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All Journal e-CliniC Medika Tadulako Indonesian Journal of Obstetrics and Gynecology (Majalah Obstetri dan Ginekologi Indonesia)
Maya E. Mewengkang, Maya E.
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Health Professions Medicine & Pharmacology Public Health

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Lselectin Levels in Patients with Endometriosis Fanggidae, Melkiandri; Loho, Maria F.T.; Mewengkang, Maya E.
Indonesian Journal of Obstetrics and Gynecology Volume 6. No. 1. January 2018
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32771/inajog.v6i1.758

Abstract

Objective: To investigate the L-selectin profile in endometrioticpatients.Methods: This was a cross-sectional study. Subjects were patientsdiagnosed endometriosis based on clinical examination, transvaginalultrasound, MRI and CT scan at the Department of Obstetricsand Gynecology of Prof. Dr. R.D. Kandou Hospital Manado, SiloamHospital and Network Hospital starting from January 2017 to May2017. The blood samples in patients prior to surgery were taken ona vein and then separated to obtain serum. Further more, serumlevels of L-selectin were measured using enzyme-linked immunosorbentassay (ELISA). Data were analyzed with SPSS version 22.0to see significance level.Results: Of the 18 samples, based on age, endometriosis highest inthe group > 26 years ie 17 patients (94.44%), followed by the agegroup of 21-25 years in 1 patient (5:56%), and none of thepatients in the age group <20 years (0%). Based on parity, themost established on a parity group 0 for 11 patients (61.11%),followed by the 1-3 parity group of 7 patients (38.99%), and nopatients in the parity > 4 (0%). Based on the highest stage is thethird stage as many as 11 people (61.11%), followed by stage 4 of7 patients (38.99%), and none of the patients in stage 1 or stage 2(0%). From a statistical test used to stage endometriosis age, theT test, p value 0.286. From a statistical test according to the levelsof L-selectin on endometriosis stadium used, the T test, p value0.090. Results of correlation tests were used, namely statingPearson test p value of 0.921.Conclusion: L-selectin levels in women with endometriosisincreased according to clinical stage, but not significant in statisticaltests. There is no significant relationship between age withstages or levels of L-selectin in women with endometriosis.Keywords: adhesion, age, endometriosis, L-selectin, stage
Lselectin Levels in Patients with Endometriosis Fanggidae, Melkiandri; Loho, Maria F.T.; Mewengkang, Maya E.
Indonesian Journal of Obstetrics and Gynecology Volume 6. No. 1. January 2018
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32771/inajog.v6i1.758

Abstract

Objective: To investigate the L-selectin profile in endometrioticpatients.Methods: This was a cross-sectional study. Subjects were patientsdiagnosed endometriosis based on clinical examination, transvaginalultrasound, MRI and CT scan at the Department of Obstetricsand Gynecology of Prof. Dr. R.D. Kandou Hospital Manado, SiloamHospital and Network Hospital starting from January 2017 to May2017. The blood samples in patients prior to surgery were taken ona vein and then separated to obtain serum. Further more, serumlevels of L-selectin were measured using enzyme-linked immunosorbentassay (ELISA). Data were analyzed with SPSS version 22.0to see significance level.Results: Of the 18 samples, based on age, endometriosis highest inthe group > 26 years ie 17 patients (94.44%), followed by the agegroup of 21-25 years in 1 patient (5:56%), and none of thepatients in the age group <20 years (0%). Based on parity, themost established on a parity group 0 for 11 patients (61.11%),followed by the 1-3 parity group of 7 patients (38.99%), and nopatients in the parity > 4 (0%). Based on the highest stage is thethird stage as many as 11 people (61.11%), followed by stage 4 of7 patients (38.99%), and none of the patients in stage 1 or stage 2(0%). From a statistical test used to stage endometriosis age, theT test, p value 0.286. From a statistical test according to the levelsof L-selectin on endometriosis stadium used, the T test, p value0.090. Results of correlation tests were used, namely statingPearson test p value of 0.921.Conclusion: L-selectin levels in women with endometriosisincreased according to clinical stage, but not significant in statisticaltests. There is no significant relationship between age withstages or levels of L-selectin in women with endometriosis.Keywords: adhesion, age, endometriosis, L-selectin, stage
DIFFERENCE IN SERUM LIPID PROFILE VALUE IN PREGNANCY AND POSTPARTUM ON SEVERE PREECLAMPSIA White, I Putu F.I; Wantania, John J.E; Mewengkang, Maya E.
Medika Tadulako: Jurnal Ilmiah Kedokteran Fakultas Kedokteran dan Ilmu Kesehatan Vol 6, No 1 (2019)
Publisher : Medika Tadulako: Jurnal Ilmiah Kedokteran Fakultas Kedokteran dan Ilmu Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

ABSTRACT Objective: Uncovering the connection of serum lipid profile (total cholesterol, triglyceride, HDL, LDL, VLDL) with preeclampsia in pregnancy and postpartum, and its outcome. Method: This is a cross-sectional comparative analytic study Result: From 28 preeclampsia subject were found, mean value of systole 165.36 mmHg and 105.71 diastole. Serum lipid profile in pregnancy and postpartum has a significant differences and correlated with preeclampsia, total cholesterol 234.5 mg/dl and 192.71 mg/dl, p=0.000; medium positive in pregnancy with systole r=0.461; p=0.013, weak positive with diastole r=0.380; p=0.046; postpartum with systole medium positive r=0.615; p=0.001, and weak positive with diastole r=0.317; p=0.100. LDL 140.5 mg/dl and 102.5 mg/dl, p=0.000; pregnancy and systole r=0.446; p=0,017; and postpartum were medium positive r=0.546; p=0.003. HDL 51.5 mg/dl and 43.5 mg/dl, p=0.003; not correlated with BP. Triglyceride 268.89 mg/dl and 208.96 mg/dl, p=0.000; pregnancy r=0.516; p=0.005; postpartum r= 0.515; p=0.005 has medium correlation with systole. VLDL 53.78 mg/dl and 41.79, p=0.000; pregnancy r=0.461; p=0.013 systole medium positive; r=0.380; p=0.046 diastole weak positive; postpartum r=0,615; p=0,001 systole strong positive. Conclusion: All parameter of serum lipid profile in pregnancy and postpartum has significant differences and related with severe preeclampsia. Total cholesterol, LDL, triglyceride, and VLDL correlated with BP in severe preeclampsia. Key word: endothelial dysfunction, lipid profile, preeclampsia
PERBANDINGAN PERSALINAN SEKSIO SESAREA DAN PERVAGINAM PADA WANITA HAMIL DENGAN OBESITAS Ekwendi, Adelia S.; Mewengkang, Maya E.; Wagey, Frank M. M.
e-CliniC Vol 4, No 1 (2016): Jurnal e-CliniC (eCl)
Publisher : Universitas Sam Ratulangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35790/ecl.v4i1.10951

Abstract

Abstract: Obesity is a problem throughout the world and is commonly found among women in the region of Southeast Asia. Obesity in pregnant women increases the risk of complications associated with an increasing incidence of caesarean section and a decreasing incidence of vaginal delivery. This study aimed to determine the comparison of caesarean section and vaginal delivery in pregnant women with obesity. This was a descriptive study with a cross-sectional approach. This study used data of the patients’ medical record. Samples were all pregnant women with obesity (BMI ≥30 kg/m2) at the end of pregnancy who underwent caesarean sections and vaginal deliveries in Prof. Dr. R. D. Kandou Hospital Manado from January 2014 until October 2015. The data were processed by using the Microsoft Excel. The results showed that the number of pregnant women with obesity was 926 and of pregnant women who underwent caesarean section was 50.22%. Pregnant women with obesity in the age group over 30 years, nutritional status obese II and III, and body weight over 85 kg were more frequent in undergoing the cesarean section. Conclusion: The higher BMI, body weight, and age of a pregnant woman, the higher risk of undergoing cesarean section compared to vaginal delivery. Keywords: BMI, obesity, caesarean section, vaginal delivery   Abstrak: Obesitas merupakan masalah yang mendunia dan paling banyak dialami oleh wanita di wilayah Asia-Tenggara. Obesitas pada wanita hamil meningkatkan risiko terjadinya komplikasi yang berhubungan dengan peningkatan angka kejadian persalinan seksio sesarea dan penurunan kejadian persalinan pervaginam. Penelitian ini bertujuan untuk mengetahui perbandingan persalinan seksio sesarea dan pervaginam pada wanita hamil dengan obesitas. Penelitian ini menggunakan metode deskriptif dengan pendekatan potong lintang. Penelitian dilakukan dengan melihat catatan rekam medis pasien. Sampel penelitian ialah seluruh wanita hamil dengan obesitas (IMT ≥ 30 kg/m2) pada akhir kehamilan yang menjalani persalinan seksio sesarea dan pervaginam di RSUP Prof. Dr. R. D. Kandou Manado dari bulan Januari 2014 sampai Oktober 2015. Data yang diperoleh diolah dengan menggunakan Microsoft excel. Hasil penelitian menunjukkan bahwa jumlah wanita hamil dengan obesitas 926 orang dan yang menjalani seksio sesarea sebanyak 50,22%. Wanita hamil dengan obesitas pada kelompok umur di atas 30 tahun, status gizi obes II dan III, serta kelompok berat badan lebih dari 85 kg lebih banyak menjalani persalinan seksio sesarea. Simpulan: Semakin meningkat IMT, berat badan, dan usia seorang wanita hamil, maka semakin tinggi risiko menjalani persalinan seksio sesarea dibandingkan pervaginam. Kata kunci: IMT, obesitas, seksio sesarea, persalinan pervaginam
Gambaran Kehamilan dengan Luaran Makrosomia Periode Januari – Desember 2014 di RSUP Prof. Dr. R. D. Kandou Manado Osok, Stelaine; Wantania, John J. E.; Mewengkang, Maya E.
e-CliniC Vol 5, No 1 (2017): Jurnal e-CliniC (eCl)
Publisher : Universitas Sam Ratulangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35790/ecl.v5i1.14765

Abstract

Abstract: According to the American College of Obstetricians and Gynecologist and the World Health Organization, an infant who has a birth weight of more than 8 pounds (4.000 gram) is diagnosed as macrosomia. There are some risk factors that arise from fetal macrosomia such as diabetes, maternal obesity, and excessive weight gain during pregnancy. These risk are directly related to the birth weight of the infant and begin to increase substantially when birth weight exceeds 4.000 gram especially when it is more than 5.000 gram. This study was aimed to identify the description of pregnancy with macrosomia. This was a descriptive retrospective study. Data were obtained from patient records and survey in the Maternity Department of Prof. Dr. R. D. Kandou Manado. The results showed that the number of total pregnancies with macrosomia were 202 from 3,347 cases. The most common cases were multigravida with macrosomia (128 cases), gestational age 37-40 weeks (80 cases), maternal weight 61-80 kg (97 cases), and caesarean section as the type of labor (115 cases). Additionaly, most of the macrosomia cases were found in male infants, birth weight 4,000-4,250 grams (88 cases), and suffered from asphyxia.Keywords: the pregnancy, macrosomia Abstrak: Menurut American College of Obstetricians and Gynecologists and World Health Organization, bayi dengan berat lebih dari 8 ons, 13 ons (4.000 gram) disebut makrosomia. Beberapa faktor risiko yang terkait dengan janin makrosomia seperti diabetes serta ibu dengan obesitas dan kenaikan berat badan yang berlebihan selama kehamilan. Risiko ini secara langsung berhubungan dengan berat badan lahir bayi dan mulai meningkat secara substansial ketika berat badan lahir melebihi 4.500 gram dan terutama ketika melebihi 5.000 gram. Penelitian ini bertujuan untuk mengetahui gambaran kehamilan dengan luaran makrosomia. Jenis penelitian ialah deskriptif retrospektif menggunakan catatan rekam medik pasien dan pendataan di bagian ruang bersalin RSUP Prof. Dr. R. D. Kandou Manado. Hasil penelitian mendapatkan jumlah kehamilan dengan luaran makrosomia sebanyak 202 dari 3.347 kasus yang tercatat dan terbanyak pada usia ibu 35-40 tahun (42 kasus). Luaran makrosomia terbanyak pada multigravida (128 kasus), usia kehamilan 37-40 minggu (80 kasus), berat badan ibu 61-80 kg (97 kasus), dan jenis persalinan seksio sesarea (115 kasus). Luaran makrosomia terbanyak pada bayi laki-laki dengan berat badan 4.000-4.250 gram (88 kasus), dan pada bayi asfiksia. Simpulan: Jumlah makrosomia sebanyak 202 kasus, terbanyak pada usia ibu 35-40 tahun, multigravida, usia kehamilan 37-40 minggu, berat badan ibu 61-80 kg, persalinan seksio sesarea, terbanyak pada bayi laki-laki dengan berat badan 4.000-4.250 gram dan bayi asfiksia.Kata kunci: gambaran kehamilan, luaran makrosomia
GAMBARAN KARAKTERISTIK PENDERITA ENDOMETRIOSIS DI RSUP PROF. DR. R. D. KANDOU MANADO Wu, Indrani B.; Tendean, Hermie M.M.; Mewengkang, Maya E.
e-CliniC Vol 5, No 2 (2017): Jurnal e-CliniC (eCl)
Publisher : Universitas Sam Ratulangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35790/ecl.5.2.2017.18568

Abstract

Abstract: Endometriosis is a gynecology disease in which the endometrium grows outside of the uterine cavity. The endometrial tissue that keeps growing can cause irritation, pain, and infertility. The prevalence of endometriosis in women of reproductive age varies between 3-10% meanwhile the incidence endometriosis in infertile women is 9-50%. This study was aimed to obtain the characteristics of patients with endometriosis at Prof. Dr. R. D. Kandou Hospital, Manado from January 2016 to September 2017. This was a descriptive retrospective study, using medical record data of endometriosis patients at Prof. Dr. R. D. Kandou, Manado. The results showed 65 cases of endometriosis during that period but only 54 cases had complete data in the medical records. Endometriosis cases were more common among age of 36-45 years (50%), senior high school (61.1%), housewife (51.9%), married status (92.6%), nulipara (51.9%), menarche at age 12 years (35.2%), duration of menstruation for 5 days (29.6%), dysmenorrhoea (44.4%), endometriosis location in the ovarium (73.6%), endometriosis with stage 4 (51.9%), and treated with operation and medicine (51.9%). Conclusion: Most frequent characteristics patientswith endometriosis were 36-45 years old, senior high school, housewife, married, nulipara, menarche at age 12 years, duration of menstruation 5 days, dysmenorrhoea, location of endometriosis in the ovarium, stage 4 endometriosis, and treated with operation and medicine.Keywords: endometriosis Abstrak: Endometriosis merupakan penyakit ginekologis dimana endometrium tumbuh di luar rongga uterus. Jaringan endometrium yang terus tumbuh ini dapat menyebabkan iritasi, rasa nyeri, dan infertilitas. Prevalensi endometriosis pada wanita usia reproduksi bervariasi antara 3-10%. Pada kelompok wanita infertilitas angka kejadian sekitar 9-50%. Penelitian ini bertujuan untuk mengetahui gambaran karakteristik penderita endometriosis di RSUP Prof. Dr. R. D. Kandou Manado periode Januari 2016 ? September 2017. Jenis penelitian ialah deskriptif retrospektif, menggunakan data rekam medik penderita endometriosis di RSUP Prof. Dr. R. D. Kandou Manado. Hasil penelitian mendapatkan 65 kasus endometriosis selama periode tersebut tetapi pasien yang memiliki data rekam medik lengkap hanya 54 kasus. Distribusi endometriosis terbanyak pada kelompok usia 36-45 tahun (50%), pendidikan terakhir tingkat SLTA (61,1%), perkerjaan ibu rumah tangga (51,9%), status kawin (92,6%), nulipara (51,9%), usia menarche 12 tahun (35,2%), lama waktu menstruasi 5 hari (29,6%), keluhan utama nyeri haid (44,4%), lokasi pada ovarium (73,6%), endometriosis dengan stadium 4 (51,9%), dan penanganan secara operasi dan medikamentosa (51,9%). Simpulan: Karakteristik penderita endometriosis terbanyak pada kelompok usia 36-45 tahun, tingkat pendidikan SLTA, pekerjaan ibu rumah tangga, status kawin, nulipara, usia menarche 12 tahun, lama waktu menstruasi 5 hari, keluhan utama nyeri haid, lokasi endometriosis di ovarium, stadium 4, dan penanganan secara operasi dan medikamentosa.Kata kunci: endometriosis
Co-Authors Adelia S. Ekwendi, Adelia S. Fanggidae, Melkiandri Frank M. M. Wagey, Frank M. M. Hermie M.M. Tendean, Hermie M.M. John J. E. Wantania, John J. E. Maria F.T. Loho Osok, Stelaine Wantania, John J.E White, I Putu F.I Wu, Indrani B.