Wa Ode Intan Nur Octina
Neurology Specialist Study Program, Medical Faculty, Brawijaya University, Saiful Anwar General Hospital, Malang, Indonesia

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Journal : Journal of Pain, Vertigo and Headache

PATHOPHYSIOLOGY IN CLUSTER HEADACHE: AN UPDATE Wa Ode Intan Nur Octina; Shahdevi Nandar Kurniawan
Journal of Pain, Headache and Vertigo Vol. 4 No. 1 (2023): March
Publisher : PERDOSSI (Perhimpunan Dokter Spesialis Saraf Indonesia Cabang Malang) - Indonesian Neurological Association Branch of Malang cooperated with Neurology Residency Program, Faculty of Medicine Brawijaya University, Malang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.jphv.2022.004.01.5

Abstract

Cluster headache (CH) is a rare and very painful primary headache syndrome, with an estimated population prevalence of 0.12%. This condition can be episodic (ECH), lasting from 7 days to a year. A consensus statement from the European Headache Federation defines refractory CCH as a CCH with at least three severe attacks per week, even though at least three consecutive trials of adequate preventive care have been tested and managed with both acute and preventive treatment. Inhaled oxygen and subcutaneous sumatriptan are the two most effective acute treatment options for people with CH. Several preventive medications are also available, and the most effective is verapamil. However, most of these agents are not supported by strong clinical evidence. In some patients, this option may be ineffective, particularly in those with chronic CH. Surgical procedures for chronic refractory forms of disorder should then be considered.