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All Journal Indonesian Journal of Pharmaceutical Science and Technology Kartika Jurnal Ilmiah Farmasi Jurnal Ilmiah Manuntung
Ririn Puspadewi, Ririn
Universitas Jenderal Achmad Yani
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Computer Science & IT Health Professions Immunology & microbiology Medicine & Pharmacology

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POTENSI DAUN RUMPUT BELANG SEBAGAI OBAT TRADISIONAL YANG BERKHASIAT ANTIMIKROBA Puspadewi, Ririn; Adirestuti, Putranti; Dewi, Mira Andam; A, Naomi Oktavia
Kartika Jurnal Ilmiah Farmasi Vol 4, No 2 (2016)
Publisher : Universitas Jenderal Achmad Yani, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (251.302 KB) | DOI: 10.26874/kjif.v4i2.66

Abstract

ABSTRAK Telah dilakukan penelitian tentang pengujian ekstrak etanol dari daun rumput belang terhadap pertumbuhan Staphylococcus aureus, Escherichia coli dan Shigella dysenteriae. Rumput belang (Zebrina pendula Schnizl.) merupakan tanaman hias yang budidayanya sangat mudah sehingga tanaman ini dapat ditemukan didataran rendah maupun dataran tinggi. Secara empiris memiliki rumput belang memiliki khasiat antara lain untuk mengatasi disentri dan bisul. Hasil pengujian ekstrak etanol 96 % terhadap Staphylococcus aureus memberikan hambatan terbesar pada konsentrasi 60% = 11,69±0,57 (mm),  Escherichia coli memberikan hambatan terbesar pada konsentrasi 80% = 12,83±0,68 (mm), Shigella dysenteriae memberikan hambatan terbesar pada konsentrasi 80% = 12,81±0,43 (mm). Hasil pemeriksaan golongan kandungan kimia pada ekstrak daun rumput belang terdapat flavonoid, polifenol, kuinon, monoterpenoid-seskuiterpenoid dan senyawa steroid-triterpenoid.  Kata kunci   :  daun rumput belang, Staphylococcus aureus, Escherichia coli dan Shigella dysenteriae ABSTRACT A research on the testing of the ethanol extract of the leaves of rumput belang on the growth of Staphylococcus aureus, Escherichia coli and Shigella dysenteriae. Striped grass (Zebrina pendula Schnizl.) Is an ornamental plant cultivation is very easy so that the plant can be found in lowland and highland. Empirically the leaves of rumput belang have properties among others, to overcome dysentery and ulcers. Results of testing the 96% ethanol extract against Staphylococcus aureus provide the biggest obstacle at a concentration of 60% = 11.69 ± 0.57 (mm), Escherichia coli provide the biggest obstacle at a concentration of 80% = 12.83 ± 0.68 (mm), Shigella dysenteriae provide the biggest obstacle at a concentration of 80% = 12.81 ± 0.43 (mm). Class examination results of chemical constituents in the leaves of rumput belang extracts are flavonoids, polyphenols, quinones, monoterpenoid-sesquiterpenoids and steroid-triterpenoid compounds. Keywords : the leaves of  rumput belang, Staphylococcus aureus, Escherichia coli and Shigella dysenteriae
KHASIAT UMBI BAWANG DAYAK (Eleutherine palmifolia (L.) Merr.) SEBAGAI HERBAL ANTIMIKROBA KULIT Puspadewi, Ririn; Adirestuti, Putranti; Menawati, Rizka
Kartika Jurnal Ilmiah Farmasi Vol 1, No 1 (2013)
Publisher : Universitas Jenderal Achmad Yani, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (171.446 KB) | DOI: 10.26874/kjif.v1i1.21

Abstract

Umbi bawang dayak (Eleutherine palmifolia (L.)Merr.) merupakan tanaman khas Kalimantan Tengah yang berasal dari Amerika tropis. Secara empiris umbi bawang dayak sudah digunakan masyarakat lokal untuk mengobati luka dan obat bisul. Berkaitan dengan hal tersebut, telah dilakukan penelitian untuk melihat aktivitas antimikrobanya terhadap mikroba kulit yaitu Staphylococcus aureus dan Trichophyton rubrum. Serbuk simplisia diekstraksi dengan menggunakan metode maserasi dalam pelarut etanol 96% redestilasi. Ekstrak diuji terhadap kedua mikroba di atas yang sering terlibat dalam pembentukan  luka. Pengujian ekstrak etanol terhadap kedua mikroba uji dilakukan denganmenggunakan metode difusi agar dengan teknik lubang perforasi. Hasil penelitian menunjukkan bahwa ekstrak etanol dapat menghambat pertumbuhan Staphylococcus aureus dengan konsentrasi hambat minimum (KHM) adalah 1% dengan diameter hambat (14,49±0,51) mm dan menghambat pertumbuhan Trichophyton rubrum dengan KHM 15% dengan diameter hambat (15,06±0,42) mm. Ekstrak etanol dengan konsentrasi 1% berpotensi sama dengan Tetrasiklin HCl pada konsentrasi 0,06% dengan diameter hambat (14,03±0,42)mm untuk Staphylococcus aureus. Hasil pengujian terhadap Trichophyton rubrum menunjukkan ekstrak etanol 15% berpotensi hampir sama dengan ketokonazol pada konsentrasi 0,2% dengan diameter hambat sebesar (14,00±0,61) mm. Penapisan fitokimia menunjukkan bahwa bahan uji mengandung senyawa flavonoid, polifenol, alkaloid, kuinon, tanin, steroid, monoterpenoid dan seskuiterpenoid.
EVALUASI PENGGUNAAN OBAT PENYAKIT DEGENERATIF DI POLIKLINIK SPESIALIS RAWAT JALAN RUMAH SAKIT UMUM PUSAT Dr. HASAN SADIKIN BANDUNG Kartidjo, Pudjiastuti; Puspadewi, Ririn; Sutarna, Titta; Purnamasari, Nira
Kartika Jurnal Ilmiah Farmasi Vol 2, No 1 (2014)
Publisher : Universitas Jenderal Achmad Yani, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (292.307 KB) | DOI: 10.26874/kjif.v2i1.10

Abstract

Telah dilakukan penelitian evaluasi penggunaan obat penyakit degeneratif di Poliklinik Spesialis Rawat Jalan Rumah Sakit Umum Pusat Dr. Hasan Sadikin Bandung, dengan tujuan untuk mengetahui kerasionalan penggunaan obat yang diresepkan dan digunakan untuk kasus penyakit degeneratif yaitu penyakit Diabetes Mellitus Tipe 2. Metode penelitian meliputi penelusuran pustaka, penetapan kriteria pasien dan kriteria obat, penyusunan kriteria penggunaan obat untuk penyakit Diabetes Mellitus Tipe 2, pengumpulan data, serta analisis data secara kuantitatif dan kualitatif. Data diambil secara retrospektif dari data Instalasi Farmasi  dan  data rekaman medik selama periode 14 Januari sampai dengan 31 Mei 2013. Analisa kuantitatif dilakukan untuk mengetahui pola penggunaan obat oleh pasien berdasarkan usia, jenis kelamin, pendidikan, pekerjaan, agama, diagnosis, golongan obat, dan bentuk sediaan. Analisa kualitatif dilakukan untuk mengetahui ketepatan indikasi, dosis, aturan pakai, lama pengobatan; kejadian duplikasi, efek samping obat dan interaksi obat. Hasil penelitian menunjukkan bahwa semua obat Anti Diabetes Mellitus yang digunakan tepat indikasi, terdapat 1 kasus yang kurang dosis, dan terdapat 4  aturan pakai yang kurang tepat. Lama pengobatan telah tepat, dan tidak ditemukan kejadian duplikasi pada pemberian obat. Terdapat 33 kejadian interaksi obat yang digolongkan berdasar intensitas interaksi yaitu terdiri dari  3 kejadian interaksi obat serius, 17 signifikan dan 13  minor. Berdasarkan hasil penelitian dapat disimpulkan bahwa perlu selalu dilakukan pengkajian resep lebih mendalam, terutama pada aturan pakai obat dan interaksi obat yang terjadi pada kasus Diabetes Mellitus Tipe 2 dengan komplikasi dan penyakit penyerta.
Optimization of Extraction from Sappan Wood and Its In uence on Food Bacterial Contaminants Adirestuti, Putranti; Puspadewi, Ririn; Mardatillah, Athina; Anggita, Dismayana; Helena, Meidy; Octavia, Alfa; Putri, Yosinta
Indonesian Journal of Pharmaceutical Science and Technology Suppl 1, No. 1 (2018)
Publisher : Indonesian Journal of Pharmaceutical Science and Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (355.904 KB) | DOI: 10.15416/ijpst.v1i1.16119

Abstract

Sappan wood has already known as an ingredient of jamu, especially in Central Java. If it dissolved in hot water, it will show a red color and has been used as health drink for blood current obstruction, diarrhea, blood cough, dysentry, malaria and tetanus. The red pigment of sappan wood contained avonoid and polyphenol. The two kind of extractions of sappan wood used in this experiment were obtained by boiling water extraction at 90oC in 15 minutes and maceration in ethanol 50% overnight. The aim of this research was to nd the potential of inhibiting sappan wood for presence of bacterial contaminants in food, such as Escherichia coli, Staphylococcus aureus, and Pseudomonas aeruginosa in several time storages. Microbial examination by observing visual characteristics of damage to the food model and the decrease number of food bacterial contaminants. The result showed that ethanol extract 10% of sappan wood inhibited a food bacterial contaminants in three days at cold temperatures storage (8-10OC), and percent decrease population of E. coli, S. aureus and P. aeruginosa were 99.74%, 96.28%, and 99.88%, respectively. Key words : Ethanol extract, food contaminant bacterias, inhibiting, sappan wood, water extract
DETEKSI Staphylococcus aureus dan Salmonella PADA JAJANAN SIRUP Puspadewi, Ririn; Adirestuti, Putranti; Abdulbasith, Afif
Jurnal Ilmiah Manuntung Vol 3 No 1 (2017): Jurnal Ilmiah Manuntung
Publisher : jurnal ilmiah manuntung akademi farmasi samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (543.431 KB) | DOI: 10.51352/jim.v3i1.87

Abstract

Microbial on food are caused by various factors such as nutrients, water, and temperature. If total amount of microbes increase it would damage food and if it ingested could affect grastrointestinal track. Snack, especially unregistered snack such as syrup in school is one of important problem to concerned. The purpose of this study is to detect the present of Staphylococcus aureus and Salmonella in syrup in four elementary schools in Cimahi. Detection of Staphylococcus aureus is done using BPA medium, while detection of Salmonella is using Indol test, methyl red test, Voges Proskauer test, Citrate test and Gram staining. The result shows that the syrup from the elementary school contains Staphylococcus aureus but not all of samples of syrup give positive result of Salmonella. Based on the requirements which in set in SNI that microbes in syrup should not be contain to Staphylococcus aureus is negative/ml and Salmonella is negative/25 ml, then syrup that sold in all four elementary schooldi not qualified.
ISOLASI MIKROBA TANAH YANG BERPOTENSI MENGHASILKAN ANTIMIKROBA Puspadewi, Ririn; Anugrah, Rina; Abdulbasith, Afif; Yunita, Intan
Jurnal Ilmiah Manuntung Vol 6 No 1 (2020): Jurnal Ilmiah Manuntung
Publisher : jurnal ilmiah manuntung akademi farmasi samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (321.788 KB)

Abstract

The soil is one of the habitats for microorganisms, in one gram soil there are millions of microorganism. Population microorganism per gram the rich soil of covering bacteria, actinomycetes, fungi, algae and protozoa. Garden having the potential to do exploration of isolation microorganisms. This is because land contains many organic compounds and minerals that is one ecosystem fertile to life and growth microorganisms. Whenever a microorganisms have proven produce substance antimicrobe so organisms of its potential as producer antibiotics. Material research the land, taken from the soil Faculty of Pharmacy Plant Garden of UNJANI, we did dilution and cultivated in a media potato dextrose broth. The isolate from medium broth was cultivating in a media potato dextrose agar, to obtained isolates single. Isolates obtained seen features macroscopic and microscopic. The results obtained isolates isolation two of the four isolates that can give inhibition to Escherichia coli but does not inhibition to Staphylococcus aureus.   Keywords: isolation, microbe, soil
Co-Authors Abdulbasith, Afif Abdulbasith, Afif Anggita, Dismayana Helena, Meidy Mardatillah, Athina Mira Andam Dewi, Mira Andam Naomi Oktavia A, Naomi Oktavia Nira Purnamasari, Nira Octavia, Alfa Pudjiastuti Kartidjo, Pudjiastuti Putranti Adirestuti, Putranti Putri, Yosinta Rina Anugrah, Rina Rizka Menawati, Rizka Titta Sutarna, Titta Tyas, Aditya Ayuning Yunita, Intan