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All Journal Formosa Journal of Sustainable Research (FJSR)
Rury Trisa Utami
Institut Kesehatan Mitra Bunda
Computer Science & IT Decision Sciences, Operations Research & Management Education Industrial & Manufacturing Engineering Social Sciences

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In Vitro Anti-Inflammatory Test of Genjer Leaf Extract (Limnocharis Flava) Yufri Aldi; Nurliyasman; Herwinda Julia Putri; Rury Trisa Utami
Formosa Journal of Sustainable Research Vol. 2 No. 5 (2023): May, 2023
Publisher : PT FORMOSA CENDEKIA GLOBAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55927/fjsr.v2i5.4196

Abstract

Tanaman genjer (Limnocharis flava L.) telah banyak dimanfaatkan untuk menjaga kesehatan pencernaan, mempercepat penyembuhan luka, menjaga kesehatan kulit, membantu menurunkan kolesterol. Senyawa fitokimia flavonoid yang terkandung dalam daun genjer diduga berkhasiat sebagai anti-inflamasi. Penelitian ini bertujuan untuk mengetahui aktivitas anti-inflamasi ekstrak daun genjer dengan menggunakan metode stabilitas membran eritrosit. Variasi konsentrasi larutan uji yang dibuat adalah 6 variasi konsentrasi yaitu 10, 50, 100, 250, 500 dan 1000 ppm. Aktivitas anti-inflamasi ekstrak kemudian dibandingkan dengan standar ibuprofen. Dari hasil uji aktivitas anti-inflamasi menggunakan metode stabilitas membran eritrosit berdasarkan perhitungan persen stabilitas menunjukkan bahwa ekstrak daun genjer pada konsentrasi 1000 ppm memiliki aktivitas tertinggi yaitu sebesar 76,70%. Dengan demikian konsentrasi ini dapat dikatakan sebagai konsentrasi tertinggi / efektif dalam memberikan perlindungan membran sel darah merah yang diinduksi larutan hipotonik. Berdasarkan hasil uji ANOVA satu arah diketahui bahwa pemberian ekstrak daun genjer berpengaruh nyata terhadap stabilitas membran eritrosit (p <0,05). Dari penelitian yang telah dilakukan dapat disimpulkan bahwa ekstrak daun genjer memiliki efek anti-inflamasi dengan menggunakan metode uji stabilitas membran eritrosit.
Antiseptic Activity of Combination Lotion of Herbal Extracts of Gotu Kola (Centella Asiatica (L). Urban) and Aloe Vera Against Psedomonas Aeruginosa Bacteria Delladari Mayefis; Rury Trisa Utami; Mulyani Ardian Ningsih
Formosa Journal of Sustainable Research Vol. 2 No. 9 (2023): September, 2023
Publisher : PT FORMOSA CENDEKIA GLOBAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55927/fjsr.v2i9.4765

Abstract

To test the antibacterial activity of antiseptic gel, a combination of gotu kola herb extract and aloe vera extract against pseudomonas aeruginosa bacteria. Experimentally using the well diffusion method with a combined concentration of gotu kola and aloe vera herbal extracts of 5%:5% (F IV), 7.5%:2.5% (F V), 7.5%:2.5% (F VI), with positive control using antic antiseptic. The antibacterial activity with the antiseptic combination of gotu kola and aloe vera herbal extracts against pseudomonas aeruginosa bacteria has a medium category inhibitory power of 18.06 mm. The data obtained was tested for normality using the Shapiro Wilk test followed by the One Way Anova test. Based on statistical tests using ANOVA, it shows that there is a significant difference between the average percentage values between groups (sig ≤ 0.05). The single lotion activity and antibacterial combination of gotu kola and aloe vera herbal extracts can inhibit the growth of pseudomonas aeruginosa bacteria
Isolation of Endophytic Fungi in Rhizophora Apiculata Mangroves in Teluk Buo Mangrove Area, Bungus Teluk Kabung District, West Sumatra Rury Trisa Utami; Delladari Mayefis; Hesti Marliza
Formosa Journal of Sustainable Research Vol. 2 No. 9 (2023): September, 2023
Publisher : PT FORMOSA CENDEKIA GLOBAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55927/fjsr.v2i9.6005

Abstract

Endophytic fungi are microbes that live in plant tissues that are able to produce secondary metabolite compounds and have the potential to be antibacterial, antifungal and anticancer. Purpose: To isolate endophytic fungi on mangrove plants Rhizophora apiculata that can be used as antibiotics. Method: This study was conducted experimentally in the microbiology laboratory by isolating endophytic fungi in mangrove roots, after isolation followed by microscopic observations to identify the type of fungus that grew. Results: Based on the results of observation and identification, the endophytic fungal genus Penicilium sp was successfully isolated from the mangrove roots of Rhizophora apiculata. Conclusion: Penicilium sp is an endophytic fungus obtained from the roots of the mangrove Rhizophora apiculata
Co-Authors Delladari Mayefis Herwinda Julia Putri Hesti Marliza Mulyani Ardian Ningsih Nurliyasman Yufri Aldi