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All Journal JURNAL KESEHATAN YAMASI MAKASSAR
taufiq taufiq
AKADEMI FARMASI YAMASI
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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UJI MUTU FISIK SABUN MANDI CAIR EKSTRAK DAUN KERSEN (Muntingia calabura L) taufiq taufiq
Jurnal Kesehatan Yamasi Makassar Vol. 3 No. 1 (2019): Jurnal Kesehatan
Publisher : Akademi Farmasi Yamasi Makassar

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Abstract

Telah dilakukan penelitian tentang Daun kersen dimana daun tersebut merupakan tumbuhan tropisyang termasuk ke dalam family Elaeocarpaceae yang mudah di jumpai. Ekstrak daun kersen terbuktimemiliki adanya senyawa flavonoid, tannin,dan saponin. Daun kersen dalam pengobatan luar berkhasiatsebagai antibakteri. Di mana senyawa flavonoid yang terdapat dalam daun kersen mampu menghambataktivitas dari bakteri. Penelitian ini bertujuan untuk membuat formula sabun mandi cair yang bermutu danstabil dalam penyimpanan serta mengetahui evaluasi sifat fisika dan kimia sediaan sesuai standar.Ekstrak daun kersen diperoleh dengan cara maserasi selama 3 x 24 jam menggunakan pelarut etanol 70%,lalu di saring dan di rotari evaporator sampai diperoleh ekstrak kental. Evaluasi sediaan meliputipemeriksaan uji organoleptis, uji pH, dan uji Tinggi busa . Hasil menunjukkan bahwa sabun mandicair yang diformulasi dari ekstrak etanol daun kersen 15% berwarna hijau kecoklatan, berbentukcair, berbau khas dan pH sediaan berkisar 6 – 8, serta memiliki tinggi busa 74 mm – 80 mm. Formulatersebut mendekati kriteria sabun mandi cair menurut SNIKata kunci : Daun kersen, maserasi, sabun mandi cair,uji mutu fisik
UJI EFEK ANALGESIK EKSTRAK ETANOL UMBI BAWANG DAYAK (Eleutherine americana L. Merr) PADA MENCIT JANTAN (Mus musculus) admin; Taufiq Taufiq
Jurnal Kesehatan Yamasi Makassar Vol. 6 No. 1 (2022): Jurnal Kesehatan
Publisher : Akademi Farmasi Yamasi Makassar

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Abstract

This study was conducted to determine the analgesic effect of the ethanolic extract of Dayak onion bulbs (Eleutherinr americana L. Merr) on male mice (Mus musculus). 15 adult male mice were used which were divided into 5 groups and each group consisted of 3 animals with stretching observation time from 5 minutes to 60 minutes. Group I was given 1% Na CMC as a negative control, group II, III, and IV were given ethanol extract of Dayak Onion Bulbs with extract doses of 1.17 mg/0.5 ml, 2.34 mg/0.5 ml, and 4.68 mg/0.5 ml with a volume of 1 ml /30-gram BW orally with a volume of 1 ml/30 g body weight of mice. The results of the study on the administration of Dayak onion bulb extract (Eleutherine americana L. Merr) with extract doses of 1.17 mg/0.5 ml, 2.34 mg/0.5 ml, and 4.68 mg/0.5 ml, respectively. -the average percentage of stretching (19.48 %), (36.02 %), (62.11% %), while the administration of mefenamic acid suspension was 1.3 g/0.5 ml, the percentage of stretching was (76 ,48 %). Statistical test using SPSS 25 with the one way ANOVA method on the LSD follow-up test to see whether there is a difference in the analgesic effect of the extract shows a significant value of 0.000 (p < 0.005), which means that there is a significant difference between treatments (significant), at a confidence level of 5 % (α = 0.05).
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