalis can withstand harsh environmental conditions in the root canal and cause a secondary infection. Myrmecodia pendens is an herbal medicine rich in polyphenol compounds that have antibacterial, antioxidant, and anticancer properties. Objectives: To analyze the effects of M. pendens fraction combination on the sensitivity of E. faecalis. Methods: The minimum inhibitory concentration (MIC) was determined using a serial microdilution method, and the minimum bactericidal concentration (MBC) was determined by adding the test sample to sterile Mueler Hinton agar medium. Results: The MIC of combination 1 (hexane-ethyl acetate, HE) was 0.049 mg/mL, whereas those of combinations 2 (hexane-water, HA) and 3 (ethyl acetate-water, EA) were 0.098 and 0.390 mg/ mL, respectively. The MIC of NaOCl was 0.390 mg/mL, and that of methanol extract was 0.390 mg/mL. The MBC of combination 1 (HE) was 12.50 mg/mL, whereas that of combinations 2 (HA) and 3 (EA) was 50 mg/mL. The MBC of NaOCl was 25 mg/mL and that of methanol extract was 50 mg/mL against E. faecalis. This study showed that fraction combinations increase the antibacterial effect of M. pendens against E. faecalis ATCC 29212. Conclusion: The HE fraction combination showed the best effect against E. faecalis and can be developed as an alternative endodontic irrigant
Analisis Kadar Kalsium Saliva dan Hubungannya dengan Pembentukan Karang Gigi Faisal Kuswandani
Indonesian Journal of Pharmaceutical Science and Technology Vol 3, No 1 (2016)
Publisher : Indonesian Journal of Pharmaceutical Science and Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (236.597 KB) | DOI: 10.24198/ijpst.v3i1.7914

Abstract

Kalsium dan fosfat di dalam saliva penting dalam proses remineralisasi email dan berperan juga dalam pembentukan karang gigi. Penelitian ini bertujuan untuk mengetahui hubungan antara kadar kalsium saliva dengan pembentukan karang gigi. Sampel dilarutkan dalam larutan lanthanum (III) klorida konsentrasi tinggi yang berfungsi untuk  mengikat ion-ion pengganggu. Kadar kalsium di dalam saliva dianalisis dengan Spektroskopi Serapan Atom Nyala. Hasil penelitian menunjukkan bahwa kadar kalsium saliva adalah 56,84 ppm sampai 121,91 ppm. Sampel dari kelompok studi memiliki kadar kalsium rata-rata 95,34 dan sampel dari kelompok pembanding memiliki kadar kalsium rata-rata 78,13 ppm. Dari hasil penelitian dapat disimpulkan bahwa sampel dari kelompok studi memiliki kadar kalsium lebih besar dari pada sampel dari kelompok pembanding, yang berarti bahwa semakin besar kadar kalsium dalam saliva akan semakin mudah seseorang terkena karang gigi. Kata kunci: Kalsium, karang gigi, saliva, spektroskopi serapan atom nyala
Pharmacy staffing and workload in RSGM Unpad using Workload Indicators of Staffing Needs (WISN) method Faisal Kuswandani; Dwintha Lestari; Felisha F. Balafif
Indonesian Journal of Clinical Pharmacy Vol 10, No 3 (2021)
Publisher : Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15416/ijcp.2021.10.3.198

Abstract

Introduction : One of the challenges in the health facility is the balance between the number of staff and workloads to achieve quality, effectiveness and efficiency. Developing countries that have limited resources and budgets finds out difficult to achieve it. This study aims to analyze the workload at Pharmacy RSGM Unpad using the Workload Indicators of Staffing Needs (WISN) from the World Health Organization (WHO). Methodology: The study employed descriptive cross-sectional design and the Workload Indicator of Staffing Needs (WISN) methodology. Conducted in May 2020. We utilized observations, discussion and interviews to obtain information from staff; document review from hospital's records in 2019. Results :  Available work time in a year were 97440 minutes. As a result, the staffing needed  the Inpatient-outpatient department in Pharmacy RSGM Unpad were 4 people and in the logistic-purchasing department in Pharmacy RSGM Unpad were 2 people. The WISN ratio was obtained at 1.17 (> 1) which means the workload and number of staff at Pharmacy RSGM Unpad were not appropriate (overstaff). Conclusion : Based on the analysis using the WISN method, the number of staff in the Pharmacy RSGM Unpad is overstaff the existing workload. The Pharmacy RSGM Unpad can redistribute staff and develop pharmaceutical satellites to increase effectiveness and efficiency.
Plants for oral biofilms eradication: literature review Amatul Firdaustia PRATIWI; Hening Tjaturina PRAMESTI; Faisal KUSWANDANI
Journal of Syiah Kuala Dentistry Society Vol 6, No 2 (2021): December 2021
Publisher : Dentistry Faculty

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/jds.v6i2.24193

Abstract

ABSTRACT Oral Biofilm is a collection of microbial cell colonies related to periodontal diseases and caries. Biofilmbacteria were more resistant to antimicrobial agents than in the planktonic phase. The rapid progression of bacterialresistance to antimicrobial agents such as chlorhexidine has encouraged researchers to find alternative antimicrobialagents from natural plant products with low side effects. The purpose of this review was to summarize plants thatcontain bioactive compounds for biofilm eradication in terms of preventing caries and periodontal diseases. Themethod was used Systematic Review without Metha Analysis. Articles to be reviewed were searched from Pubmed,Cochrane, Science Direct, and Google Scholar databases using the PRISMA method and hand searching. The lastselected articles were analyzed using narrative analysis. There are 1,610 articles specified in the first stage and only18 articles left in the final extraction stage. Plants that contain bioactive compounds for oral biofilm eradicationinclude Piper betle (betel), Psidium sp., Mangifera sp., Mentha sp., Caesalpinia sappan (secang), Baccharis dracunculifolia,Laurus nobilis L. (dafnah), Croton nepetaefolius, Salvadora persica (miswak), Dryopteris crassirhizoma, Diospyros kakiThunb. (persimmon), Ginkgo biloba, Azadirachta indica (neem), Camellia sinensis, Lippia alba, Cymbopogon citratus(lemongrass), Citrus aurantifolius, Tamarindus indica (sour), Syzygium cumini (jamblang), Emblica officinalis (malacca),Acacia Arabica (prickly acacia), Terminalia chebula (myrobalan), Terminalia bellerica (bahera), Carica papaya, Ocimumbasilicum L. (basil), and Myrmercodia pendans. These plant bioactive compounds are belong to the group of alkaloids,terpenoids, and polyphenols which were tested in the form of single compounds or mixtures, especially againstStreptococcus mutans. In conclusion, 26 plant species have reported containing bioactive compounds tested in theform of single or mixed extracts to eradicate oral bacterial biofilm. KEYWORDS: Plants, eradication, natural products, oral biofilm