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All Journal As-syifaa Jurnal Farmasi
A. Mumtihanah Mursyid, A. Mumtihanah
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Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology

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PERBANDINGAN MUTU BERDASARKAN PROFIL DISOLUSI TABLET GLIBENKLAMID PATEN DAN GENERIK YANG BEREDAR DI MAKASSAR Mursyid, A. Mumtihanah; Hasyim, Nursiah; Jauhari, Evy Fajrianti
Jurnal Ilmiah As-Syifaa Vol 8, No 1 (2016): AS-SYIFAA Jurnal Farmasi
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (121.561 KB) | DOI: 10.33096/jifa.v8i1.158

Abstract

A research of dissolution testing of patent and generic glibenclamide tablet have been done. The purpose of this research is to determine quality of patent and generic glibenclamide tablet that circulated in Makassar. Glibenclamide tablets patent and generic dissolution have been tested with paddle methode in 500 ml posfat buffer pH 7,4, medium was accomplished at 37 oC±0,5 the speed of 75 rpm. Aliquot retaken as much 5 ml is done at time intervas of 10, 20, 30, 45, and 60 mnutes and then, the concentrations is confiruxed by spektrofotometer UV-VIS at the 299 nm wavelength. Based on the dissolution experiment result, the acquired glibenclamide percentage that was dissolute from glibenclamide tablets generic A = 85,686 %, generic B = 81,336 % and paten = 126,665 % have fulfill the dissolution the condition according to British Pharmacphea 2008. That is the dissolute is not less than 75 % within 45 minutes. And the average of Dissolution value efficiency (ED) rate each glibenclamide tablet paten = 115,29 %, generic B = 72,409 % and generic A = 77,352 %.
FORMULASI DAN EVALUASI SALEP EKSTRAK DAUN GULMA SIAM (Chromolaena odorata L.) DENGAN VARIASI BASIS SALEP Hasrawati, A.; Famir, Yasir; Aztriana, Aztriana; Mursyid, A. Mumtihanah
Jurnal Ilmiah As-Syifaa Vol 11, No 1 (2019): AS-SYIFAA Jurnal Farmasi
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (149.872 KB) | DOI: 10.33096/jifa.v11i1.514

Abstract

Siam weed leaves are one of the plants that function as wound medicine. This study aims to produce a stable ointment dosage form. Siamese weed leaf extract is formulated in the form of ointment with a variety of bases consisting of a hydrocarbon base, absorption, water soluble and emulsion. Evaluation of physical stability includes organoleptic testing, homogeneity, pH, dispersion, viscosity and flow properties carried out before and after forced conditions. Forced conditions were carried out with stock storage for 10 cycles at 50 and 350. The results of the analysis showed that the viscosity of the preparations in all formulas changed after storage at 50 and 350 for 5 days. However, the statistical results show that all formulas did not experience significant changes between before and after the stress condition treatment.
ANALISIS PENGARUH TEMPAT PENYIMPANAN TERHADAP BESARNYA KANDUNGAN LOGAM Pb DAN Zn DALAM DAGING KORNET HABIS PAKAI KEMASAN KALENG Syakri, Syamsuri; Mursyid, A. Mumtihanah
Jurnal Ilmiah As-Syifaa Vol 5, No 1 (2013): AS-SYIFAA Jurnal Farmasi
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (113.147 KB) | DOI: 10.33096/jifa.v5i1.66

Abstract

This research was conducted with the aim to investigate the influence of storage on the size of the metal content of Pb and Zn to quality consumable products corned beef cans obtained from a grocery store or supermarket, and to determine the ratio between the metals Pb and Zn results, with SK. DG BPOM No.03725/ B / SK / VII / 89 maximum of metal contamination in food. In this study, the sampling method used is the method of random sampling in which sampling method from a single population and each population has an equal chance to be selected as sample. Analysis of heavy metal Pb in all samples showed uptake results ranged from 0.0000 to 0.0005, or may be heavy metal pollution Pb is very small. Total Pb (lead) was much less after storage in the refrigerator for 1 day of corned beef packaging consumables, it is possible the influence of the storage temperature. Analysis of Zn metal in the samples showed varying results, it is because the meat itself was contained zinc metal content. Total Zn (Zinc) also was less after storage in the refrigerator for 1 day of corned beef packaging consumables, it is possible the influence of storage temperature affect the metal content. Analysis of Pb (lead) and Zn (zinc) in a sample of corned beef canned consumables still below the threshold set by decree. SNI No. 7387:2009 above the maximum limit of metal contamination in food, so the packaging corned beef is still suitable for consumption and circulated in the market.Key words: Corned Meat Packaging Cans, Metal Pb, Zn Metal, Storage
Co-Authors Aztriana Aztriana, Aztriana Famir, Yasir Hasrawati, A. Jauhari, Evy Fajrianti Mustakim, Musfira Nurlina - Nursiah Hasyim Syamsuri Syakri