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Journal : Jurnal Farmasi Galenika (Galenika Journal of Pharmacy)

Effect of Candesartan Usage on Uric Acid Levels : Pengaruh Penggunaan Candesartan Terhadap Kadar Asam Urat Rumi, Amelia; Budiyanto, Titi Dwi Cahyani
Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) (e-Journal) Vol. 9 No. 2 (2023): (October 2023)
Publisher : Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/j24428744.2023.v9.i2.15592

Abstract

Cardiovascular disease is caused by disorders of the heart and blood vessels. One of the risk factors for cardiovascular disease is hyperuricemia, which indicates a high uric acid level in the blood, namely ≥7.0 mg / dL in men and ≥6.0 mg/ dL in women. Candersatan is one of the main line therapies that are widely used in cardiovascular patients which in previous studies were known to affect uric acid levels. This study aims to determine the effect of the use of candersatan on uric acid levels in cardiovascular patients for 3 months. This study uses a cross-sectional study with a prospective approach that is by examining uric acid levels before and after three months using candersatan and analyzed using SPSS statistical test Paired test. Of the total samples that met in the inclusion and exclusion criteria were 19 patients, the results showed an increase in uric acid levels with a significance value of 0,012 (p = ≤0.05). So it can be concluded that the average uric acid level of patients before using candersatan was 5.44 mg / dL, and the average uric acid level after using candersatan for three months was 6.30 mg / dL which means that the used of 8 mg candersatan for three months had a significant effect on the increase in uric acid levels in cardiovascular patients.
Analysis of Therapy Satisfaction on the Quality-of-Life of Type 2 Diabetes Mellitus Patients at Anutapura Hospital Palu: Analisis Kepuasan Terapi Terhadap Kualitas Hidup Pasien Diabetes Melitus Tipe 2 di RSUD Anutapura Palu Zainal, Setiawati Fadhilah; Rumi, Amelia; Tamrin, M.; Rosita, Habiba; Hasymi, Abdurrahman; Alydrus, Rugayyah; Ambianti, Nurul
Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) (e-Journal) Vol. 10 No. 1 (2024): (March 2024)
Publisher : Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/j24428744.2024.v10.i1.16887

Abstract

Background: Type 2 Diabetes Mellitus (Type 2 DM) is a chronic disease characterized by increased blood glucose levels caused by impaired insulin function. In Palu City, Type 2 DM is the 2nd most common in Central Sulawesi with a total of 26,204 people. Objective: This study aims to determine the relationship between therapy satisfaction and the quality of life of Type 2 DM patients who perform outpatient treatment at Anutapura General Hospital, Palu. Methods: With a random sample approach, 100 respondents were used in this cross-sectional study that employed an observational method. Data collection used instruments in the form of a DMSAT (Diabetes Medication Satisfaction Tool) therapy satisfaction questionnaire and a DQOL (Diabetes Quality Of Life) quality of life questionnaire. Results: The results of the study were obtained on therapy satisfaction from Type 2 DM patients with the number of respondents in the very satisfied (1.0%), satisfied (90.0%), and quite satisfied (9.0%) categories while the results of the study of the quality of life of Type 2 DM patients 2 fall into the good category (38.0%), and the bad category (62.0%). The statistical analysis test used was the Spearman Rank Correlation test. The results of the Spearman Rank Correlation test value p = 0.037 or p <α (0.05), then H0 is rejected, which means that there is a relationship between satisfaction with therapy and quality of life in patients with Type 2 DM which is very weak. Conclusion: The conclusion in this study is that there is a very weak relationship between therapy satisfaction and quality of life of patients.