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All Journal Jurnal Farmasi Indonesia Jurnal Ayurveda Medistra
Anggelina Aprilia Pangalila
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Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health

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Kombinasi nanoemulsi Minyak Kemiri (Aleurites mollucana L.) dan Serbuk Daun seledri (Apium graveolens L.) pada Model Penyakit Alopesia Yonathan Tri Atmodjo Reubun; Anggelina Aprilia Pangalila
Jurnal Farmasi Indonesia Vol 20 No 1 (2023): Jurnal Farmasi Indonesia
Publisher : Fakultas Farmasi Universitas Setia Budi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31001/jfi.v20i1.1856

Abstract

Candlenut oil and celery leaves have been widely used by people in the world as a treatment for hair loss problems as well as strengthening hair roots and blackening hair. Hair loss disease or in the medical world called alopecia is a disease where the amount of hair loss is more than hair growth in general. The main cause pf alopecia generally occurs due to inflammation in the hair follicles. The purpose of this experimental animals used, namely male rabbits of the New Zealand White type. The study began by testing the phytochemical screening on each of the materials used. Furthermore, a combination of candlenut oil and celery powder was carried out to form a nanoemulsion preparation. After that, tests were carried out including pH, emulsion type, hair growth including hair weight and thickness of the shaving area. The results showed that the co,bination of candlenut oil and celery powder had a pH value of 6.30 with an emulsion type, namely oil in water (O/W) and had hair growth activity from test animals for 28 days with the average weight and thickness of hair 0.2458 and 1,15 cm. this result is better than average positive control product X with an average weight and thickness of 0.2076 and 1 cm. in addition, compared with the negative control, the results of weight and hair thickness were 0.0305 and 0.5 cm. based on these results, it was concluded that the combination of candlenut oil and celery powder had good hair growth activity in experimental animals so that it could be used as treatment therapy for alopecia patients.
Review: Pemanfaatan Obat Herbal pada Penyakit Alzheimer dari Tiga Tanaman di Indonesia Anggelina Aprilia Pangalila
Jurnal Ayurveda Medistra Vol 4 No 2 (2023): Jurnal Ayurveda Medistra
Publisher : STIKes Medistra Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51690/medistra-jurnal123.v4i2.70

Abstract

Alzheimer's disease is a disease in which brain damage is characterized by a decrease in attention, memory, and personality. Personality changes often occur when sufferers become less spontaneous, more apathetic, and withdrawn from their environment. The use of chemical drugs derived from the synthesis of natural drugs is approved for clinical use for Alzheimer's patients. Synthesis from natural materials is carried out because of the many chemical compounds contained in plants which have various biological and pharmacological effects. As for the use of natural medicines that are efficacious as antioxidants, anticoagulants, and anti-inflammatories, they are targets in the prevention of Alzheimer's disease where from these effects they can inhibit the acetylcholinesterase enzyme that plays a role in neurotransmitter damage. This journal review aims to maximize the use of natural medicines that have antioxidant effects from plants such as turmeric (Curcuma longa L.), gotu kola (Centella asiatica L.) and Kelor leaves (Moringa oleifera Lam.) so that these three plants are expected to have an effect. potential in the prevention of Alzheimer's disease which will be discussed extensively.
Co-Authors Yonathan Tri Atmodjo Reubun