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All Journal e-GIGI MEDIA MEDIKA INDONESIANA Jurnal Kedokteran Diponegoro ODONTO Dental Journal Dental Journal (Majalah Kedokteran Gigi) Biosaintifika: Journal of Biology & Biology Education Odonto dental journal

Oedijani Oedijani, Oedijani

Department Of Dentistry, Faculty Of Medicine, Diponegoro University, Semarang, Indonesia, Indonesia

Author-ID : 581036

Agriculture, Biological Sciences & Forestry Dentistry Health Professions Medicine & Pharmacology

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ROLE OF COMBINATION CASEIN AND LACTOFERRIN BOVINE’S COLLOSTRUM AS A PULP CAPPING ON MACROPHAGE EXPRESSION IN MALE WISTAR RATS Endah Ariyati Eko Ningtyas; Oedijani Santoso; Udadi Sadhana; Siti Sunarintyas
Odonto : Dental Journal Vol 8, No 2 (2021): December 2021
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

ABSTRACTBackground: Inflammatory and/or non-inflammatory processes play a role in stimulating pulp repair and the formation of hard tissue, namely reparative dentin. Macrophages play a role in the pathogenesis and chronic inflammatory disorders. The combination casein lactoferrin of bovine colostrum as an immunomodulator has therapeutic potential. This study aims to determine the therapeutic effect and duration of application of the combination of casein lactoferrin of bovine colostrum, on the expression of macrophages as pulp capping.Method: This study was a true experimental laboratories post test only control group design, consisting of three groups of 60 male wistar rats with 4 observation times, namely day to day 7, 14, 21 and 28 each of 5 mice. The maxillary 1st molars were prepared until the roof of the pulp was exposed. Three groups, namely the combination of casein and lactoferrin bovine colostrum (CKL) and calcium hydroxide (K1) and the untreated group (K0). Each group was filled with glassionomer as a permanent restoration. The tissue was made histological preparations with hematoxylin-eosin staining and the number of macrophages were counted, then analyzed by two way ANOVA and post hoc LSD tests.Result: The results showed that the therapeutic effect and duration of application of the combination of casein and lactoferrin bovine colostrum on the expression of macrophages as pulp cappingConclusion: The combination of casein and lactoferrin of bovine colostrum as capping material can increase the number of macrophages in the healing process of dental pulp.

INFEKSI PERIODONTAL SEBAGAI FAKTORRISIKO KONDISI SISTEMIK Oedijani Santoso
Odonto : Dental Journal Vol 6, No 2 (2019): December 2019
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

According to Riskesdas 2018 the prevalence of dental and oral diseases in Indonesia is still high (57.6%) and the most cases are caries and periodontal disease. Periodontal tissue infection is a local oral infection that can be a focal oral infection, and has a risk of affecting systemic conditions. Microorganisms, toxins and inflammatory reactions in infected periodontal tissues can spread systemically to other parts of the body, thatcan cause infections in the area or worsen existing conditions. Systemic conditions that can be affected by periodontal tissue infections including coronary heart disease / arterosclerosis, stroke, diabetes mellitus, pregnancy, chronic pulmonary obstruction, acute respiratory infections. The purpose of this literature review is to refresh about oral focal infection, as well as more convincing that periodontal infection was a risk factor for systemic conditions, in terms of inflammatory reactions.Influencing inflammatory reactions are inflammatory mediators, including interleukin (IL-1α, IL-β, IL-6, IL-8), tumor necotic factors (TNFα) and prostaglandin E2 (PGE2). Biological mechanisms support the role of periodontal infection as a potential risk factor for a number of systemic conditions.Future multidisciplinary research should better illustrate the role of periodontal infections in systemic health, so that the influence between periodontal infections and systemic conditions such as premature LBW, diabetes, cardiovascular and cerebrovascular diseases, and respiratory diseases will be increasingly proven

CORRELATION OF SURFACE ROUGHNESS AND FRICTION RESISTANCE IN ORTHODONTICS Grahita Aditya; Oedijani Santoso; Lisyani Suromo; Reeza Maulana Nugraha
Odonto : Dental Journal Vol 9, No 1 (2022): July 2022
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Background: The orthodontic bracket transmit significant force from orthodontic wire to the teeth. Metal ions from the bracket may undergo biodegradation due to corrosion and create micro pit on the surface which increase friction resistance. Friction resistance between the archwire and the bracket may effect tooth movement and cause loss of anchorage. This study determine the correlation between surface roughness and friction resistance in orthodontic Roth brackets.Method: Seventeen brackets were prepared from previous study and were analyzed using SEM-EDX (Phenom Pro X) to measure surface roughness. Friction resistance were measured using universal testing machine. Data were analyzed using Spearman correlation.Result: Significant correlation were found between surface roughness and friction resistance on orthodontic brackets (p<0.05). The relationship is strongly correlated and directly proportional, with a positive coefficient value of 0.587. Conclusion: The conclusion of the research showed that there was a significant correlation between surface roughness and friction resistance of orthodontic brackets.

Co-Authors Aini Pramoda Wardani Donna Hermawati Endah Ariyati Eko Ningtyas Fatimah Muis, Fatimah Grahita Aditya Lisyani Suromo Muhammad Fiqih Sabilillah Nadia Hardini Nadia Hardini Nasya K. Mahandini Nila Kusumasari Nurin Aisyiyah Listyasari Omaran Ibrahim Mohammed Ali, Omaran Ibrahim Mohammed Reeza Maulana Nugraha Siti Sunarintyas Udadi Sadhana, Udadi Yayah Sopianah

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