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Nur Ariska Nugrahani
Jurusan Kedokteran Gigi, Fakultas Kedokteran Gigi, Universitas Muhammadiyah Surakarta, Jawa Tengah, Indonesia
Health Professions Public Health Veterinary

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Effect Of Avocado Seed (Persea Americana Mill.) On The Growth Of Bacteria Prevotella Intermedia (In Vitro) Syifaul Amrodi Al Birro; Nur Ariska Nugrahani; Nina Runting; Noor Hafida Widyastuti
Jurnal EduHealth Vol. 14 No. 03 (2023): Jurnal EduHealt, Edition September 2023
Publisher : Sean Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54209/jurnaleduhealth.v14i3.2543

Abstract

Periodontitis is an inflammatory disease of the supporting tissues of the teeth caused by bacteria present in the dental plaque biofilm. Gingivitis and periodontitis are the most common periodontal diseases and are associated with bacteria Prevotella intermedia. Avocado seeds are one way to inhibit this bacteria. the aim of this study is to prove that avocado seed extract (Persea americana Mill.) has an antibacterial effect on bacterial growth Prevotella intermedia. This study was a pure laboratory experimental post-test only control group design. The research sample was divided into 10 groups, namely 8 groups of avocado seed extract with different concentrations, 1 positive control group (chlorhelxidinel glulconat 0,2%), and 1 negative control group (aquades). Avocado seed extract (Persea americana Mill.) has antibacterial power against bacteria Prevotella intermedia with Minimum Inhibitory Concentration (MIC) of 3.125% and Minimum Bactericidal Concentration (MBC) of 6.25%. Avocado seed extract has antibacterial power against the bacteria Prevotella intermedia with MIC 3.125% and MBC 6.25%.
Establishment Differences Odontoblast Like Cell On Reversible Pulpitis With MTA And Nano Hydroxyapatite Sell Duck Eggs (In Vivo Study) Rio Susilo Putra; Cahyani Cahyani; Nur Ariska Nugrahani; Aprilia Yuanita Anwaristi
Jurnal EduHealth Vol. 14 No. 03 (2023): Jurnal EduHealt, Edition September 2023
Publisher : Sean Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54209/jurnaleduhealth.v14i3.2570

Abstract

Reversible pulpitis is a pathological condition of the pulp which can return to normal when the etiology of the condition is removed. Reversible pulpitis can be treated with pulp capping treatments to stimulate formation odontoblast like cell. Alternative materials are mineral trioxide aggregate (MTA), Biodentine and Nano hydroxyapatite (nHA) from duck shells. Purpose: to find out whether there is a difference in the number of formations odontoblast like cell in reversible pulpitis with MTA and nano hydroxyapatite duck egg shell. in vivo laboratory experiment test only control design with the independent variables, namely MTA and Nano Hydroxyapatite duck eggs and the dependent variable, namely the difference in the number of formation Odontoblast like-cell. The sample used was the RA right molar tooth of a male Sprague Dawley rat. Results: The results obtained were (p value 0.001), there was a significant difference between the average number of formations odontoblast like cell in each treatment group and control group. Administration of Nano hydroxyapatite medicament from duck egg shells and MTA medicament in the treatment of pulp caps can increase the formation of odontoblast like cell in reversible pulpitis.
The Effect Of Coenzim Q10 On The Number Of Lymfocite Cells In Male Wistar Rats With Periodontitis Tara Yurian Nadhifa; Aprilia Yuanita Anwaristi; Nur Ariska Nugrahani; Dwi Kurniawati
Jurnal EduHealth Vol. 14 No. 03 (2023): Jurnal EduHealt, Edition September 2023
Publisher : Sean Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54209/jurnaleduhealth.v14i3.2621

Abstract

Periodontal disease is a dental and oral health problem in adult society. One of the periodontal diseases is periodontitis which is an inflammation of the periodontal tissue caused by accumulation of dental plaque which can lead to impaired masticatory function, tooth loss, alveolar bone damage, periodontal ligament damage, pocket formation, and gingival recession. Coenzyme Q10 acts as an antioxidant, the reduced form is ready to give electrons to deactivate ROS or block free radicals which can prevent oxidative stress thereby protecting lymphocyte cells and reducing the immune response which can lead to a reduction in inflammation in the periodontal tissues. The purpose of this study was to determine the effect of coenzyme Q10 on the number of lymphocyte cells in the gingiva of male wistar rats with periodontitis. The research method used is true experimental laboratory quantitative research with a research design that is a posttest only control group design with observation or observing the control group and the treatment group. The number of samples used was 24 rats. Observation of lymphocyte cells was carried out using a light microscope with a magnification of 200x and a magnification of 400x and then counted manually by the observer. The results showed that the significance value obtained in the One-Way ANOVA test was 0.000 (<0.05). Then, based on the results of the Post Hoc Least Significant Difference (LSD) test, it was found that the biggest difference in effect was in the K(-)5 group and the P5 group, where the difference was 59.00 with a significance value of 0.000 (<0.05). It can be concluded that there is an effect of coenzyme Q10 administration on the number of lymphocyte cells in the gingiva of male Wistar rats with periodontitis.
Co-Authors Aprilia Yuanita Anwaristi Cahyani Cahyani Dwi Kurniawati Nina Runting Noor Hafida Widyastuti Rio Susilo Putra Syifaul Amrodi Al Birro Tara Yurian Nadhifa