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All Journal Acta Medical and Health Sciences (AMHS)
Dewi R Handayani
Unknown Affiliation
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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Differences in Mediterranean diet adherence on lipid profile and plasma atherogenic index in dyslipidemia patients Dewi R Handayani; Khomaini Hasan; Iis I Rakhmat; Endry Septiadi; Yudith Y Kusmala
ACTA Medical Health Sciences Vol. 1 No. 1 (2022): ACTA Medical Health Sciences
Publisher : ACTA Medical Health Sciences

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Abstract

Dyslipidemia is lipid metabolism disorder as indicated by increase in total cholesterol, triglycerides, Low Density Lipoprotein (LDL) and decrease in High Density Lipoprotein(HDL). Riset Kesehatan Dasar (RISKESDAS) Database in 2018 showed 12.6% Indonesian population aged 55-64 years had high cholesterol and very high LDL and triglycerides. The Mediterranean diet is non-pharmacotherapeutic treatments in the form of nutrition therapy for dyslipidemic patients. This study aimed to determine differences of adherence to the Mediterranean diet on lipid profile and Plasma Atherogenic Index (PAI) in dyslipidemic patients at a private clinic in Bandung. It used an observational analytic method with a prospective cohort of 30 dyslipidemia patients. Sampling was done by systematic random sampling technique. The subjects were divided into 3 categories based on adherence, namely low, medium and high, then lipid profile examination and PAI were assessed at the end of the month. Total cholesterol, LDL, HDL data were analyzed using Anova and Post Hoc Tukeywhile triglycerides and PAI were analyzed using Kruskal Wallis and Mann Whitney. Adherence to the Mediterranean diet showed significant results on total cholesterol (p=0.007), LDL level (p=0.019), HDL level (p=0.006), triglycerides (p=0.005) and PAI (p=0.036). The result wasassociated due to the influence of food content rich in monounsaturated fatty acids (MUFA), polyunsaturated fatty acids (PUFA), phytosterols and polyphenols that affect the levels of lipid profiles and PAI.   DOI : 10.35990/amhs.v1n1.p1-9
Differences in mediterranean diet adherence on bmi, waist circumference, fat percentage, muscle mass in obesity Endry Septiadi; Dinar Mutiara; Henny Juliastuti; Iis I Rakhmat; Dewi R Handayani
ACTA Medical Health Sciences Vol. 1 No. 1 (2022): ACTA Medical Health Sciences
Publisher : ACTA Medical Health Sciences

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Abstract

Obesity is a multifactorial disease that occurs when there is an abnormal accumulation of body fat due to an imbalance between energy intake and energy expenditure. The prevalence of Riset Kesehatan Dasar in 2018 showed that 21.8% of the Indonesian population over 18 years is obese. One of the diets recommended by European Association for the Study of Obesity Community for obesity is the Mediterranean diet. This study aims to determine the difference of adherence level in the Mediterranean diet to nutritional status, and muscle mass in obese patients. The method used in this study is analytic observational with prospective cohort observations. Subjects in this study were 37 obese patients who were monitored for diet four times in one month with food frequency questionnaire and checked for BMI, waist circumference, body fat percentage, and muscle mass at the end of the month. BMI and body fat percentage were analyzed using the Anova test while waist circumference and muscle mass data were analyzed using the Kruskal Wallis test. The level of adherence to the Mediterranean diet has been shown to significantly affect BMI (p=0.008), waist circumference (p=0.042), body fat percentage (p=0.014), and muscle mass (p=0.009) in obese patients. This associated with the composition of Mediterranean diet which affects increase in thermogenesis, fat oxidation, anti-inflammatory, and increases satiety for a longer period. The results of this study support the hypothesis that there is the difference of adherence to the Mediterranean diet to nutritional status and muscle mass in obese patients.   DOI : 10.35990/amhs.v1n1.p28-37
Co-Authors Dinar Mutiara Endry Septiadi Henny Juliastuti Iis I Rakhmat KHOMAINI HASAN Yudith Y Kusmala