The distribution of Covid-19 cases in the Batang regency increased to 9,924 confirmed cases from its first identification on April 4, 2020, until December 2021. The potential distribution of Covid-19 instances in 2020 and 2021 is in low land near the regency's main road access. This study aims to analyze the potential distribution of Covid-19 in an area based on environmental characteristics by a spatial approach based on location quotient (LQ) in the Batang regency for 2 consecutive years. The type of research is descriptive with a spatial explanatory design with a sample were 248 villages in the Batang regency. The results showed that 248 villages were confirmed to have Covid-19 with a very high potential distribution (LQ> 1.2) were 53 (21.4%) villages, the high potential distribution (1.05 2.58 in both 2020 and 2021 with the distribution pattern forming a cluster.