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All Journal Jurnal Pengabdian Magister Pendidikan IPA Journal of Law and Nation EDU-BIO : Jurnal Pendidikan Biologi Jurnal Serambi Biologi Jurnal Teknologi Laboratorium Medik Borneo
Nadira
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Education Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Neuroscience Public Health

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Journal : Jurnal Serambi Biologi

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Genetic Variation Analysis of the E6 HPV 16 Gene Using RFLP In Silico Annisa, Silvy; Rahmawati, Atika Ayu; Nadira; Khairani, Fidia Aura; Achyar, Afifatul
Jurnal Serambi Biologi Vol. 9 No. 1 (2024): Jurnal Serambi Biologi
Publisher : Department of Biology, Faculty of Mathematics and Natural Sciences, Universitas Negeri Padang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24036/srmb.v9i1.331

Abstract

Cervical cancer is cancer that attacks epithelial cells or the outer surface layer of the cervix. This cancer is most commonly caused by the high risk type of Human Papillomavirus. The RFLP method uses restriction enzymes to cut certain nucleotide sequences at specific positions that produce fragments of different lengths. The purpose of this study was to determine the polymorphism that occurs in the E6 gene of the HPV 16 virus. This research was conducted using RFLP in silico. Virtual descriptive methods are used to analyze data and collect information about the object of study. The restriction enzyme HpaII was used in this study. The results showed that there were two alleles (A1 and A2) out of a total of 15 sequences of the E6 HPV 16 gene in Popset 636528409 indicating that there was a genetic variation in the gene.
Co-Authors Abdul Wahid Zakaria Achyar, Afifatul Annisa, Silvy Hanipah I Ketut Seregig Irwadi, Didi Khairani, Fidia Aura Lukmanul Hakim Luwy Sartika M. Erik Panji Dwi Satya Maulidyasari Mega Utami Regina Putri Muhamad Darul Amimi Aziz Nurfaizah Rahmawati, Atika Ayu Ratu Sampurna Risnita Septiani, Fitria Sri Anika Cahayu Suwardji Yulia Hesti