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Yovita Endah Lestari
Prodi Farmasi Universitas Malahayati
Environmental Science Medicine & Pharmacology

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ANTIOXIDANT ACTIVITY OF PETAI SELONG (Leucaena leucocephala) USING DPPH (1,1 diphenyl-2-picrylhydrazl) Saddam Husein; Erika Indah Safitri; Yovita Endah Lestari
Jurnal Farmasi Malahayati Vol 5, No 2 (2022)
Publisher : Jurnal Farmasi Malahayati (JFM)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/jfm.v5i2.8783

Abstract

Petai selong or petai china (leucaena leucocephala) is populary consumed in southeast asia, such as indonesia, thailand, the philippines and malaysia. This paper aims to anlayze the antioxidant activity of  petai selong (leucaena leucocephala) using DPPH(1,1 diphenyl-2-picrylhydrazl). The antioxidant activity is shown from the phytochemical analysis, degradation of DPPH, and kinetics degradation.  Phytochemical analysis was carried out by dripping petai selong extract with various reagent.DPPH was conducted by mixing the DPPH and extract petai selong with 8 ppm, 12 ppm, 16 ppm, 20 ppm, and 24 ppm. The degradation analysis was conduted using spectrofotometer UV-Vis, and the kinetics degradation were calculated using Langmuir Hinshelwood (L-H). The results show that the petai selong has an antioxidant acitivty. It is stated that the highest degradation occurs at 24 ppm where it degrades about 10 ppm of DPPH, or approximatly about96.14 percent, and the lowest degradation occurs at 8 ppm where it degrades about 2 ppm of DPPH, or approximatly about 0.98 percent. The Langmuir Hinselwood calculations show that the kinetics degradations of DPPH increase with petai selong concentration. It is stated that the higher of petai selong concentrations, the higher of antioxidant effect. 
PENGARUH PENGGUNAAN ANTIBIOTIK DI FASILITAS KESEHATAN (FASKES) TERHADAP KUALITAS PERAIRAN UMUM : STUDI POTENSI CEMARAN ANTIBIOTIK Saddam Husein; Vania Amanda Samor; Yovita Endah Lestari; Rachmi Nurkhalika
Jurnal Farmasi Malahayati Vol 6, No 2 (2023)
Publisher : Jurnal Farmasi Malahayati (JFM)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/jfm.v6i2.10400

Abstract

Penggunaan antibiotik di fasilitas kesehatan (FASKES) memiliki dampak signifikan terhadap kualitas perairan umum. Penelitian ini menyoroti bahwa pembuangan sisa-sisa antibiotik melalui limbah cair FASKES dapat menyebabkan kontaminasi antibiotik di lingkungan dan akhirnya mencemari perairan. Kontaminasi tersebut memiliki efek negatif pada ekosistem perairan dan kesehatan manusia. Pengelolaan limbah antibiotik yang tepat di FASKES sangat penting untuk mengurangi risiko kontaminasi antibiotik. Peraturan kebijakan dan panduan yang mengatur penggunaan antibiotik serta pengelolaan limbah di FASKES, bersama dengan peningkatan kesadaran dan edukasi di kalangan staf medis tentang penggunaan antibiotik yang bijaksana, sangat penting. Infrastruktur pengelolaan limbah yang memadai perlu dikembangkan untuk mengoptimalkan pengolahan limbah medis. Monitoring lingkungan secara rutin harus dilakukan untuk menilai tingkat kontaminasi antibiotik dan menerapkan langkah mitigasi yang diperlukan. Dengan langkah-langkah yang tepat, diharapkan penggunaan antibiotik di FASKES dapat memiliki dampak minimal terhadap kualitas perairan umum, menjaga kesehatan manusia, dan keberlanjutan lingkungan.
Co-Authors Erika Indah Safitri Rachmi Nurkhalika Saddam Husein Vania Amanda Samor