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Uji Toksisitas Subkronik Kombinasi Ekstrak Etanol Kunyit Dan Jahe Terhadap Fungsi Hepar Tikus Putih Angga Bayu Budianto; Irwandi Irwandi; A.M. Muslihin; Ratih Arum Astuti
JURNAL ETNOFARMASI Vol 1 (2022): JURNAL ETNOFARMASI
Publisher : Universitas Pendidikan Muhammadiyah Sorong

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (409.096 KB)

Abstract

Rimpang kunyit dan jahe merupakan tanaman tradisional yang berkhasiat sebagai antiinflamasi. Penelitian ini bertujuan untuk mengetahui toksisitas subkronik kombinasi ekstrak etanol rimpang kunyit dan jahe terhadap perubahan kadar SGPT, SGOT dan gambaran histopatologi organ hepar pada tikus putih. Metode ekstraksi yang digunakan adalah sokhletasi dengan pelarut etanol 70%. Penelitian ini menggunakan hewan uji tikus putih galur wistar jantan dan betina sebanyak 50 ekor yang dibagi menjadi 5 kelompok yaitu kontrol negatif (Tween 2%), dosis I (400 mg/kgBB), dosis II (700 mg/kgBB), dosis III (1000 mg/kgBB) selama 28 hari dan kelompok satelit (1000 mg/kgBB) ditambah 14 hari. Data hasil pemeriksaan SGPT dan SGOT dianalisis dengan menggunakan One Way Anova, hari terakhir tikus dikorbankan untuk dilihat gambaran histopatologi organ hepar. Hasil penelitian menunjukkan bahwa pemberian kombinasi ekstrak etanol rimpang kunyit dan jahe secara oral tidak memberikan efek toksik pada organ hepar tikus putih jantan dan betina yang dilihat dari hasil pemeriksaan kadar SGPT dan SGOT serta diamati dari parameter histopatologi.
Analisis Kadar Formalin pada Mie Basah yang Dijual oleh Pedagang Bakso di Kota Sorong Menggunakan Spektrofotometer UV-Visible Siti Fatma Zf; Ratih Arum Astuti; Lukman Hardia
Sci-tech Journal Vol. 3 No. 1 (2024): Sci-Tech Journal
Publisher : MES Bogor

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56709/stj.v3i1.232

Abstract

Noodles are a popular food among middle class people, both upper and lower classes because they taste delicious and are affordable. Wet noodles have a short shelf life due to their high water content, this is what encourages some sellers to use formaldehyde as a preservative. This examination means to decide if there is formalin content in examples of wet noodles sold by meatball brokers in Sorong City. Formalin investigation was completed subjectively and quantitatively. Subjective tests were done by adding chromatogenic corrosive to wet noodle tests and quantitative tests were completed to see the degree of formaldehyde contained in the examples utilizing an UV-noticeable spectrophotometer. The consequences of the subjective test showed that one example with code (S1) was recognized as sure for containing formaldehyde, which was demonstrated by the adjustment of the shade of the filtrate from brown to purple subsequent to being dribbled with chromatophic corrosive reagent and warmed in bubbling water. The total formalin content contained in sample S1 was 0.905%.